Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Suzana Guimarães, Leitão"'
Autor:
Rodrigo Michelini de Oliveira Thomasi, Thaiz Rodrigues Teixeira, Gabriela Francine Martins Lopes, Simony Carvalho Mendonça, Brendo Araujo Gomes, Suzana Guimarães Leitão, Tiago Alves de Oliveira, Sara Thamires Dias da Fonseca, Alex Gutterres Taranto, Jaqueline Maria Siqueira Ferreira, Luciana Alves Rodrigues dos Santos Lima, Ana Hortência Fonsêca Castro
Publikováno v:
Microbiology Research, Vol 15, Iss 2, Pp 582-597 (2024)
Zika virus (ZIKV) is involved in the etiology of serious nervous system pathologies. Currently, there are no specific and effective vaccines or antiviral drugs to prevent the diseases caused by ZIKV. This study aimed to assess the activity of flavono
Externí odkaz:
https://doaj.org/article/fb0ca4d4250843f4a76af185ba8b5e85
Autor:
André Mesquita Marques, Lavinia de Carvalho Brito, Simony Carvalho Mendonça, Brendo Araujo Gomes, Flávia da Cunha Camillo, Gustavo Werneck de Souza e Silva, André Luiz Franco Sampaio, Suzana Guimarães Leitão, Maria Raquel Figueiredo
Publikováno v:
Molecules, Vol 29, Iss 18, p 4357 (2024)
Background: Athenaea fasciculata, a Brazilian native species from the Solanaceae family, is recognized as a promising source of bioactive withanolides, particularly Aurelianolide A and B, which exhibit significant antitumoral activities. Despite its
Externí odkaz:
https://doaj.org/article/e2e0c7a0ab02465f9526ffc4a0f33837
Autor:
Simony Carvalho Mendonça, Brendo Araujo Gomes, Mariana Freire Campos, Thamirys Silva da Fonseca, Maria Eduarda Alves Esteves, Bruce Veiga Andriolo, Caio Felipe de Araujo Ribas Cheohen, Larissa Esteves Carvalho Constant, Stephany da Silva Costa, Pedro Telles Calil, Amanda Resende Tucci, Thamara Kelcya Fonseca de Oliveira, Alice dos Santos Rosa, Vivian Neuza dos Santos Ferreira, Julia Nilo Henrique Lima, Milene Dias Miranda, Luciana Jesus da Costa, Manuela Leal da Silva, Marcus Tullius Scotti, Diego Allonso, Gilda Guimarães Leitão, Suzana Guimarães Leitão
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 436 (2024)
The LABEXTRACT plant extract bank, featuring diverse members of the Myrtaceae family from Brazilian hot spot regions, provides a promising avenue for bioprospection. Given the pivotal roles of the Spike protein and 3CLpro and PLpro proteases in SARS-
Externí odkaz:
https://doaj.org/article/0277a49c1be843239ec3df752d2d7ce8
Autor:
Caio Felipe de Araujo Ribas Cheohen, Maria Eduarda Alves Esteves, Thamirys Silva da Fonseca, Carla Monteiro Leal, Fernanda de Lemos Fernandes Assis, Mariana Freire Campos, Raianne Soares Rebelo, Diego Allonso, Gilda Guimarães Leitão, Manuela Leal da Silva, Suzana Guimarães Leitão
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1461-1472 (2023)
Since the advent of Covid-19, several natural products have been investigated regarding their in silico interactions with SARS-CoV-2 proteases ˗ 3CLpro and PLpro, two of the most important pharmacological targets for antiviral development. Phenyleth
Externí odkaz:
https://doaj.org/article/8b9bf6f1f66e4faba555ee0fa6025112
Autor:
Mariacaterina Lianza, Ferruccio Poli, Alan Menezes do Nascimento, Aline Soares da Silva, Thamirys Silva da Fonseca, Marcos Vinicius Toledo, Rosineide Costa Simas, Andréa Rodrigues Chaves, Gilda Guimarães Leitão, Suzana Guimarães Leitão
