Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear.

Autor: Hrdinova J; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6200 MD Maastricht, The Netherlands.; Department of Molecular and Cellular Hemostasis, Sanquin-Academic Medical Center, 1011 LZ Amsterdam, The Netherlands., Fernández DI; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6200 MD Maastricht, The Netherlands.; Platelet Proteomics Group, Center for Research in Molecule Medicine and Chronic Diseases (CiMUS), Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain., Ercig B; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6200 MD Maastricht, The Netherlands.; Department of Molecular and Cellular Hemostasis, Sanquin-Academic Medical Center, 1011 LZ Amsterdam, The Netherlands., Tullemans BME; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6200 MD Maastricht, The Netherlands., Suylen DPL; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6200 MD Maastricht, The Netherlands., Agten SM; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6200 MD Maastricht, The Netherlands., Jurk K; Center for Thrombosis and Hemostasis (CTH), University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Hackeng TM; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6200 MD Maastricht, The Netherlands., Vanhoorelbeke K; Laboratory for Thrombosis Research, Interdisciplinary Research Facility Life Sciences, Katholieke Universiteit Leuven Campus Kulak Kortrijk, 8500 Kortrijk, Belgium., Voorberg J; Department of Molecular and Cellular Hemostasis, Sanquin-Academic Medical Center, 1011 LZ Amsterdam, The Netherlands., Reutelingsperger CPM; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6200 MD Maastricht, The Netherlands., Wichapong K; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6200 MD Maastricht, The Netherlands., Heemskerk JWM; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6200 MD Maastricht, The Netherlands.; Synapse Research Institute, Kon. Emmaplein 7, 6214 AC Maastricht, The Netherlands., Nicolaes GAF; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6200 MD Maastricht, The Netherlands.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Feb 12; Vol. 23 (4). Date of Electronic Publication: 2022 Feb 12.

Design and synthesis of a multivalent catch-and-release assay to measure circulating FXIa.

Autor: van der Beelen SHE; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands., Agten SM; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands., Suylen DPL; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands., Wichapong K; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands., Hrdinova J; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands., Mees BME; Vascular Surgery, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands., Spronk HMH; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands; Internal Medicine, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands., Hackeng TM; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, the Netherlands. Electronic address: t.hackeng@maastrichtuniversity.nl.

Publikováno v: Thrombosis research [Thromb Res] 2021 Apr; Vol. 200, pp. 16-22. Date of Electronic Publication: 2021 Jan 18.

Platelet-derived extracellular vesicles play an important role in platelet transfusion therapy.

Autor: Zhi Cai¹, Junyan Feng², Nian Dong³, Pan Zhou⁴ zpan200507@163.com, Yuanshuai Huang¹ hys@live.cn, Hongwei Zhang¹ zhanghongwei2020@swmu.edu.cn

Publikováno v: Platelets. Dec2023, Vol. 34 Issue 1, p1-11. 11p.

The integrin beta1 modulator Tirofiban prevents adipogenesis and obesity by the overexpression of integrin-linked kinase: a pre-clinical approach in vitro and in vivo.

Autor: de Frutos, S.^1,2,3,4 (AUTHOR) sergio.frutos@uah.es, Griera, M.^1,2,3 (AUTHOR), Hatem-Vaquero, M.^1,2 (AUTHOR), Campillo, S.^1,2 (AUTHOR), Gutiérrez-Calabres, E.^1,2 (AUTHOR), García-Ayuso, D.^1,2 (AUTHOR), Pardo, M.⁵ (AUTHOR), Calleros, L.^1,2 (AUTHOR), Rodríguez-Puyol, M.^1,2 (AUTHOR), Rodríguez-Puyol, D.^2,4,6 (AUTHOR)

Publikováno v: Cell & Bioscience. 1/28/2022, Vol. 12 Issue 1, p1-18. 18p.

Antiplatelet Activity of Piper cubeba Fruit Ethanol Extract.

Autor: Herlyanti, Kyky, Murwanti, Retno, Wahyono, Fakhrudin, Nanang

Publikováno v: Tropical Journal of Natural Product Research; Nov2022, Vol. 6 Issue 11, p1832-1835, 4p