Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Suvo Chatterjee"'
Autor:
Fasil Tekola-Ayele, Xuehuo Zeng, Suvo Chatterjee, Marion Ouidir, Corina Lesseur, Ke Hao, Jia Chen, Markos Tesfaye, Carmen J. Marsit, Tsegaselassie Workalemahu, Ronald Wapner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The placenta plays key roles in fetal development and subsequent health. Here, the authors integrate placental methylation and transcriptome data with genetic loci associated with birthweight to identify functional genes underpinning fetal growth reg
Externí odkaz:
https://doaj.org/article/05a453443d824438aa0e58dbc799f033
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Childhood obesity is a global public health problem. Understanding the molecular mechanisms that underlie early origins of childhood obesity can facilitate interventions. Consistent phenotypic and genetic correlations have been found between
Externí odkaz:
https://doaj.org/article/1d0aa73db1f74a0f9d4f7c5274df0079
Autor:
Himel Mallick, Ali Rahnavard, Lauren J McIver, Siyuan Ma, Yancong Zhang, Long H Nguyen, Timothy L Tickle, George Weingart, Boyu Ren, Emma H Schwager, Suvo Chatterjee, Kelsey N Thompson, Jeremy E Wilkinson, Ayshwarya Subramanian, Yiren Lu, Levi Waldron, Joseph N Paulson, Eric A Franzosa, Hector Corrada Bravo, Curtis Huttenhower
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 11, p e1009442 (2021)
It is challenging to associate features such as human health outcomes, diet, environmental conditions, or other metadata to microbial community measurements, due in part to their quantitative properties. Microbiome multi-omics are typically noisy, sp
Externí odkaz:
https://doaj.org/article/d5bfd901e9b34b5b917ec5de230898ee
Autor:
Marion Ouidir, Suvo Chatterjee, Pauline Mendola, Cuilin Zhang, Katherine. L. Grantz, Fasil Tekola-Ayele
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Maternal dyslipidemia during pregnancy has been associated with suboptimal fetal growth and increased cardiometabolic diseasse risk in offspring. Altered placental function driven by placental gene expression is a hypothesized mechanism underlying th
Externí odkaz:
https://doaj.org/article/9ac6b7096c2a406b87265d46e161cb52
Publikováno v:
Journal of Clinical Lipidology. 17:168-180
Blood lipids during pregnancy are associated with cardiovascular diseases and adverse pregnancy outcomes. Genome-wide association studies (GWAS) in predominantly male European ancestry populations have identified genetic loci associated with blood li
Autor:
Sifang Kathy Zhao, Edwina H Yeung, Marion Ouidir, Stefanie N Hinkle, Katherine L Grantz, Susanna D Mitro, Jing Wu, Danielle R Stevens, Suvo Chatterjee, Fasil Tekola-Ayele, Cuilin Zhang
Publikováno v:
Am J Clin Nutr
BACKGROUND: Physical activity (PA) prior to and during pregnancy may have intergenerational effects on offspring health through placental epigenetic modifications. We are unaware of epidemiologic studies on longitudinal PA and placental DNA methylati
Autor:
Himel Mallick, Suvo Chatterjee, Shrabanti Chowdhury, Saptarshi Chatterjee, Ali Rahnavard, Stephanie C. Hicks
Publikováno v:
Statistics in Medicine. 41:3492-3510
The performance of computational methods and software to identify differentially expressed features in single-cell RNA-sequencing (scRNA-seq) has been shown to be influenced by several factors, including the choice of the normalization method used an
Autor:
Suvo Chatterjee, Xuehuo Zeng, Marion Ouidir, Markos Tesfaye, Cuilin Zhang, Fasil Tekola-Ayele
Publikováno v:
Placenta
INTRODUCTION: Small for gestational age at birth (SGA), often a consequence of placental dysfunction, is a risk factor for neonatal morbidity and later life cardiometabolic diseases. There are sex differences in placental gene expression and fetal gr
Publikováno v:
Epigenomics
Aim: To investigate the association between placental genome-wide methylation at birth and antenatal depression and stress during pregnancy. Methods: We examined the association between placental genome-wide DNA methylation (n = 301) and maternal dep
Autor:
Himel Mallick, Suvo Chatterjee, Keith A. Crandall, Ali Rahnavard, Bahar Sayoldin, Fasil Tekola-Ayele
Publikováno v:
Bioinformatics
Motivation The discovery of biologically interpretable and clinically actionable communities in heterogeneous omics data is a necessary first step toward deriving mechanistic insights into complex biological phenomena. Here, we present a novel cluste