Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Suya, Du"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Xenotransplantation has the potential to solve the shortfall of human organ donors. Genetically modified pigs have been considered as potential animal donors for human xenotransplantation and have been widely used in preclinical research. The genetic
Externí odkaz:
https://doaj.org/article/4318d21f7f344ee3b312fd42699c2c85
Autor:
Yilong Liu, Suya Du, Mengying Yuan, Xia He, Changyu Zhu, Ke Han, Yuyan Zhu, Qianwen Yang, Rongsheng Tong
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Ferroptosis has been implicated in tumor progression and immunoregulation. Identification of ferroptosis-related prognostic gene is important for immunotherapy and prognosis in ovarian cancer (OV). We assessed the potential predictive power of a nove
Externí odkaz:
https://doaj.org/article/07cdb51dec33425e91ab20da0e22c922
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Diabetes is a metabolic disease characterized by insulin deficiency. Bioengineering of stem cells with the aim to restore insulin production and glucose regulation has the potential to cure diabetic patients. In this review, we focus on the recent de
Externí odkaz:
https://doaj.org/article/6b90a8c0101f4d0a976d8c0a2061397d
Publikováno v:
International Journal of Molecular Medicine. 50
The repair of DNA double‑strand breaks (DSBs) is crucial for the preservation of genomic integrity and the maintenance of cellular homeostasis. Non‑homologous DNA end joining (NHEJ) is the predominant repair mechanism for any type of DNA DSB duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc8f9906c4c3935a47556409d45b7eee
https://doi.org/10.3892/ijmm.2022.5145
https://doi.org/10.3892/ijmm.2022.5145
Publikováno v:
Oncology Reports
Glycogen synthase kinase 3β (GSK 3β), a multifunctional serine and threonine kinase, plays a critical role in a variety of cellular activities, including signaling transduction, protein and glycogen metabolism, cell proliferation, cell differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b7e2eacd9968757c1ebc6d6d53b9d0
https://doi.org/10.3892/or.2020.7817
https://doi.org/10.3892/or.2020.7817
Publikováno v:
Oncotarget
Tumor cell metabolism is characterized by abundant glucose consumption and aerobic glycolysis. And pyruvate kinase M2 (PKM2) plays a decisive role in glycolysis, significantly contributing to the Warburg effect, tumor growth, angiogenesis, cell divis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba893a2c005cab4620e204b7772c3c7
http://europepmc.org/articles/PMC5746412
http://europepmc.org/articles/PMC5746412
Autor:
Suya Du, Yuping Liu, Dingding Zhang, Ting Liu, Tiantian Lei, Lea Girani, Dandan Qi, Yi Wang, Chen Lin, Rongsheng Tong
Publikováno v:
International Journal of Molecular Medicine
Necroptosis is a type of programmed cell death with necrotic morphology, occurring in a variety of biological processes, including inflammation, immune response, embryonic development and metabolic abnormalities. The current nomenclature defines necr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eecca55bc0dff2cac58ce2b4b4d83bd
https://doi.org/10.3892/ijmm.2019.4244
https://doi.org/10.3892/ijmm.2019.4244
Publikováno v:
Xenotransplantation. 26
The main obstacle to organ transplantation is the shortage of organs from deceased individuals. Especially in China, the ratio of patients on the waiting list versus the transplant recipients is 30:1. Therefore, there is an urgent need for organ dono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253ae0ce8b7834a5f337a07ff442a88e
https://doi.org/10.1111/xen.12490
https://doi.org/10.1111/xen.12490
Autor:
Xiang Li, Hailian Wang, Xia He, Tiantian Lei, Wenjing He, Yaodong You, Rongsheng Tong, Suya Du, Yi Wang
Publikováno v:
Oncology Letters
Ovarian cancer is the most malignant gynecologic neoplasm in women and has the worst prognosis of all cancer types in women based on the 5-year survival rates. A previous study indicated that mangiferin exerts an anti-neoplastic effect on human ovari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3227e27bf34d0b782b04058de9b24cd5
https://doi.org/10.3892/ol.2018.9708
https://doi.org/10.3892/ol.2018.9708
Publikováno v:
Oncology Reports
The Hippo pathway, initially identified through screenings for mutant tumor suppressors in Drosophila, is an evolutionarily conserved signaling pathway that controls organ size by regulating cell proliferation and apoptosis. Abnormal regulation of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c5f701a66f7649cd55e4ba07197171
https://doi.org/10.3892/or.2018.6423
https://doi.org/10.3892/or.2018.6423