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 554-562 (2022)
Aiming at finding natural sources of antidiabetics agents, 15 extracts from Brazilian medicinal plants of the Atlantic Forest and Amazon region were tested against α-glucosidase enzyme. Plants were selected based on the taxonomic relationships with
Externí odkaz:
https://doaj.org/article/6f085f78714d4611b4d55ee4ffb08270
Autor:
Daniele C. P. Rocha, Tháyna Sisnande, Daniel Gavino-Leopoldino, Iris Paula Guimarães-Andrade, Fernanda F. Cruz, Iranaia Assunção-Miranda, Simony C. Mendonça, Gilda Guimarães Leitão, Rosineide Costa Simas, Ronaldo Mohana-Borges, Suzana Guimarães Leitão, Diego Allonso
Publikováno v:
Viruses, Vol 15, Iss 11, p 2232 (2023)
Chikungunya fever, a debilitating disease caused by Chikungunya virus (CHIKV), is characterized by a high fever of sudden onset and an intense arthralgia that impairs individual regular activities. Although most symptoms are self-limited, long-term p
Externí odkaz:
https://doaj.org/article/05489966169747b5bc85d1a201d24c72
Autor:
Mariana Freire Campos, Simony Carvalho Mendonça, Evelyn Maribel Condori Peñaloza, Beatriz A. C. de Oliveira, Alice S. Rosa, Gilda Guimarães Leitão, Amanda R. Tucci, Vivian Neuza S. Ferreira, Thamara Kelcya F. Oliveira, Milene Dias Miranda, Diego Allonso, Suzana Guimarães Leitão
Publikováno v:
Molecules, Vol 28, Iss 7, p 3159 (2023)
Traditional medicine shows several treatment protocols for COVID-19 based on natural products, revealing its potential as a possible source of anti-SARS-CoV-2 agents. Ampelozizyphus amazonicus is popularly used in the Brazilian Amazon as a fortifier
Externí odkaz:
https://doaj.org/article/f6d1bf7aa0124d2b86a1a98f7b5d5ebb
Autor:
Wilmer H. Perera, Alexander M. Scherbakov, Galina I. Buravchenko, Ekaterina I. Mikhaevich, Suzana Guimarães Leitão, Paul Cos, Andrey E. Shchekotikhin, Lianet Monzote, William N. Setzer
Publikováno v:
Molecules, Vol 27, Iss 6, p 1926 (2022)
In this study, the in vitro antimicrobial, antiparasitic, antiproliferative and cytotoxic activities of essential oil from Baccharis parvidentata Malag. (EO-Bp) and Lippia origanoides Kunth (EO-Lo) were explored. The relevant effects were observed ag
Externí odkaz:
https://doaj.org/article/ba580ba8a1734980b11f838a40557cd0
Autor:
Carla Monteiro Leal, Suzana Guimarães Leitão, Leonardo Luiz Oliveira de Mello, Isabel de Castro Rangel, Carlos Vinicius Azevedo da Silva, Milene Dias Miranda, Amanda Resende Tucci, Camilla Blanco de Assis, Carolina de Queiroz Sacramento, Natalia Fintelman-Rodrigues, Hector Henrique Ferreira Koolen, Boniek Gontijo Vaz, Rosineide Costa Simas, Gilda Guimarães Leitão
Publikováno v:
Molecules, Vol 27, Iss 2, p 399 (2022)
Siparuna glycycarpa occurs in the Amazon region, and some species of this genus are used in Brazilian folk medicine. A recent study showed the inhibitory effect of this species against influenza A(H1N1)pdm09 virus, and in order to acquire active frac
Externí odkaz:
https://doaj.org/article/994e43e061c447f096b8a12b70d1b69c
Publikováno v:
Plants, Vol 11, Iss 2, p 191 (2022)
The Amazon Forest is known all over the world for its diversity and exuberance, and for sheltering several indigenous groups and other traditional communities. There, as well as in several other countries, in traditional medical systems, weakness, fa
Externí odkaz:
https://doaj.org/article/f5808aedb8cb443cb1066a39fd317957