Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sutapa Kole"'
Publikováno v:
BioTechniques, Vol 52, Iss 4, Pp 1-7 (2012)
Members of the heat shock protein-90 (Hsp90) family are key regulators of biological processes through dynamic interaction with a multitude of protein partners. However, the transient nature of these interactions hinders the identification of Hsp90 i
Externí odkaz:
https://doaj.org/article/46e21847c704438aa3b62ca130150581
Autor:
Sutapa Kole, Jennifer L. Fiori, Tie Nian Zhu, Michel Bernier, Ashani T. Weeraratna, Christa Morris, Fred E. Indig, Brittany P. Frank, George Elias, Michael P. O'Connell, Joanne H. Hasskamp, Keith S. Hoek
Publikováno v:
Endocrinology. 150:2551-2560
The actin-binding protein filamin A (FLNa) affects the intracellular trafficking of various classes of receptors and has a potential role in oncogenesis. However, it is unclear whether FLNa regulates the signaling capacity and/or down-regulation of t
Publikováno v:
Endocrinology. 150:1122-1131
S-glutathionylation is a physiological, reversible protein modification of cysteine residues with glutathione in response to mild oxidative stress. Because the key cell growth regulator signal transducer and activator of transcription (STAT) 3 is par
Autor:
Michel Bernier, Sanjay K. Pandey, Tienian Zhu, Rui-Jing Zhao, Hua-Jun He, Alexandre Maciuk, Sutapa Kole, Rafael deCabo, Yong-Kook Kwon
Publikováno v:
Journal of Biological Chemistry. 281:2551-2561
IκB kinase (IKK) catalytic subunits play a key role in cytokinemediated nuclear factor (NF)-κB signaling, and a loss of NF-κB function appears to inhibit inflammation and oncogenesis. Manumycin A is a potent and selective farnesyltransferase inhib
Publikováno v:
Biochemistry. 39:12513-12521
CHO cells expressing the human insulin receptors (IR) were used to evaluate the effect of the potent farnesyltransferase inhibitor, manumycin, on insulin antiapoptotic function. Cell treatment with manumycin blocked insulin's ability to suppress pro-
Autor:
Pavel V. Avdonin, Michael J. Garant, Sutapa Kole, Chahrzad Montrose-Rafizadeh, Michel Bernier, Buel D. Rodgers, Michael A. Levine, William F. Schwindinger, Huan Yang
Publikováno v:
Scopus-Elsevier
Chinese hamster ovary (CHO) cells stably expressing the human insulin receptor and the rat glucagon-like peptide-1 (GLP-1) receptor (CHO/GLPR) were used to study the functional coupling of the GLP-1 receptor with G proteins and to examine the regulat
Publikováno v:
Biochemistry. 37:15747-15757
We have sought to determine whether insulin can promote cell survival and protect Chinese hamster ovary (CHO) cells from apoptosis induced by serum starvation. Low concentrations of insulin were antiapoptotic for cells overexpressing wild-type insuli
Autor:
Michel Bernier, Hemanta K. Kole, Anthony S. Liotta, Jesse Roth, Chahrzad Montrose-Rafizadeh, Sutapa Kole
Publikováno v:
Journal of Biological Chemistry. 271:31619-31626
The role of the insulin receptor COOH-terminal domain in the regulation of insulin signal transduction was explored with a variety of synthetic peptides. One of the peptides, termed peptide HC, whose structure corresponds to residues 1293-1307 of the
Adaptive responses to physical and inflammatory stressors are mediated by transcription factors and molecular chaperones. The transcription factor heat shock factor 1 (HSF1) has been implicated in extending lifespan in part by increasing expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72aa15c088e8f0f4cdfe8196619acf15
https://europepmc.org/articles/PMC2950225/
https://europepmc.org/articles/PMC2950225/