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hGBP-1 Expression Predicts Shorter Progression-Free Survival in Ovarian Cancers, While Contributing to Paclitaxel Resistance

Autor: Suzan Wadi, Deborah J. Vestal, Aaron R. Tipton, Jill A. Trendel, Sadik A. Khuder

Publikováno v: Journal of cancer therapy

Ovarian cancer is the gynecological cancer with the poorest prognosis. One significant reason is the development of resistance to the chemotherapeutic drugs used in its treatment. The large GTPase, hGBP-1, has been implicated in paclitaxel resistance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09923ef46a819478976f6a54a5cc1c74
https://pubmed.ncbi.nlm.nih.gov/28090373

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Guanylate-Binding Protein-1 protects ovarian cancer cell lines but not breast cancer cell lines from killing by paclitaxel

Autor: John P. Wilson, Geoffrey O. Nyabuto, Travis Mazur, Aaron R. Tipton, Jacob S. Justinger, Deborah J. Vestal, Jill A. Trendel, Peter T. Nguyen, Suzan Wadi, Garret L. Moore

Forced expression of the cytokine-induced large GTPase, human Guanylate-Binding Protein-1 (hGBP-1), in ovarian cancer cell lines increases resistance to paclitaxel. Elevated hGBP-1 RNA in ovarian tumors correlates with shorter recurrence-free surviva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cfa0aaa6cee7b2e464c73e6c434a08b
https://europepmc.org/articles/PMC5030188/

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Molecular, antibiogram and serological typing of Staphylococcus aureus isolates recovered from Al-Makased hospital in East Jerusalem

Autor: Anwar Doudin, Tamer Essawi, Ali Ibrahim Fattom, Tarek Nawas, Abbas Hawwari, Suzan Wadi

Publikováno v: Tropical Medicine and International Health. 3:576-583

Staphylococcus aureus is a major cause of nosocomial infections and a risk in patients who have either undergone surgery or are on haemodialysis. The S. aureus infections in patients admitted to the clinical departments of Al-Makased Charitable Hospi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee3f2d61f2187287a49cb70653a3ad02
https://doi.org/10.1046/j.1365-3156.1998.00265.x

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ID: 212

Autor: Sujata Balasubramanian, Angela F. Messmer-Blust, Suzan Wadi, Deborah J. Vestal

Publikováno v: Cytokine. 76:103

Guanylate-Binding Proteins (GBPs) are a family of pro-inflammatory cytokine-induced GTPases. These proteins have been best studied for their anti-microbial activities against pathogens sensitive to IFN- γ . However, GBPs have a number of significant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f810370b1ceae006861f1bc7b8bef8f6
https://doi.org/10.1016/j.cyto.2015.08.216

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