Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Suya Yang"'
Autor:
Luiz Belardinelli, Dmytro Kornyeyev, Jessie Jia, Lina Yao, Faquan Liang, Nikos Pagratis, Zhan Jiang, Suya Yang, Peidong Fan, Serge Karpinski
Publikováno v:
Journal of Molecular and Cellular Cardiology. 94:122-130
Increases in late Na(+) current (late INa) and activation of Ca(2+)/calmodulin-dependent protein kinase (CaMKII) are associated with atrial arrhythmias. CaMKII also phosphorylates Nav1.5, further increasing late INa. The combination of a CaMKII inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efdc9a105153c80c4a9eacfe79b5e108
https://doi.org/10.1016/j.yjmcc.2016.04.001
https://doi.org/10.1016/j.yjmcc.2016.04.001
Publikováno v:
Hypertension. 59:705-711
Endothelin receptor antagonists and phosphodiesterase type 5 inhibitors are used to treat pulmonary arterial hypertension. We tested the hypothesis that a selective endothelin type A receptor antagonist (ambrisentan) and a phosphodiesterase type 5 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d0eb051e7e91d577c9e8cefae75e42
https://doi.org/10.1161/hypertensionaha.111.182261
https://doi.org/10.1161/hypertensionaha.111.182261
Autor:
Nicholas F. Paoni, Ralph H. Schwall, Jo-Anne Hongo, Gladys Ingle, Constance H. Zlot, Suya Yang, Zhong Sheng, Mary E. Gerritsen, Franklin Peale, Fay Wang
Publikováno v:
Journal of Biological Chemistry. 278:47654-47659
Stanniocalcin 1 (STC1) is a secreted glycoprotein originally described as a hormone involved in calcium and phosphate homeostasis in bony fishes. We recently identified the mammalian homolog of this molecule to be highly up-regulated in an in vitro m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d0e6124eac5323d02d50e942123091
https://doi.org/10.1074/jbc.m301353200
https://doi.org/10.1074/jbc.m301353200
Publikováno v:
Proceedings of the National Academy of Sciences. 100:3374-3379
The human β-globin locus has been extensively studied as a model of tissue and developmental stage-specific gene expression. Structural mapping of naturally occurring mutations, including transfection and transgenic studies, and the recent finding o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bbcd4ffb626fa53d7950b3ee3d8838e
https://doi.org/10.1073/pnas.0634132100
https://doi.org/10.1073/pnas.0634132100
Autor:
Mary E. Gerritsen, Bing Li, P. Mickey Williams, Constance H. Zlot, Gladys Ingle, Karen Toy, Germaine Fuh, Suya Yang, Abraham M. de Vos
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 22:1797-1803
Objective— This study evaluated the relative roles of the vascular endothelial growth factor (VEGF) receptors KDR and Flt-1 in the mediation of altered gene expression elicited by VEGF. Methods and Results— We used mutants of VEGF selective for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2570bb2dec0cbb6133a08fe0c2716d66
https://doi.org/10.1161/01.atv.0000038995.31179.24
https://doi.org/10.1161/01.atv.0000038995.31179.24
Autor:
Franklin Peale, Constance H. Zlot, Robert Soriano, Jane Winer, Suya Yang, Gladys Ingle, Mary E. Gerritsen, P. Mickey Williams, Karen Toy, Thomas D. Wu, Aparna Draksharapu
Publikováno v:
Physiological Genomics. 10:13-20
The objective of this study was to use gene expression data from well-defined cell culture models, in combination with expression data from diagnostic samples of human diseased tissues, to identify potential therapeutic targets and markers of disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042b9e2ed888912bc236c7e882cc59ff
https://doi.org/10.1152/physiolgenomics.00035.2002
https://doi.org/10.1152/physiolgenomics.00035.2002
Autor:
Mary E. Gerritsen, Nazilla B. Alderson, Martin A. Schwartz, John Hood, Suya Yang, David A. Cheresh, William B. Kiosses
Publikováno v:
Circulation Research. 90:697-702
PAK1 is a protein kinase downstream of the small GTPases Rac and Cdc42 that previous work has implicated in endothelial cell migration via modulation of cell contraction. The first proline-rich region of PAK that binds to an SH3 domain from the adapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e195629e5ded36b53f7868be33feae0
https://doi.org/10.1161/01.res.0000014227.76102.5d
https://doi.org/10.1161/01.res.0000014227.76102.5d
Autor:
Gladys Ingle, Napoleone Ferrara, Joe Kowalski, Ralph H. Schwall, Mary E. Gerritsen, Xiaohua Xin, Constance H. Zlot, Suya Yang, Linda Rangell
Publikováno v:
The American Journal of Pathology. 158:1111-1120
Vascular endothelial growth factor (VEGF) is an important mediator of angiogenesis in both physiological and pathological processes. Hepatocyte growth factor (HGF) is a mesenchyme-derived mitogen that also stimulates cell migration, and branching and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db326e183daff7b2c4ce59cc180ada3
https://doi.org/10.1016/s0002-9440(10)64058-8
https://doi.org/10.1016/s0002-9440(10)64058-8
Publikováno v:
The American Journal of Pathology. 155:887-895
Various in vitro models have been described that emulate one or more of the processes involved in angiogenesis in vivo. In the present study endothelial cells were cultured in three-dimensional type I collagen lattices in the presence of a mixture of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c46aca44b699b944131c378044b31a4
https://doi.org/10.1016/s0002-9440(10)65188-7
https://doi.org/10.1016/s0002-9440(10)65188-7
Autor:
Ronghua Lu, Elaine J. Carlson, Michael Kitamura, Karin M.L. Gaensler, Linda Flebbe-Rehwaldt, Suya Yang, Judy C. Chang, Susanna Porcu, Yuet Wai Kan, Chin Lin, Shan-Mei Xu
Publikováno v:
Proceedings of the National Academy of Sciences. 95:14886-14890
Sickle cell anemia (SCA) and thalassemia are among the most common genetic diseases worldwide. Current approaches to the development of murine models of SCA involve the elimination of functional murine α- and β-globin genes and substitution with hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d66159e869ffd9a19f24181e5e9b605
https://doi.org/10.1073/pnas.95.25.14886
https://doi.org/10.1073/pnas.95.25.14886