Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Suvi P, Kallio"'
Autor:
Janna Saarela, Suvi P Kallio, Daniel Chen, Alexandre Montpetit, Anne Jokiaho, Eva Choi, Rosanna Asselta, Denis Bronnikov, Matthew R Lincoln, A Dessa Sadovnick, Pentti J Tienari, Keijo Koivisto, Aarno Palotie, George C Ebers, Thomas J Hudson, Leena Peltonen
Publikováno v:
PLoS Genetics, Vol 2, Iss 3, p e42 (2006)
Multiple sclerosis (MS) is a chronic disease of the central nervous system responsible for a large portion of neurological disabilities in young adults. Similar to what occurs in numerous complex diseases, both unknown environmental factors and genet
Externí odkaz:
https://doaj.org/article/a69d4790ba4a44f8914d498c270be99d
Autor:
Teppo Varilo, Chris H. Polman, Maria-Liisa Sumelahti, Stacey Gabriel, Anna-Maija Kristiina Sulonen, Arpo Aromaa, David A. Hafler, Pentti J. Tienari, Inger-Lise Mero, Eveliina Jakkula, Stephen L. Hauser, Aarno Palotie, Daniel B. Mirel, Mauri Reunanen, Leena Peltonen, Ludwig Kappos, Shaun Purcell, Annette Bang Oturai, Anu Kemppinen, Helle Bach Søndergaard, Irina Elovaara, Hanne F. Harbo, Philip L. De Jager, Tuula Pirttilä, Keijo Koivisto, Virpi Leppa, Janna Saarela, Mark J. Daly, Suvi P. Kallio
Publikováno v:
American journal of human genetics, 86(2), 285-291. Cell Press
Jakkula, E, Leppa, V, Sulonen, A M, Varilo, T, Kallio, S, Kemppinen, A, Purcell, S, Koivisto, K, Tienari, P, Sumelahti, M L, Elovaara, I, Pirttila, T, Reunanen, M, Aromaa, A, Oturai, A B, Sondergaard, H B, Harbo, H F, Mero, I L, Gabriel, S B, Mirel, D B, Hauser, S L, Kappos, L, Polman, C H, de Jager, P L, Hafler, D A, Daly, M J, Palotie, A, Saarela, J & Peltonen, L 2010, ' Genome-wide Association Study in a High-Risk Isolate for Multiple Sclerosis Reveals Associated Variants in STAT3 Gene ', American journal of human genetics, vol. 86, no. 2, pp. 285-291 . https://doi.org/10.1016/j.ajhg.2010.01.017
Jakkula, E, Leppa, V, Sulonen, A M, Varilo, T, Kallio, S, Kemppinen, A, Purcell, S, Koivisto, K, Tienari, P, Sumelahti, M L, Elovaara, I, Pirttila, T, Reunanen, M, Aromaa, A, Oturai, A B, Sondergaard, H B, Harbo, H F, Mero, I L, Gabriel, S B, Mirel, D B, Hauser, S L, Kappos, L, Polman, C H, de Jager, P L, Hafler, D A, Daly, M J, Palotie, A, Saarela, J & Peltonen, L 2010, ' Genome-wide Association Study in a High-Risk Isolate for Multiple Sclerosis Reveals Associated Variants in STAT3 Gene ', American journal of human genetics, vol. 86, no. 2, pp. 285-291 . https://doi.org/10.1016/j.ajhg.2010.01.017
Genetic risk for multiple sclerosis (MS) is thought to involve both common and rare risk alleles. Recent GWAS and subsequent meta-analysis have established the critical role of the HLA locus and identified new common variants associated to MS. These
Autor:
Hanne F. Harbo, Leena Peltonen, Seppo Meri, Denis Bronnikov, Markku Viander, Irina Elovaara, Shaun Purcell, Philip L. De Jager, Åslaug R. Lorentzen, Aarno Palotie, Eveliina Jakkula, Minna Suvela, David A. Hafler, Jan Hillert, Pentti J. Tienari, Mauri Reunanen, Tuula Pirttilä, Frida Lundmark, Keijo Koivisto, Janna Saarela, Suvi P. Kallio, Mark J. Daly
Large case–control genome-wide association studies primarily expose common variants contributing to disease pathogenesis with modest effects. Thus, alternative strategies are needed to tackle rare, possibly more penetrant alleles. One strategy is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efea66f1f7c7ca72341d301b772f3f01
https://europepmc.org/articles/PMC2667286/
https://europepmc.org/articles/PMC2667286/
Autor:
Keijo Koivisto, Irina Elovaara, Anna-Maija Kristiina Sulonen, Pentti J. Tienari, Aarno Palotie, Leena Peltonen, Janna Saarela, Mauri Reunanen, Tuula Pirttilä, Minna Suvela, Pekka Ellonen, Suvi P. Kallio
Loss-of-function mutations of DAP12 and TREM2 cause a recessively inherited disease PLOSL, manifesting in brain white matter. The genes of the DAP12-TREM2 signaling receptor are located on 19q13.12 and 6p21.1, to which linkage has been observed also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169c276050971b5828635c5892c5be2e
https://europepmc.org/articles/PMC2682253/
https://europepmc.org/articles/PMC2682253/
Publikováno v:
Duodecim; laaketieteellinen aikakauskirja. 123(18)
Autor:
Janna Saarela, Denis Bronnikov, George C. Ebers, Thomas J. Hudson, Pentti J. Tienari, Keijo Koivisto, Matthew R. Lincoln, Anne Jokiaho, Alexandre Montpetit, Aarno Palotie, Suvi P. Kallio, A. Dessa Sadovnick, Rosanna Asselta, Leena Peltonen, Eva Choi, Daniel Chen
Publikováno v:
University of Helsinki
PLoS Genetics, Vol 2, Iss 3, p e42 (2006)
PLoS Genetics
PLoS Genetics, Vol 2, Iss 3, p e42 (2006)
PLoS Genetics
Multiple sclerosis (MS) is a chronic disease of the central nervous system responsible for a large portion of neurological disabilities in young adults. Similar to what occurs in numerous complex diseases, both unknown environmental factors and genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9faad23fd8d6a451e7ea14c5f30d36
https://researchportal.helsinki.fi/en/publications/7bdfa096-ffd5-40bc-b59b-448e7aae553f
https://researchportal.helsinki.fi/en/publications/7bdfa096-ffd5-40bc-b59b-448e7aae553f