Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Suvi Silén"'
Autor:
Reija Randén-Brady, Timo Carpén, Laura C. Hautala, Tuomas Tolvanen, Caj Haglund, Sakari Joenväärä, Petri Mattila, Antti Mäkitie, Sanna Lehtonen, Jaana Hagström, Suvi Silén
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The increasing incidence of oropharyngeal squamous cell carcinoma (OPSCC) is primarily due to human papillomavirus, and understanding the tumor biology caused by the virus is crucial. Our goal was to investigate the proteins present in the s
Externí odkaz:
https://doaj.org/article/e6c8f9fd31ce44a6ac369bb73e9689a6
Autor:
Amy Dickinson, Sakari Joenväärä, Tiialotta Tohmola, Jutta Renkonen, Petri Mattila, Timo Carpén, Antti Mäkitie, Suvi Silén
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 1, Pp 26-39 (2024)
Abstract Protein glycosylation responds sensitively to disease states. It is implicated in every hallmark of cancer and has recently started to be considered as a hallmark itself. Changes in N‐glycosylation microheterogeneity are more dramatic than
Externí odkaz:
https://doaj.org/article/5535a1baeeaa44a4891f6896541cdc82
Autor:
Amy Dickinson, Mayank Saraswat, Sakari Joenväärä, Rahul Agarwal, Daniel Jyllikoski, Tommy Wilkman, Antti Mäkitie, Suvi Silén
Publikováno v:
Translational Oncology, Vol 13, Iss 10, Pp 100807- (2020)
Lipid metabolic reprogramming is one hallmark of cancer. Lipid metabolism is regulated by numerous enzymes, many of which are targeted by several drugs on the market. We aimed to characterize the lipid alterations in oral squamous cell carcinoma (OSC
Externí odkaz:
https://doaj.org/article/864f4a035f1b4ba09a82354a73f0d3c2
Autor:
Amy Dickinson, Mayank Saraswat, Stina Syrjänen, Tiialotta Tohmola, Robert Silén, Reija Randén-Brady, Timo Carpén, Jaana Hagström, Caj Haglund, Petri Mattila, Antti Mäkitie, Sakari Joenväärä, Suvi Silén
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233974 (2020)
BackgroundThe surrogate immunohistochemical marker, p16INK4a, is used in clinical practice to determine the high-risk human papillomavirus (HPV) status of oropharyngeal squamous cell carcinomas (OPSCC). With a specificity of 83%, this will misclassif
Externí odkaz:
https://doaj.org/article/3102e6c378c849ca9c6bfa6b280948e7
Autor:
Sanna-Maria Kivivuori, Ville Holmberg, Asko Järvinen, Hanna-Riikka Kreivi, Johanna Hästbacka, Atte Meretoja, Erik Forsblom, Elisa Kortela, Maarit J Ahava, Suvi Silén
Publikováno v:
Infectious Diseases. 53:789-799
Background Men reportedly suffer from a more severe disease and higher mortality during the global SARS-CoV-2 (Covid-19) pandemic. We analysed sex differences in a low epidemic area with low overall mortality in Covid-19 in a population based setting
Male sex predicts case-fatality in SARS-CoV-2 (COVID-19) – a phenomenon linked to systemic inflammation. We compared sex-related associations of inflammation parameters and outcome in a population-based setting with low case-fatality prior to wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2820e7cc0925c735fd079635c217adcf
Autor:
Salla Kattainen, Suvi Silén, Sanna-Maria Kivivuori, Erik Forsblom, J. Ollgren, Anu Kantele, Heli Salmi, Ville Holmberg, Atte Meretoja, Juulia Pynnönen, Johanna Hästbacka, Asko Järvinen
Publikováno v:
Clinical Microbiology and Infection
Funding Information: VH has received a grant from Finska L?kares?llskapet. AJ has received a grant from Wilhelm och Else Stockmanns stiftelse and speaker honoraria from Astellas, GlaxoSmithKline, Sanofi, Thermo Fisher, MSD, OrionPharma and UnimedicPh
Autor:
Jukka Ylikoski, Antti Mäkitie, Seppo Meri, Aaro Haapaniemi, Suvi Silén, Amy Dickinson, Hanna Kankaanpää
Publikováno v:
The Laryngoscope. 130
Objectives/Hypothesis We aimed to determine whether there was a difference between core and surface bacteriology of Finnish adults with recurrent or chronic tonsillitis to understand whether a surface swab is worthwhile and which bacteria are involve
Autor:
Suvi Silén, Omar Youssef, Alfio Ferlito, Antti Mäkitie, Markus Metsälä, Iain J. Nixon, Nabil F. Saba, Missak Haigentz, Alhadi Almangush, Vincent Vander Poorten, Juan P. Rodrigo
Publikováno v:
Mäkitie, A, Almangush, A, Youssef, O, Silen, S, Metsala, M, Nixon, I, Saba, N F & Ferlito, A 2019, ' Exhaled Breath Analysis in the Diagnosis of Head and Neck Cancer ', Head & neck . https://doi.org/10.1002/hed.26043
IntroductionHNCs constitute a heterogenous group of neoplasms. A recent report based on GLOBOCAN database estimated diagnosis of more than half million new cases of HNC during 2018 45, and the incidence is expected to continue increasing according to
Publikováno v:
Acta oto-laryngologica. 139(1)
Background: Laryngeal squamous cell carcinoma (LSCC) is rare in the young. Objectives: We characterized the clinical behavior of LSCC and assessed the presentation of second primary tumors (SPCs) in this patient population. Materials and methods: Dat