Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Suvi-Katriina Ruokonen"'
Autor:
Filip S. Ekholm, Suvi-Katriina Ruokonen, Marina Redón, Virve Pitkänen, Anja Vilkman, Juhani Saarinen, Jari Helin, Tero Satomaa, Susanne K. Wiedmer
Publikováno v:
Separations, Vol 6, Iss 1, p 1 (2018)
Antibody-drug conjugates (ADCs) are promising state-of-the-art biopharmaceutical drugs for selective drug-delivery applications and the treatment of diseases such as cancer. The idea behind the ADC technology is remarkable as it combines the highly s
Externí odkaz:
https://doaj.org/article/ce3bcce3ae8246aabae69be02a0c9af4
Autor:
Alexandra Robciuc, Corinna Sanwald, Susanne K. Wiedmer, Suvi-Katriina Ruokonen, Michael Lämmerhofer
Publikováno v:
Talanta. 197:472-481
This work presents the development and validation of a quantitative HILIC UHPLC-ESI-QTOF-MS/MS method for amino acids combined with untargeted metabolic profiling of human corneal epithelial (HCE) cells after treatment with ionic liquids. The work in
Publikováno v:
Langmuir
The aim of this study was to assess what properties of the pseudostationary phases in electrokinetic capillary chromatography affect the interactions between monomethyl auristatin E (MMAE) and hydrophilically modified structural analogues thereof wit
Autor:
Suvi-Katriina Ruokonen, Juha M. Holopainen, Susanne K. Wiedmer, Joanna Witos, Alexandra Robciuc, Antti H. Rantamäki, Pierre Jean Pisella
Publikováno v:
Cornea. 36:1249-1255
Purpose Most pure glaucoma drugs (pGDs) are hydrophobic substances intended to reduce elevated intraocular pressure. The aims of our study were to determine the toxicity of pGDs (brimonidine tartrate, brinzolamide, latanoprost, timolol maleate, and p
Autor:
Suvi-Katriina Ruokonen, Susanne K. Wiedmer, Patrik Ahvenainen, Kirsi Svedström, Inkeri Kontro, Filip Duša, Joanna Witos
Publikováno v:
Chemistry and Physics of Lipids. 201:59-66
The effects of ionic liquids on model phospholipid membranes were studied by small-angle X-ray scattering, dynamic light scattering (DLS) and zeta potential measurements. Multilamellar 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine liposomes and la
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Our study demonstrates that nanoplasmonic sensing (NPS) can be utilized for the determination of the phase transition temperature (Tm) of phospholipids. During the phase transition, the lipid bilayer undergoes a conformational change. Therefore, it i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb88a8306b7d9dd41e84b3a689d0442
https://aaltodoc.aalto.fi/handle/123456789/34485
https://aaltodoc.aalto.fi/handle/123456789/34485
Autor:
Tero Satomaa, Filip S. Ekholm, Marina Redón, Virve Pitkänen, Susanne K. Wiedmer, Juhani Saarinen, Jari Helin, Anja Vilkman, Suvi-Katriina Ruokonen
Publikováno v:
Separations, Vol 6, Iss 1, p 1 (2018)
Separations
Volume 6
Issue 1
Separations
Volume 6
Issue 1
Antibody-drug conjugates (ADCs) are promising state-of-the-art biopharmaceutical drugs for selective drug-delivery applications and the treatment of diseases such as cancer. The idea behind the ADC technology is remarkable as it combines the highly s
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 136:496-505
The worldwide use of ionic liquids (ILs) is steadily increasing, and even though they are often referred to as "green solvents" they have been reported to be toxic, especially toward aquatic organisms. In this work, we thoroughly study two phosphoniu
Autor:
Antti H. Rantamäki, Sami Hietala, Corinna Sanwald, Suvi-Katriina Ruokonen, Michael Lämmerhofer, Susanne K. Wiedmer, Joanna Witos, Alexandra Robciuc, Alistair W. T. King
Publikováno v:
Ruokonen, S K, Sanwald, C, Robciuc, A, Hietala, S, Rantamäki, A H, Witos, J, King, A W T, Lämmerhofer, M & Wiedmer, S K 2018, ' Correlation between Ionic Liquid Cytotoxicity and Liposome–Ionic Liquid Interactions ', Chemistry-A European Journal, vol. 24, no. 11, pp. 2669-2680 . https://doi.org/10.1002/chem.201704924
This study aims at extending the understanding of the toxicity mechanism of ionic liquids (ILs) using various analytical methods and cytotoxicity assays. The cytotoxicity of eight ILs and one zwitterionic compound was determined using mammalian and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac36dfafeacf5e3e4c5be0e390e047d
http://hdl.handle.net/10138/307532
http://hdl.handle.net/10138/307532
Autor:
Alistair W. T. King, Lasse Kyllönen, Antti H. Rantamäki, Susanne K. Wiedmer, Evangelos Sklavounos, Suvi-Katriina Ruokonen
Publikováno v:
Scientific Reports
Rantamäki, A H, Ruokonen, S K, Sklavounos, E, Kyllönen, L, King, A W T & Wiedmer, S K 2017, ' Impact of surface-active guanidinium-, tetramethylguanidinium-, and cholinium-based ionic liquids on vibrio Fischeri cells and dipalmitoylphosphatidylcholine liposomes ', Scientific Reports, vol. 7, 46673 . https://doi.org/10.1038/srep46673
Rantamäki, A H, Ruokonen, S K, Sklavounos, E, Kyllönen, L, King, A W T & Wiedmer, S K 2017, ' Impact of surface-active guanidinium-, tetramethylguanidinium-, and cholinium-based ionic liquids on vibrio Fischeri cells and dipalmitoylphosphatidylcholine liposomes ', Scientific Reports, vol. 7, 46673 . https://doi.org/10.1038/srep46673
We investigated the toxicological effect of seven novel cholinium, guanidinium, and tetramethylguanidinium carboxylate ionic liquids (ILs) from an ecotoxicological point of view. The emphasis was on the potential structure-toxicity dependency of thes