Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Suying Dang"'
Autor:
Liya Wang, Li He, Weijia Yi, Min Wang, Fangmin Xu, Hanlin Liu, Jiahui Nie, Yi-Hsuan Pan, Suying Dang, Wei Zhang
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110273- (2024)
Summary: Liver sinusoidal endothelial cells (LSECs) have a unique morphological structure known as “fenestra” that plays a crucial role in liver substance exchange and homeostasis maintenance. In this study, we demonstrate that ADAMTS18 protease
Externí odkaz:
https://doaj.org/article/90e9a500ec904383bed7cdb288dafb93
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-14 (2024)
Abstract Background Human epidermal growth factor receptor 2 (HER2)-positive breast cancer accounts for about 20% of all breast cancer cases and is correlated with a high relapse rate and poor prognosis. ADAMTS18 is proposed as an important functiona
Externí odkaz:
https://doaj.org/article/fd68a36e74bc46e789ca2a48fd0d6c03
Autor:
Shuai Ye, Ning Yang, Tiantian Lu, Taojing Wu, Liya Wang, Yi-Hsuan Pan, Xiaohua Cao, Xiaobing Yuan, Thomas Wisniewski, Suying Dang, Wei Zhang
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102672- (2021)
Summary: Members of a disintegrin and metalloproteinases with thrombospondin motif (ADAMTS) family have been implicated in various vascular diseases. However, their functional roles in early embryonic vascular development are unknown. In this study,
Externí odkaz:
https://doaj.org/article/1d83252bc1c5489cbdfbfac8008a90e7
Autor:
Tiantian Lu, Xiaotian Lin, Yi-Hsuan Pan, Ning Yang, Shuai Ye, Qi Zhang, Caiyun Wang, Rui Zhu, Tianhao Zhang, Thomas M. Wisniewski, Zhongwei Cao, Bi-Sen Ding, Suying Dang, Wei Zhang
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101472- (2020)
Summary: ADAMTSs (a disintegrin and metalloproteinase with thrombospondin motifs) are secreted metalloproteinases that play a major role in the assembly and degradation of the extracellular matrix (ECM). In this study, we show that ADAMTS18, produced
Externí odkaz:
https://doaj.org/article/8ce7ad43d9314d18873c1a99061677e1
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e27012 (2011)
Most antithrombotic approaches target prevention rather than the more clinically relevant issue of resolution of an existing thrombus. In this study, we describe a novel and effective therapeutic strategy for ex vivo clearance of pre-existing platele
Externí odkaz:
https://doaj.org/article/d985d1f122164587af61b5436568fc81
Autor:
M Sun, Tiantian Lu, Shuai Ye, Wei Zhang, Yi-Hsuan Pan, Qi Zhang, Min Wang, Liya Wang, Suying Dang, Ning Yang
Publikováno v:
Journal of Dental Research. 101:226-234
Chronic sclerosing sialadenitis of the submandibular gland (also known as Küttner tumor) is characterized by concomitant swelling of the submandibular glands secondary to strong lymphocytic infiltration and fibrosis. The pathogenesis of this disease
Publikováno v:
Experimental eye research. 218
ADAMTS18 is an orphan member of the ADAMTS family of metalloproteinase. ADAMTS18 mutation has been linked to developmental eye disorders, such as retinal dystrophies and ectopia lentis. Here, we report a new function of ADAMTS18 in modulating the lac
Autor:
Thomas Wisniewski, Suying Dang, Yi-Hsuan Pan, Liya Wang, Xiaobing Yuan, Xiaohua Cao, Taojing Wu, Ning Yang, Shuai Ye, Tiantian Lu, Wei Zhang
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102672-(2021)
iScience
iScience
Summary Members of a disintegrin and metalloproteinases with thrombospondin motif (ADAMTS) family have been implicated in various vascular diseases. However, their functional roles in early embryonic vascular development are unknown. In this study, w
Publikováno v:
Reproductive biology. 21(3)
ADAMTSs (A disintegrin and metalloproteinase with thrombospondin motifs) are a family of 19 secreted zinc metalloproteinases that play a major role in the assembly and degradation of the extracellular matrix (ECM) during development, morphogenesis, t
Autor:
Yi-Hsuan Pan, Taojing Wu, Tiantian Lu, Xiaobing Yuan, Thomas Wisniewski, Liya Wang, Suying Dang, Shuai Ye, Xiaohua Cao, Wei Zhang, Ning Yang
Publikováno v:
SSRN Electronic Journal.
ADAMTS members have been implicated in vascular diseases by degrading extracellular matrix (ECM), but their functional significance in vascular development remains unknown. We now show that the secreted protease ADAMTS18 is produced by mesenchymal ce