Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Suvi M. Kuosmanen"'
Publikováno v:
Redox Biology, Vol 18, Iss , Pp 77-83 (2018)
Oxidative stress predisposes to several aging-associated diseases, such as cardiovascular diseases and cancer. In aging, increase in the production of reactive oxygen species is typically accompanied with a decline in adaptive stress responses to oxi
Externí odkaz:
https://doaj.org/article/14ee52fdebf1425f9979c07fdf694ff5
Publikováno v:
Redox Biology, Vol 1, Iss 1, Pp 45-49 (2013)
The Keap1-Nrf2 pathway is the major regulator of cytoprotective responses to oxidative and electrophilic stress. Although cell signaling pathways triggered by the transcription factor Nrf2 prevent cancer initiation and progression in normal and prema
Externí odkaz:
https://doaj.org/article/70d22406e453436b8fe9ea4a4adc6c3a
Autor:
Anna-Liisa Levonen, Seppo Ylä-Herttuala, Minna U. Kaikkonen, Hanna P. Lesch, Haritha Samaranayake, Jari P. Lappalainen, Jere T. Pikkarainen, Emilia Kansanen, Suvi M. Kuosmanen, Heidi M. Laitinen, Ann-Marie Määttä, Anna-Kaisa Ruotsalainen, Hanna M. Leinonen
Nuclear factor erythroid-2 related factor 2 (Nrf2) is a transcription factor that regulates protection against a wide variety of toxic insults to cells, including cytotoxic cancer chemotherapeutic drugs. Many lung cancer cells harbor a mutation in ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90bf3aae97f86781220c782bc7ad87cf
https://doi.org/10.1158/0008-5472.c.6503937.v1
https://doi.org/10.1158/0008-5472.c.6503937.v1
Autor:
Anna-Liisa Levonen, Seppo Ylä-Herttuala, Minna U. Kaikkonen, Hanna P. Lesch, Haritha Samaranayake, Jari P. Lappalainen, Jere T. Pikkarainen, Emilia Kansanen, Suvi M. Kuosmanen, Heidi M. Laitinen, Ann-Marie Määttä, Anna-Kaisa Ruotsalainen, Hanna M. Leinonen
PDF file - 57K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8be17f97492eeb4676915474595fc4
https://doi.org/10.1158/0008-5472.22394055.v1
https://doi.org/10.1158/0008-5472.22394055.v1
Autor:
Anna-Liisa Levonen, Seppo Ylä-Herttuala, Minna U. Kaikkonen, Hanna P. Lesch, Haritha Samaranayake, Jari P. Lappalainen, Jere T. Pikkarainen, Emilia Kansanen, Suvi M. Kuosmanen, Heidi M. Laitinen, Ann-Marie Määttä, Anna-Kaisa Ruotsalainen, Hanna M. Leinonen
PDF file - 324K, The effect of ganciclovir and doxorubicin on ARE activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551fa5c0ca79e2e61797c8aabe5105b3
https://doi.org/10.1158/0008-5472.22394058.v1
https://doi.org/10.1158/0008-5472.22394058.v1
Publikováno v:
Redox Biology, Vol 18, Iss, Pp 77-83 (2018)
Redox Biology
Redox Biology
Oxidative stress predisposes to several aging-associated diseases, such as cardiovascular diseases and cancer. In aging, increase in the production of reactive oxygen species is typically accompanied with a decline in adaptive stress responses to oxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc6e03ee3952ce2e8e1714852e516412
http://www.sciencedirect.com/science/article/pii/S2213231718303902
http://www.sciencedirect.com/science/article/pii/S2213231718303902
Autor:
Ashish Jain, Petri Pölönen, Arto Mannermaa, Ashik Jawahar Deen, Anna-Liisa Levonen, Jaana M. Hartikainen, Pasi Tavi, Terje Johansen, Suvi M. Kuosmanen, Mimmi Mononen, Matti Nykter, Henna-Kaisa Jyrkkänen, Tomi Tuomainen, Merja Heinäniemi, Sanna Pasonen-Seppänen, Hanna Leinonen
Accumulating evidence suggests that constitutively active Nrf2 has a pivotal role in cancer as it induces pro-survival genes that promote cancer cell proliferation and chemoresistance. The mechanisms of Nrf2 dysregulation and functions in cancer have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94f6e648959614be896b3523fd2f2c7
https://hdl.handle.net/10037/17781
https://hdl.handle.net/10037/17781
Autor:
Heidi Hynynen, Anna-Liisa Levonen, Suvi M. Kuosmanen, Emilia Kansanen, Anna-Kaisa Ruotsalainen
Publikováno v:
Molecular pharmacology. 92(4)
Nitro-fatty acids are reactive signaling mediators that are formed when unsaturated fatty acids react with nitric oxide or nitric oxide-derived species. Nitro-fatty acids can modify specific signaling pathways via post-translational modifications of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1fa632382d7459365866246cfec73f
https://pubmed.ncbi.nlm.nih.gov/28778983
https://pubmed.ncbi.nlm.nih.gov/28778983
Autor:
Pauli Tuoresmäki, Suvi M. Kuosmanen, Mikko Hippeläinen, Kati Pulkkinen, Anna-Liisa Levonen, Juha Hartikainen, Pasi Tavi, Virve Sihvola, Henna-Kaisa Jyrkkänen, Sami Heikkinen, Hannu Kokki, Minna U. Kaikkonen, Emilia Kansanen
Publikováno v:
Nucleic Acids Research
Phospholipids, such as 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (PAPC), are the major components of cell membranes. Their exposure to reactive oxygen species creates oxidized phospholipids, which predispose to the development of chronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c679a75917f145227a407e907e9338c
https://erepo.uef.fi/handle/123456789/5749
https://erepo.uef.fi/handle/123456789/5749
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
Endothelial plasticity enables the cells to switch their phenotype according to the surrounding vascular microenvironment. MicroRNAs (miRNAs) are small noncoding RNAs that control endothelial plasticity. The objective of this study was to investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410be3078339ac4fff91ae2c82f1b790
https://erepo.uef.fi/handle/123456789/5175
https://erepo.uef.fi/handle/123456789/5175