Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Suzana A. Kahn"'
Autor:
Suzana A. Kahn, Xin Wang, Ryan T. Nitta, Sharareh Gholamin, Johanna Theruvath, Gregor Hutter, Tej D. Azad, Lina Wadi, Sara Bolin, Vijay Ramaswamy, Rogelio Esparza, Kun-Wei Liu, Michael Edwards, Fredrik J. Swartling, Debashis Sahoo, Gordon Li, Robert J. Wechsler-Reya, Jüri Reimand, Yoon-Jae Cho, Michael D. Taylor, Irving L. Weissman, Siddhartha S. Mitra, Samuel H. Cheshier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Group 3 medulloblastoma is an aggressive pediatric brain tumour that disseminates through the leptomeningeal cerebral spinal fluid. Here, the authors show that in Group 3 medulloblastoma NOTCH1 activates BMI1 through the activation of TWIST1, driving
Externí odkaz:
https://doaj.org/article/f343b2e492454377a5d248f3fe9493fb
Autor:
Suzana A. Kahn, Xin Wang, Ryan T. Nitta, Sharareh Gholamin, Johanna Theruvath, Gregor Hutter, Tej D. Azad, Lina Wadi, Sara Bolin, Vijay Ramaswamy, Rogelio Esparza, Kun-Wei Liu, Michael Edwards, Fredrik J. Swartling, Debashis Sahoo, Gordon Li, Robert J. Wechsler-Reya, Jüri Reimand, Yoon-Jae Cho, Michael D. Taylor, Irving L. Weissman, Siddhartha S. Mitra, Samuel H. Cheshier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article omitted Suzana A. Kahn, Siddhartha S. Mitra & Samuel H. Cheshier as jointly supervising authors. This has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/718607d8ff824d60adb0b16edaed753b
Autor:
Suzana Assad Kahn, Silvia Lima Costa, Sharareh Gholamin, Ryan T Nitta, Luiz Gustavo Dubois, Marie Fève, Maria Zeniou, Paulo Lucas Cerqueira Coelho, Elias El‐Habr, Josette Cadusseau, Pascale Varlet, Siddhartha S Mitra, Bertrand Devaux, Marie‐Claude Kilhoffer, Samuel H Cheshier, Vivaldo Moura‐Neto, Jacques Haiech, Marie‐Pierre Junier, Hervé Chneiweiss
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 5, Pp 511-526 (2016)
Abstract A variety of drugs targeting monoamine receptors are routinely used in human pharmacology. We assessed the effect of these drugs on the viability of tumor‐initiating cells isolated from patients with glioblastoma. Among the drugs targeting
Externí odkaz:
https://doaj.org/article/e0c2de418b164543ac5b7d7885f022cd
Autor:
Amanda Dos Santos Cavalcanti, Walter Meohas, Gabriele de Oliveira Ribeiro, Ana Cristina de Sá Lopes, Sharareh Gholamin, Mostafa Razavi, Taís Hanae Kasai Brunswick, Amir Avan, João Antonio Matheus Guimarães, Maria Eugenia Leite Duarte, Suzana Assad Kahn
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184891 (2017)
Osteosarcoma is the most common primary bone tumor in children and young adults. The median survival of osteosarcoma patients has not significantly improved since 1990, despite administration of different classes of chemotherapy agents, such as metho
Externí odkaz:
https://doaj.org/article/677ee0b6987d4e578effe6de756668a0
Autor:
Michael Zhang, Gregor Hutter, Suzana A Kahn, Tej D Azad, Sharareh Gholamin, Chelsea Y Xu, Jie Liu, Achal S Achrol, Chase Richard, Pia Sommerkamp, Matthew Kenneth Schoen, Melissa N McCracken, Ravi Majeti, Irving Weissman, Siddhartha S Mitra, Samuel H Cheshier
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153550 (2016)
Tumor-associated macrophages (TAMs) represent an important cellular subset within the glioblastoma (WHO grade IV) microenvironment and are a potential therapeutic target. TAMs display a continuum of different polarization states between antitumorigen
Externí odkaz:
https://doaj.org/article/c25227bd858d4ee192c10a749e29674d
