Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Suthira, Owlarn"'
Autor:
Suthira Owlarn, Felix Klenner, David Schmidt, Franziska Rabert, Antonio Tomasso, Hanna Reuter, Medhanie A. Mulaw, Sören Moritz, Luca Gentile, Gilbert Weidinger, Kerstin Bartscherer
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Some wounds trigger regeneration, while others simply heal but how this is regulated is unclear. Here, by manipulating ERK and Wnt signalling pathways, the authors create headless planarians and finless zebrafish and show that wounds that normally on
Externí odkaz:
https://doaj.org/article/e4121786dfd84d7e91076c345878d239
Autor:
Hanna Reuter, Martin März, Matthias C. Vogg, David Eccles, Laura Grífol-Boldú, Daniel Wehner, Suthira Owlarn, Teresa Adell, Gilbert Weidinger, Kerstin Bartscherer
Publikováno v:
Cell Reports, Vol 10, Iss 2, Pp 253-265 (2015)
Wnt/β-catenin signaling regulates tissue homeostasis and regeneration in metazoans. In planarians—flatworms with high regenerative potential—Wnt ligands are thought to control tissue polarity by shaping a β-catenin activity gradient along the a
Externí odkaz:
https://doaj.org/article/7ee3519e493d4fb8a16e1158fc5daa07
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27927 (2011)
The current model of planarian anterior regeneration evokes the establishment of low levels of Wnt signalling at anterior wounds, promoting anterior polarity and subsequent elaboration of anterior fate through the action of the TALE class homeodomain
Externí odkaz:
https://doaj.org/article/ef8c2c82fd7d492da0a7cecef43276ae
Autor:
Kerstin Bartscherer, Suthira Owlarn, Antonio Tomasso, Luca Gentile, Gilbert Weidinger, David Schmidt, Felix Klenner, Franziska Rabert, Medhanie A. Mulaw, Soeren Moritz, Hanna Reuter
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications
Nature Communications
Despite the identification of numerous regulators of regeneration in different animal models, a fundamental question remains: why do some wounds trigger the full regeneration of lost body parts, whereas others resolve by mere healing? By selectively
Autor:
Wei Wu, Yuvia A. Pérez Rico, Jianlei Xie, Kerstin Bartscherer, Luca Gentile, Suthira Owlarn, Yoko Suzuki, Matthias C. Vogg
Publikováno v:
Developmental Biology. 390(2):136-148
Planarians can regenerate their head within days. This process depends on the direction of adult stem cells to wound sites and the orchestration of their progenitors to commit to appropriate lineages and to arrange into patterned tissues. We identifi
Publikováno v:
Genome Biology
Background Planarian flatworms can regenerate their head, including a functional brain, within less than a week. Despite the enormous potential of these animals for medical research and regenerative medicine, the mechanisms of regeneration and the mo
Autor:
Kerstin Bartscherer, Daniel Wehner, Gilbert Weidinger, David Eccles, Martin März, Teresa Adell, Matthias Christian Vogg, Suthira Owlarn, Laura Grífol-Boldú, Hanna Reuter
Publikováno v:
Cell Reports, Vol 10, Iss 2, Pp 253-265 (2015)
SummaryWnt/β-catenin signaling regulates tissue homeostasis and regeneration in metazoans. In planarians—flatworms with high regenerative potential—Wnt ligands are thought to control tissue polarity by shaping a β-catenin activity gradient alon