Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Suyu, Shu"'
Autor:
Christopher Paustian, Patricia Taylor, Terrence Johnson, Min Xu, Nancy Ramirez, Kenneth S Rosenthal, Suyu Shu, Peter A Cohen, Brian J Czerniecki, Gary K Koski
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54804 (2013)
Strategically-paired Toll-like receptor (TLR) ligands induce a unique dendritic cell (DC) phenotype that polarizes Th1 responses. We therefore investigated pairing single TLR ligands with a non TLR-mediated danger signal to cooperatively induce disti
Externí odkaz:
https://doaj.org/article/c9e02311c7774134888c772a100bfb31
Publikováno v:
Interleukin-2 and Killer Cells in Cancer ISBN: 9781351073790
Interleukin-2 and Killer Cells in Cancer
Interleukin-2 and Killer Cells in Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51659d89cf27809a5120ceb73251b05f
https://doi.org/10.1201/9781351073790-13
https://doi.org/10.1201/9781351073790-13
Autor:
Rongxiu Zheng, Suyu Shu
Publikováno v:
Journal of Surgical Oncology. 103:550-554
Regional draining lymph nodes (LNs) play a pivotal role in initiating immune responses. However, the presence of metastases may compromise their normal immunological function. Preclinical studies indicate that despite metastases, early tumor-draining
Publikováno v:
Head & Neck. 32:700-707
Background The aim of the present study was to evaluate the therapeutic efficacy of dendritic cell (DC)–tumor fusion hybrids with Toll-like receptor (TLR) agonists. Methods DC–tumor fusion hybrids were generated by electrofusion and injected into
Autor:
Suyu Shu, Katsuya Deguchi, Hidemasa Tamai, Li-Xin Wang, Rongxiu Zheng, Peter A. Cohen, Satoshi Watanabe
Publikováno v:
The Journal of Immunology. 181:3291-3300
Suppression of tumor-specific T cell sensitization is a predominant mechanism of tumor escape. To identify tumor-induced suppressor cells, we transferred spleen cells from mice bearing progressive MCA205 sarcoma into sublethally irradiated mice. Thes
Autor:
Gary K. Koski, Peter A. Cohen, Hidemasa Tamai, Katsuya Deguchi, Suyu Shu, Rongxiu Zheng, Satoshi Watanabe
Publikováno v:
Clinical Immunology. 127:66-77
Curative immunotherapy against spontaneous metastases of poorly immunogenic tumors has been difficult to demonstrate, but it is highly relevant to clinical disease conditions. The 4T1 mammary carcinoma shares many characteristics of human mammary can
Autor:
Rongxiu Zheng, Hidemasa Tamai, Hong-Ming Hu, Satoshi Watanabe, H Kuriyama, Peter A. Cohen, Gregory E. Plautz, Jorgen Kjaergaard, Suyu Shu, Andrew D. Weinberg
Publikováno v:
Cellular Immunology. 243:30-40
Dendritic-tumor heterokaryons generated by electrofusion are highly immunogenic. In animal studies, a single vaccination was therapeutic for tumors established in the lung, skin, and brain. However, effective therapy required a third signal which cou
Autor:
Marshall Strome, Samir S. Khariwala, Frederick Van Lente, Robert R. Lorenz, Jorgen Kjaergaard, Suyu Shu
Publikováno v:
The Laryngoscope. 116:814-820
Objective: Everolimus (RAD) is an mTOR inhibitor closely related to rapamycin. A potent immunosuppressive agent, it has also shown evidence of antineoplastic properties. SCC VII is a spontaneously arising murine squamous cell carcinoma line. This stu
Publikováno v:
Otolaryngology–Head and Neck Surgery. 132:755-764
Objective To establish the basis for use of allogeneic dendritic-tumor fusion cells. Study design Fusion cells were created by electrofusion. We used 2 allogeneic murine tumor lines (D5 and 4T1) that were virally transduced to express the antigen (β
Publikováno v:
Journal of Immunotherapy. 27:265-272
Dendritic cells (DCs) loaded with antigens can effectively stimulate host immune responses to syngeneic tumors, but there is considerable controversy as to which forms of antigen-loading are most immunogenic. Here, the authors compared immunotherapeu