Two codependent routes lead to high-level MRSA.

Autor: Adedeji-Olulana AF; School of Mathematical and Physical Sciences, University of Sheffield, Sheffield, UK., Wacnik K; School of Biosciences, University of Sheffield, Sheffield, UK.; The Florey Institute, University of Sheffield, Sheffield, UK., Lafage L; School of Biosciences, University of Sheffield, Sheffield, UK.; The Florey Institute, University of Sheffield, Sheffield, UK., Pasquina-Lemonche L; School of Mathematical and Physical Sciences, University of Sheffield, Sheffield, UK.; The Florey Institute, University of Sheffield, Sheffield, UK., Tinajero-Trejo M; School of Biosciences, University of Sheffield, Sheffield, UK.; The Florey Institute, University of Sheffield, Sheffield, UK., Sutton JAF; School of Biosciences, University of Sheffield, Sheffield, UK.; The Florey Institute, University of Sheffield, Sheffield, UK., Bilyk B; School of Biosciences, University of Sheffield, Sheffield, UK.; The Florey Institute, University of Sheffield, Sheffield, UK., Irving SE; School of Biosciences, University of Sheffield, Sheffield, UK.; The Florey Institute, University of Sheffield, Sheffield, UK., Portman Ross CJ; School of Biosciences, University of Sheffield, Sheffield, UK.; The Florey Institute, University of Sheffield, Sheffield, UK., Meacock OJ; School of Mathematical and Physical Sciences, University of Sheffield, Sheffield, UK., Randerson SA; School of Mathematical and Physical Sciences, University of Sheffield, Sheffield, UK., Beattie E; School of Mathematical and Physical Sciences, University of Sheffield, Sheffield, UK., Owen DS; School of Biosciences, University of Sheffield, Sheffield, UK., Florence J; School of Biosciences, University of Sheffield, Sheffield, UK.; The Florey Institute, University of Sheffield, Sheffield, UK., Durham WM; School of Mathematical and Physical Sciences, University of Sheffield, Sheffield, UK., Hornby DP; School of Biosciences, University of Sheffield, Sheffield, UK.; The Florey Institute, University of Sheffield, Sheffield, UK., Corrigan RM; School of Biosciences, University of Sheffield, Sheffield, UK.; The Florey Institute, University of Sheffield, Sheffield, UK.; School of Medicine, University College Dublin, Dublin, Ireland., Green J; School of Biosciences, University of Sheffield, Sheffield, UK.; The Florey Institute, University of Sheffield, Sheffield, UK., Hobbs JK; School of Mathematical and Physical Sciences, University of Sheffield, Sheffield, UK., Foster SJ; School of Biosciences, University of Sheffield, Sheffield, UK.; The Florey Institute, University of Sheffield, Sheffield, UK.

Publikováno v: Science (New York, N.Y.) [Science] 2024 Nov; Vol. 386 (6721), pp. 573-580. Date of Electronic Publication: 2024 Oct 31.

Clonal population expansion of Staphylococcus aureus occurs due to escape from a finite number of intraphagocyte niches.

Autor: Pidwill GR; School of Biosciences, University of Sheffield, Sheffield, S10 2TN, UK.; Florey Institute, University of Sheffield, Sheffield, S10 2TN, UK., Pyrah JF; School of Biosciences, University of Sheffield, Sheffield, S10 2TN, UK.; Florey Institute, University of Sheffield, Sheffield, S10 2TN, UK.; The Bateson Centre, University of Sheffield, Sheffield, S10 2TN, UK., Sutton JAF; School of Biosciences, University of Sheffield, Sheffield, S10 2TN, UK.; Florey Institute, University of Sheffield, Sheffield, S10 2TN, UK., Best A; School of Mathematics & Statistics, University of Sheffield, Sheffield, S3 7RH, UK. a.best@sheffield.ac.uk., Renshaw SA; Florey Institute, University of Sheffield, Sheffield, S10 2TN, UK. s.a.renshaw@sheffield.ac.uk.; The Bateson Centre, University of Sheffield, Sheffield, S10 2TN, UK. s.a.renshaw@sheffield.ac.uk.; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, S10 2RX, UK. s.a.renshaw@sheffield.ac.uk., Foster SJ; School of Biosciences, University of Sheffield, Sheffield, S10 2TN, UK. s.foster@sheffield.ac.uk.; Florey Institute, University of Sheffield, Sheffield, S10 2TN, UK. s.foster@sheffield.ac.uk.

