Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Suvi Heinimäki"'
Autor:
Isabel Leroux-Roels, Cathy Maes, Jasper Joye, Bart Jacobs, Franziska Jarczowski, André Diessner, Yorick Janssens, Gwenn Waerlop, Kirsi Tamminen, Suvi Heinimäki, Vesna Blazevic, Geert Leroux-Roels, Victor Klimyuk, Hiroshi Adachi, Kazuyuki Hiruta, Frank Thieme
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Noroviruses (NoV) are the leading cause of epidemic acute gastroenteritis in humans worldwide and a safe and effective vaccine is needed. Here, a phase I, double-blind, placebo-controlled clinical trial was performed in 60 healthy adults, 18 to 40 ye
Externí odkaz:
https://doaj.org/article/bb6df2d5e1e744729c3ccc75dafbda24
Autor:
Vili Lampinen, Suvi Heinimäki, Olli H. Laitinen, Marko Pesu, Minna M. Hankaniemi, Vesna Blazevic, Vesa P. Hytönen
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Virus-like particle (VLP) vaccines have recently emerged as a safe and effective alternative to conventional vaccine technologies. The strong immunogenic effects of VLPs can be harnessed for making vaccines against any pathogen by
Externí odkaz:
https://doaj.org/article/ffa2db15f11a40eca0c3dce791cdb813
Publikováno v:
Journal of Immunology Research, Vol 2020 (2020)
We have previously shown that rotavirus (RV) inner capsid protein VP6 has an adjuvant effect on norovirus (NoV) virus-like particle- (VLP-) induced immune responses and studied the adjuvant mechanism in immortalized cell lines used as antigen-present
Externí odkaz:
https://doaj.org/article/56de68a6fab74eb6b38589c3a759f586
Publikováno v:
Vaccines, Vol 9, Iss 7, p 733 (2021)
Vaccines based on mRNA and viral vectors are currently used in the frontline to combat the ongoing pandemic caused by the novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). However, there is still an urgent need for alternative vacci
Externí odkaz:
https://doaj.org/article/e3b59fa5129f4ca69725b475c5ac25dd
Publikováno v:
Vaccines, Vol 8, Iss 3, p 365 (2020)
Novel adjuvants present a concern for adverse effects, generating a need for alternatives. Rotavirus inner capsid VP6 protein could be considered a potential candidate, due to its ability to self-assemble into highly immunogenic nanospheres and nanot
Externí odkaz:
https://doaj.org/article/c80a5462ef0e4bab93b087dc49dbcc9e
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
Norovirus (NoV) is a main cause of acute gastroenteritis across all ages worldwide. NoV vaccine candidates currently in clinical trials are based on noninfectious highly immunogenic virus-like particles (VLPs) delivered intramuscularly (IM). Since No
Externí odkaz:
https://doaj.org/article/817f2c612ed1437bac71020de68f08d0
Publikováno v:
Archives of Virology
Recombinant protein technology enables the engineering of modern vaccines composed of a carrier protein displaying poorly immunogenic heterologous antigens. One promising carrier is based on the rotavirus inner-capsid VP6 protein. We explored differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d4931c0ce5c337bef051ecff6a5a46
http://europepmc.org/articles/PMC7567002
http://europepmc.org/articles/PMC7567002
Autor:
Suvi Heinimäki, Vili Lampinen, Kirsi Tamminen, Minna M. Hankaniemi, Maria Malm, Vesa P. Hytönen, Vesna Blazevic
Virus-like particles (VLPs) modified through different molecular technologies are employed as delivery vehicles or platforms for heterologous antigen display. We have recently created a norovirus (NoV) VLP platform, where two influenza antigens, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8d28b4d1b1be7d4f8752fe639dc18a
https://trepo.tuni.fi/handle/10024/136414
https://trepo.tuni.fi/handle/10024/136414
Publikováno v:
Vaccines, Vol 9, Iss 733, p 733 (2021)
Vaccines
Vaccines
Vaccines based on mRNA and viral vectors are currently used in the frontline to combat the ongoing pandemic caused by the novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). However, there is still an urgent need for alternative vacci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44dbb94d432acc1caa8ac5018dbd60a8
https://www.mdpi.com/2076-393X/9/7/733
https://www.mdpi.com/2076-393X/9/7/733
Publikováno v:
Vaccines
Vaccines, Vol 8, Iss 365, p 365 (2020)
Volume 8
Issue 3
Vaccines, Vol 8, Iss 365, p 365 (2020)
Volume 8
Issue 3
Novel adjuvants present a concern for adverse effects, generating a need for alternatives. Rotavirus inner capsid VP6 protein could be considered a potential candidate, due to its ability to self-assemble into highly immunogenic nanospheres and nanot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eadc91e21c0a90b17e8b4c4e2dd1eb9c
http://europepmc.org/articles/PMC7565724
http://europepmc.org/articles/PMC7565724