Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Suyog Pol"'
Autor:
Claire M Modica, Ferdinand Schweser, Michelle L Sudyn, Nicola Bertolino, Marilena Preda, Paul Polak, Danielle M Siebert, Jacqueline C Krawiecki, Michele Sveinsson, Jesper Hagemeier, Michael G Dwyer, Suyog Pol, Robert Zivadinov
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182729 (2017)
Pathology of gray matter is associated with development of physical and cognitive disability in patients with multiple sclerosis. In particular, glutamatergic dysregulation in the cortex-basal ganglia-thalamus (CxBGTh) circuit could be associated wit
Externí odkaz:
https://doaj.org/article/19a66a2f09514348bed115a0b088defc
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5700 (2009)
BACKGROUND: Proteases play a central role in cellular homeostasis and are responsible for the spatio-temporal regulation of function. Many putative proteases have been recently identified through genomic approaches, leading to a surge in global profi
Externí odkaz:
https://doaj.org/article/988ca0d2b8ab44998fe15df47e0d3a41
Background Ibrutinib, a Bruton Tyrosine Kinase inhibitor (iBTK), binds with target protein to arrest B-cell development and decrease microglia activation. Considering the emerging role of B and microglial cells in multiple sclerosis (MS) pathology, B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c6f0543256ffd93089f48f07e01f3f3
https://doi.org/10.21203/rs.3.rs-2090036/v1
https://doi.org/10.21203/rs.3.rs-2090036/v1
Publikováno v:
Journal of Neuroimaging. 30:769-778
BACKGROUND AND PURPOSE Blood-derived monocytes/macrophages can be labeled with ultrasmall superparamagnetic iron oxides (USPIO) at periphery and subsequently migrate into areas of inflammation in the brain. We investigated temporal pattern of migrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd342cc39bae1296db9d3cd4448341c
https://doi.org/10.1111/jon.12768
https://doi.org/10.1111/jon.12768
Autor:
Jacqueline E. Broome, Ajai Tripathi, Fraser J. Sim, Darpan Saraswat, Suyog Pol, Ranjan Dutta, R. Ross Welliver, Melanie A. O'Bara, Hani J. Shayya, Jessie J. Polanco, Richard A. Seidman, Joanna J. Phillips, Toin H. van Kuppervelt
Publikováno v:
Nature communications, vol 12, iss 1
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Chronic demyelination in the human CNS is characterized by an inhibitory microenvironment that impairs recruitment and differentiation of oligodendrocyte progenitor cells (OPCs) leading to failed remyelination and axonal atrophy. By network-based tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd869a845f4787f2e1d1c13a69c255d
https://doi.org/10.1038/s41467-021-22263-4
https://doi.org/10.1038/s41467-021-22263-4
Autor:
Suyog Pol, Nicola Bertolino, Robert Zivadinov, Marilena Preda, Claire M. Modica, Michele Sveinsson, Danielle Siebert, Natan Babek, Michelle Sudyn, Ferdinand Schweser
Publikováno v:
Journal of Neuroimaging. 29:52-61
BACKGROUND AND PURPOSE Teriflunomide reduces disability progression and brain atrophy in multiple sclerosis patients. The exact mechanism of action by which teriflunomide exerts these effects is currently unknown. We assessed the effect of teriflunom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cce5dfc8348848b01b98c91f0a121c50
https://doi.org/10.1111/jon.12561
https://doi.org/10.1111/jon.12561
Autor:
Karen C. Dietz, Jessie J. Polanco, Richard A. Seidman, Suyog Pol, Fraser J. Sim, Melanie A. O'Bara, Hani J. Shayya
Publikováno v:
Stem Cell Reports, Vol 9, Iss 2, Pp 710-723 (2017)
Stem Cell Reports
Stem Cell Reports
Summary Impaired human oligodendrocyte progenitor cell (hOPC) differentiation likely contributes to failed remyelination in multiple sclerosis. The characterization of molecular pathways that regulate hOPC differentiation will provide means to induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03abbb9349bd294ea1928a90199edc0
http://www.sciencedirect.com/science/article/pii/S221367111730317X
http://www.sciencedirect.com/science/article/pii/S221367111730317X
Autor:
Deepa P. Ramasamy, Gisbert Weckbecker, Marilena Preda, Serena Liang, Ravendra Dhanraj, Michele Sveinsson, Michael G. Dwyer, Suyog Pol, Robert Zivadinov, Anna Schubart, Ferdinand Schweser
Publikováno v:
Experimental Neurology. 335:113488
Background The human myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis (huMOG-EAE) model, generates B-cell driven demyelination in mice, making it a suitable multiple sclerosis model to study B cell depletion. Obje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5093a9a1e067acf48998980b24083d4b
https://doi.org/10.1016/j.expneurol.2020.113488
https://doi.org/10.1016/j.expneurol.2020.113488
Autor:
Michele Sveinsson, Natan Babek, Marilena Preda, Suyog Pol, Nicola Bertolino, Ferdinand Schweser, Robert Zivadinov, Michelle Sudyn
Publikováno v:
Experimental neurology. 314
Background Leptomeningeal inflammation, as evidenced by leptomeningeal contrast enhancement (LMCE), is associated to cortical pathology in multiple sclerosis. The temporal pattern of LMCE in experimental autoimmune encephalomyelitis (EAE) myelin olig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a4b1924bbcceee9b14e04b32598f07
https://pubmed.ncbi.nlm.nih.gov/30684521
https://pubmed.ncbi.nlm.nih.gov/30684521
Autor:
Thomas R. Cimato, Fraser J. Sim, Melanie A. O'Bara, Jennifer K Lang, Andrew S. McCallion, Suyog Pol
Publikováno v:
Experimental Neurology. 247:694-702
In this study, we sought to establish a novel method to prospectively and dynamically identify live human oligodendrocyte precursor cells (OPCs) and oligodendrocyte lineage cells from brain dissociates and pluripotent stem cell culture. We selected a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb458b2fccdb3b62b93e265995a0233
https://doi.org/10.1016/j.expneurol.2013.03.010
https://doi.org/10.1016/j.expneurol.2013.03.010