Publikováno v: Scientific reports [Sci Rep] 2023 Jan 21; Vol. 13 (1), pp. 1188. Date of Electronic Publication: 2023 Jan 21.

Coupling Novel Probes with Molecular Localization Microscopy Reveals Cell Wall Homeostatic Mechanisms in Staphylococcus aureus .

Autor: Lund VA; School of Biosciences, University of Sheffield, Sheffield S10 2TN, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield S10 2TN, United Kingdom., Gangotra H; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield S10 2TN, United Kingdom.; The Department of Chemistry, University of Sheffield, Sheffield S3 7HF, United Kingdom., Zhao Z; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield S10 2TN, United Kingdom.; The Department of Chemistry, University of Sheffield, Sheffield S3 7HF, United Kingdom., Sutton JAF; School of Biosciences, University of Sheffield, Sheffield S10 2TN, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield S10 2TN, United Kingdom., Wacnik K; School of Biosciences, University of Sheffield, Sheffield S10 2TN, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield S10 2TN, United Kingdom., DeMeester K; Department of Chemistry and Biochemistry and Department of Biological Sciences, University of Delaware, Newark, Delaware 19716, United States., Liang H; Department of Chemistry and Biochemistry and Department of Biological Sciences, University of Delaware, Newark, Delaware 19716, United States., Santiago C; Department of Chemistry and Biochemistry and Department of Biological Sciences, University of Delaware, Newark, Delaware 19716, United States., Leimkuhler Grimes C; Department of Chemistry and Biochemistry and Department of Biological Sciences, University of Delaware, Newark, Delaware 19716, United States., Jones S; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield S10 2TN, United Kingdom.; The Department of Chemistry, University of Sheffield, Sheffield S3 7HF, United Kingdom., Foster SJ; School of Biosciences, University of Sheffield, Sheffield S10 2TN, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield S10 2TN, United Kingdom.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2022 Dec 16; Vol. 17 (12), pp. 3298-3305. Date of Electronic Publication: 2022 Nov 22.

Staphylococcus aureus cell wall structure and dynamics during host-pathogen interaction.

Autor: Sutton JAF; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom., Carnell OT; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom., Lafage L; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom., Gray J; Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Biboy J; Centre for Bacterial Cell Biology, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Gibson JF; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom.; The Bateson Centre, University of Sheffield, Firth Court, Western Bank, Sheffield, United Kingdom., Pollitt EJG; Department of Biomedical Science, University of Sheffield, Firth Court, Western Bank, Sheffield, United Kingdom., Tazoll SC; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom., Turnbull W; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom., Hajdamowicz NH; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom.; Department of Infection, Immunity and Cardiovascular Diseases, University of Sheffield, Beech Hill Road, Sheffield United Kingdom., Salamaga B; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom., Pidwill GR; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom., Condliffe AM; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom.; Department of Infection, Immunity and Cardiovascular Diseases, University of Sheffield, Beech Hill Road, Sheffield United Kingdom., Renshaw SA; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom.; The Bateson Centre, University of Sheffield, Firth Court, Western Bank, Sheffield, United Kingdom.; Department of Infection, Immunity and Cardiovascular Diseases, University of Sheffield, Beech Hill Road, Sheffield United Kingdom., Vollmer W; Centre for Bacterial Cell Biology, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Foster SJ; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom.

Publikováno v: PLoS pathogens [PLoS Pathog] 2021 Mar 31; Vol. 17 (3), pp. e1009468. Date of Electronic Publication: 2021 Mar 31 (Print Publication: 2021).