Autor:
Maria Zeniou, Marie Fève, Samir Mameri, Jihu Dong, Christophe Salomé, Wanyin Chen, Elias A El-Habr, Fanny Bousson, Mohamadou Sy, Julie Obszynski, Alexandre Boh, Pascal Villa, Suzana Assad Kahn, Bruno Didier, Dominique Bagnard, Marie-Pierre Junier, Hervé Chneiweiss, Jacques Haiech, Marcel Hibert, Marie-Claude Kilhoffer
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134793 (2015)
Cancer stem-like cells reside in hypoxic and slightly acidic tumor niches. Such microenvironments favor more aggressive undifferentiated phenotypes and a slow growing "quiescent state" which preserves them from chemotherapeutic agents that essentiall
Externí odkaz:
https://doaj.org/article/156722edabe1482bb542a356e8277dd4
Autor:
Luiz Gustavo eDubois, Loraine eCampanati, Cassia eRighy, Isabella eD'Andrea-Meira, Tania Cristina Leite De Sampaio e Spohr, Isabel ePorto-Carreiro, Cláudia Maria Pereira, Joana eBalça-Silva, Suzana Assad Kahn, Marcos F. DosSantos, Marcela de Almeida Rabello Oliveira, Adriana eXimenes-da-Silva, Maria Celeste Lopes, Eduardo eFaveret, Emerson eGasparetto, Vivaldo eMoura-Neto
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 8 (2014)
Astrocytes, members of the glial family, interact through the exchange of soluble factors or by directly contacting neurons and other brain cells, such as microglia and endothelial cells. Astrocytic projections interact with vessels and act as additi
Externí odkaz:
https://doaj.org/article/034fae43872f416987c17a02dc236d19
Autor:
Siddhartha Mitra, Maryam N Shahin, Edward E. Graves, Marjan Rafat, Samuel H. Cheshier, Suzana Assad Kahn, Sharareh Gholamin, Amato J. Giaccia, Osama A. Youssef, Rogelio Esparza, Irving L. Weissman
Publikováno v:
Innate Immunity
Innate Immunity, Vol 26 (2020)
Innate Immunity, Vol 26 (2020)
Irradiation and temozolomide (TMZ) chemotherapy are the current standard treatments for glioblastoma multiforme (GBM), but they are associated with toxicity and limited efficacy. Recently, these standard therapies have been used to enhance immunother
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f507e9f5f58815370cc92a6cfcd98e6
https://doi.org/10.1177/1753425919876690
https://doi.org/10.1177/1753425919876690
Autor:
Maricruz Aurelia Fun Sang Cepeda, Jean-David Caprace, Newton Narciso Pereira, Suzana Assad Kahn
Publikováno v:
Marine Systems & Ocean Technology. 14:75-84
Maritime transport is responsible for about 2.5% of global greenhouse gas emissions representing around 1000 million tons of CO $$_2$$ annually. The situation of shipping emissions that strongly depends on future economic grows is aggravated by the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a35fd91b0b673403e8cad66783cb996
https://doi.org/10.1007/s40868-019-00059-y
https://doi.org/10.1007/s40868-019-00059-y
Autor:
Suzana Assad Kahn, Lifeng Lao, Haijun Tian, Jeffrey C. Wang, Ziyue Jiang, Jie Zhao, Elsa J. Brochmann, Chenshuang Li, Maria Eugenia Leite Duarte, Michael D. Daubs, Samuel S. Murray, Zorica Buser, Hongfang Chen, Tangjun Zhou
Publikováno v:
Journal of Orthopaedic Research. 37:1638-1648
The correlation between BMP-2 and osteosarcoma growth has gained increased interest in the recent years, however, there is still no consensus. In this study, we tested the effects of BMP-2 on osteosarcoma cells through both in vitro and in vivo exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb222aa50e199650faf2b88df475e8c
https://doi.org/10.1002/jor.24244
https://doi.org/10.1002/jor.24244