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pro vyhledávání: '"Suter, David Michael"'
Autor:
Alber, Andrea Brigitta, Paquet, Eric Raphael, Biserni, Martina, Naef, Felix, Suter, David Michael
Publikováno v:
In Molecular Cell 20 September 2018 71(6):1079-1091
Publikováno v:
In Molecular Cell 26 October 2012 48(2):277-287
Akademický článek
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Akademický článek
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Autor:
Alber, Andrea Brigitta, Paquet, Eric Raphael, Biserni, Martina, Naef, Felix, Suter, David Michael
Cells need to reliably control their proteome composition to maintain homeostasis and regulate growth. How protein synthesis and degradation interplay to control protein expression levels remains unclear. Here, we combined a tandem fluorescent timer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______185::b8d56cad0ad9385c7ae03a88ae90d588
https://infoscience.epfl.ch/record/261535
https://infoscience.epfl.ch/record/261535
Protein expression levels depend on the balance between their synthesis and degradation rates. Even quiescent (G(0)) cells display a continuous turnover of proteins, despite protein levels remaining largely constant over time. In cycling cells, globa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______185::e9d2340350768a34dfe9407c8a098080
https://infoscience.epfl.ch/record/265371
https://infoscience.epfl.ch/record/265371
Autor:
Mandic, Aleksandra
Quantitative studies of gene expression in have shown widespread variability in transcript and protein product abundance at the single-cell level. Such fluctuations in gene expression have been shown to lead to heterogeneous cellular responses and ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0603c9bbd70723895f84c37cec1da61
Autor:
Strebinger, Daniel
Embryonic stem (ES) cells have the capacity to give rise to all cell types of the adult organism and can be used as a model to study early cell fate decisions as they closely recapitulate in vivo events. The M and G1 phases have been suggested to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565b9ea7e16d3b250f3a9fbd034ad050
Autor:
Nicolas, Damien Lionel
Isogenic cells sharing a common environment present a large degree of heterogeneity in gene expression, and stochasticity inherent to transcription substantially participates in this cell-to-cell variability. Notably, a majority of mammalian genes ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1949cd2c38ee322abed0030205cca660
Mitochondrial diseases are rare and severe conditions with debilitating symptoms. Biochemical defects in mitochondria however are common. The difference between these two frequencies is suspected to lie in the capability of the cells to adapt to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc875d9fb4fc0e8fd85dd3ebd555f00e
https://infoscience.epfl.ch/record/291917
https://infoscience.epfl.ch/record/291917