Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Suzan, Demuynck"'
Autor:
Marjolein Carron, Attila Placido Sachslehner, Munevver Burcu Cicekdal, Inge Bruggeman, Suzan Demuynck, Bahar Golabi, Elfride De Baere, Wim Declercq, Erwin Tschachler, Kris Vleminckx, Leopold Eckhart
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Cornified skin appendages, such as hair and nails, are major evolutionary innovations of terrestrial vertebrates. Human hair and nails consist largely of special intermediate filament proteins, known as hair keratins, which are expressed und
Externí odkaz:
https://doaj.org/article/a710d9a58fc84d2b8c16e5cff7cd038f
Autor:
Dieter, Tulkens, Dionysia, Dimitrakopoulou, Marthe, Boelens, Tom, Van Nieuwenhuysen, Suzan, Demuynck, Wendy, Toussaint, David, Creytens, Pieter, Van Vlierberghe, Kris, Vleminckx
Publikováno v:
Cancers. 14(19)
Modeling human genetic diseases and cancer in lab animals has been greatly aided by the emergence of genetic engineering tools such as TALENs and CRISPR/Cas9. We have previously demonstrated the ease with which genetically engineered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab72b7ffafb760f2baf667363ad3f76c
https://pubmed.ncbi.nlm.nih.gov/36230482
https://pubmed.ncbi.nlm.nih.gov/36230482
CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping
Autor:
Suzan Demuynck, Paul Coucke, Thomas Naert, David Creytens, Benjamin A. Alman, Christian Vanhove, Mushriq Al Jazrawe, Kim De Leeneer, Matt van de Rijn, Joanna Przybyl, Tom Van Nieuwenhuysen, Dieter Tulkens, Kris Vleminckx, Savvas N. Savvides
Publikováno v:
Proc Natl Acad Sci U S A
Cancer precision medicine implies identification of tumor-specific vulnerabilities associated with defined oncogenic pathways. Desmoid tumors are soft-tissue neoplasms strictly driven by Wnt signaling network hyperactivation. Despite this clearly def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8d0890ecc0d8dbd4516a2422f1fd77
https://doi.org/10.1073/pnas.2115116118
https://doi.org/10.1073/pnas.2115116118
Autor:
Dionysia Dimitrakopoulou, Kris Vleminckx, M. Boelens, P. Van Vlierberghe, David Creytens, Dieter Tulkens, Suzan Demuynck, T. Van Nieuwenhuysen, W. Toussaint
Modelling human genetic diseases and cancer in lab animals has been greatly aided by the emergence of genetic engineering tools such as TALENs and CRISPR/Cas9. We have previously demonstrated the ease with which genetically engineered Xenopus models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ce66f304303919ff66ebf3964fd6237
https://doi.org/10.1101/2021.11.15.468684
https://doi.org/10.1101/2021.11.15.468684
Autor:
Suzan Demuynck, Aaron M. Zorn, Kris Vleminckx, Marjolein Carron, Andy Willaert, Nicole A. Edwards, Marcin Wlizla, Thomas Naert, Dieter Tulkens, Paul Coucke, Annekatrien Boel, Nikko-Ideen Shaidani, Marko E. Horb
Publikováno v:
SCIENTIFIC REPORTS
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
CRISPR/Cas9 genome editing has revolutionized functional genomics in vertebrates. However, CRISPR/Cas9 edited F0 animals too often demonstrate variable phenotypic penetrance due to the mosaic nature of editing outcomes after double strand break (DSB)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462bc8461d063a25887d564380b7f954
https://doi.org/10.1038/s41598-020-71412-0
https://doi.org/10.1038/s41598-020-71412-0
Autor:
Dionysia Dimitrakopoulou, Liza Eeckhout, Kris Vleminckx, Christian Vanhove, Rivka Noelanders, Jo Van Dorpe, Gert Van Isterdael, Dieter Tulkens, Suzan Demuynck, Marjolein Carron, Dieter Deforce, Thomas Naert, David Creytens
Publikováno v:
Oncogene. 39(13)
Alterations of the retinoblastoma and/or the p53 signaling network are associated with specific cancers such as high-grade astrocytoma/glioblastoma, small-cell lung cancer (SCLC), choroid plexus tumors, and small-cell pancreatic neuroendocrine carcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0e6a50d81baaa4f3994202df0effea
https://pubmed.ncbi.nlm.nih.gov/32001819
https://pubmed.ncbi.nlm.nih.gov/32001819
Autor:
Dieter Tulkens, Dionysia Dimitrakopoulou, Dieter Deforce, Kris Vleminckx, Christian Vanhove, Gert Van Isterdael, Rivka Noelanders, Jo Van Dorpe, Liza Eeckhout, Thomas Naert, David Creytens, Suzan Demuynck
Alterations of the retinoblastoma and/or the p53 signaling network are associated with specific cancers such as high-grade astrocytoma/glioblastoma, small cell lung cancer (SCLC), choroid plexus tumors and small-cell pancreatic neuroendocrine carcino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b344b31f5c68d3c86f054dba6a81c41f