Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Suyog M. Amrutkar"'
Autor:
Anmada Nayak, Sankar K. Guchhait, Garima Priyadarshani, Uttam Chand Banerjee, Suyog M. Amrutkar, Chanakya Nath Kundu, Sarita Das
Publikováno v:
ACS Medicinal Chemistry Letters. 7:1056-1061
Scaffold-hopping of bioactive natural product aurones has been studied for the first time. 2-Arylideneimidazo[1,2-a]pyridinones as potential topoisomerase IIα (hTopoIIα)-targeting anticancer compounds were considered. A multifunctional activator, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a091ae51eec18748f40c31a30849df8
https://doi.org/10.1021/acsmedchemlett.6b00242
https://doi.org/10.1021/acsmedchemlett.6b00242
Autor:
Darpan Darpan, Ashish T. Baviskar, Sandeep Singh, Harveen Kler, Uttam Chand Banerjee, Gaurav Joshi, Raj Kumar, Suyog M. Amrutkar
Publikováno v:
RSC Advances. 6:14880-14892
Based on reported pharmacophores as topoisomerase inhibitors, 2,5-dimethylthiophene/furan based N-acetyl pyrazolines were designed and envisaged as topoisomerase inhibitors. The target compounds were synthesized and tested in vitro against human topo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dba6ea8218927675d1d9322011904a0
https://doi.org/10.1039/c5ra25705k
https://doi.org/10.1039/c5ra25705k
Autor:
Praveen Sharma, Monika Chauhan, Suyog M. Amrutkar, Raj Kumar, Harveen Kler, Sandeep Singh, Uttam Chand Banerjee, Archana Kashyap, Gaurav Joshi, Kiran D. Bhilare
Publikováno v:
RSC Advances. 6:77717-77734
Based on the quinazoline bearing EGFR inhibitors, a series of thirty four compounds having a quinoline scaffold were synthesised and evaluated in vitro for EGFR kinase inhibitory activity. A structure–activity relationship study revealed that 2,4-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0ff3b41a27f323e7d2c58130f5c7c1e
https://doi.org/10.1039/c6ra15118c
https://doi.org/10.1039/c6ra15118c
Autor:
Santosh Kumar, Sadhana Sharma, Arshad J. Ansari, Uttam Chand Banerjee, Devesh M. Sawant, Ashoke Sharon, Gaurav Joshi, Sandeep Singh, Sourav Kalra, Suyog M. Amrutkar, Umesh Prasad Yadav, Raj Kumar, Praveen Sharma, Pankaj Kumar Singh
Publikováno v:
Bioorganic Chemistry. 94:103409
In the quest to ameliorate the camptothecin (CPT) downsides, we expedite to search for stable non-CPT analogues among 11 motifs of pyrazoloquinazolines reported. E-pharmacophore drug design approach helped filtering out pyrazolo[1,5-c]quinazolines as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d03daf3dc40a42ecf8f58fc36a0e15a7
https://doi.org/10.1016/j.bioorg.2019.103409
https://doi.org/10.1016/j.bioorg.2019.103409
Publikováno v:
Tetrahedron Letters. 54:3274-3277
R)-1-(1-Naphthyl)ethanol is an essential chiral substrate for the synthesis of nonactin and dihydro-(1H)- quinoline-2-one derivatives. Stereoinversion of (S)-1-(1-naphthyl)ethanol to (R)-1-(1-naphthyl)ethanol by whole cell biocatalysis, using Candida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85d21492f96fe6b46b2718b4ca2f49ee
https://doi.org/10.1016/j.tetlet.2013.04.051
https://doi.org/10.1016/j.tetlet.2013.04.051
Autor:
Garima, Priyadarshani, Anmada, Nayak, Suyog M, Amrutkar, Sarita, Das, Sankar K, Guchhait, Chanakya N, Kundu, Uttam C, Banerjee
Publikováno v:
ACS medicinal chemistry letters. 7(12)
Scaffold-hopping of bioactive natural product aurones has been studied for the first time. 2-Arylideneimidazo[1,2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5edf11362811e0f0080656dc9e49464a
https://pubmed.ncbi.nlm.nih.gov/27994737
https://pubmed.ncbi.nlm.nih.gov/27994737
Autor:
Sourav Kalra, Gaurav Joshi, Anil K. Mantha, Gagandeep Kaur, Ravi P. Cholia, Suyog M. Amrutkar, Raj Kumar, Uttam Chand Banerjee
Publikováno v:
Archiv der Pharmazie. 351:1800023
The design and synthesis of dihydropyrazolo[1,5-c]quinazolines (1a-h) as human topoisomerase II (TopoII) catalytic inhibitors are reported. The compounds were investigated for their antiproliferative activity against the C6 rat glial cell line. Two c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ea29f04de36835cda2eeb08a0c6b93
https://doi.org/10.1002/ardp.201800023
https://doi.org/10.1002/ardp.201800023
Autor:
Arvind Negi, Sandeep Singh, Jimi Marin Alex, Ashish T. Baviskar, Gaurav Joshi, Uttam Chand Banerjee, Suyog M. Amrutkar, Raj Kumar
Publikováno v:
Bioorganicmedicinal chemistry. 23(17)
Microwave-accelerated synthesis and anticancer activity of novel imine/amide–imidazole conjugates derived from 5-amino-4-cyano- N 1-substituted benzyl imidazole against a panel of seven cancer cell lines are reported for the first time. Compounds A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826fd6cfed9601d456da40e1c23dd8f5
https://pubmed.ncbi.nlm.nih.gov/26216018
https://pubmed.ncbi.nlm.nih.gov/26216018
Autor:
Sankar K. Guchhait, Neha Trivedi, Vikas Chaudhary, Chanakya Nath Kundu, Uttam Chand Banerjee, Ashish T. Baviskar, Anmada Nayak, Prasad V. Bharatam, Suyog M. Amrutkar
Publikováno v:
ACS medicinal chemistry letters. 6(4)
A study of structure-based modulation of known ligands of hTopoIIα, an important enzyme involved in DNA processes, coupled with synthesis and in vitro assays led to the establishment of a strategy of rational switch in mode of inhibition of the enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f23c4cde915097cd771ed0140a1a4f
https://pubmed.ncbi.nlm.nih.gov/25941559
https://pubmed.ncbi.nlm.nih.gov/25941559