Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Susumu Ueno"'
Publikováno v:
Materials, Vol 16, Iss 15, p 5230 (2023)
Sodium monofluorophosphate (Na2FPO3, MFP) is mainly used as an ingredient in fluoride-based dentifrices as it has a high safety profile, with one-third of the toxicity of sodium fluoride (NaF), as well as the ability to reach deep into the dentin. Th
Externí odkaz:
https://doaj.org/article/eb0132e2305a4488b759b394fa2930cb
Autor:
Takafumi Horishita, Yuichi Ogata, Reiko Horishita, Ryo Fukui, Kuniaki Moriwaki, Susumu Ueno, Nobuyuki Yanagihara, Yasuhito Uezono, Yuka Sudo, Kouichiro Minami
Publikováno v:
Journal of Pharmacological Sciences, Vol 142, Iss 4, Pp 140-147 (2020)
Carvacrol is the predominant monoterpene in essential oils from many aromatic plants. Several animal studies showing analgesic effects of carvacrol indicate potential of carvacrol as a new medication for patients with refractory pain. Voltage-gated s
Externí odkaz:
https://doaj.org/article/490bd51b04164ad497dfc78207fd2865
Autor:
Takafumi Horishita, Nobuyuki Yanagihara, Susumu Ueno, Dan Okura, Reiko Horishita, Tomoko Minami, Yuichi Ogata, Yuka Sudo, Yasuhito Uezono, Takashi Kawasaki
Publikováno v:
Journal of Pharmacological Sciences, Vol 137, Iss 1, Pp 93-97 (2018)
The neurosteroid allopregnanolone has potent analgesic effects, and its potential use for neuropathic pain is supported by recent reports. However, the analgesic mechanisms are obscure. The voltage-gated sodium channels (Nav) α subunit Nav1.3 is tho
Externí odkaz:
https://doaj.org/article/10d466bced6e43b88f420d6a937a3725
Autor:
Nobuyuki Yanagihara, Han Zhang, Yumiko Toyohira, Keita Takahashi, Susumu Ueno, Masato Tsutsui, Kojiro Takahashi
Publikováno v:
Journal of Pharmacological Sciences, Vol 124, Iss 2, Pp 123-128 (2014)
Flavonoids are biologically active polyphenolic compounds widely distributed in plants. Recent research has focused on high dietary intake of flavonoids because of their potential to reduce the risks of diseases such as cardiovascular diseases, diabe
Externí odkaz:
https://doaj.org/article/13429865ba4348648ce2405a0ea0b6e9
Autor:
Hirohide Inagaki, Yumiko Toyohira, Keita Takahashi, Susumu Ueno, Go Obara, Toshinori Kawagoe, Masato Tsutsui, Toru Hachisuga, Nobuyuki Yanagihara
Publikováno v:
Journal of Pharmacological Sciences, Vol 124, Iss 1, Pp 66-75 (2014)
Abstract.: We previously reported the occurrence and function of plasma membrane estrogen receptors in cultured bovine adrenal medullary cells. Here we report the effects of raloxifene and tamoxifen, selective estrogen receptor modulators, on plasma
Externí odkaz:
https://doaj.org/article/b603c4c15a304a1983129250dd2ef659
Autor:
Go Obara, Yumiko Toyohira, Hirohide Inagaki, Keita Takahashi, Takafumi Horishita, Takashi Kawasaki, Susumu Ueno, Masato Tsutsui, Takeyoshi Sata, Nobuyuki Yanagihara
Publikováno v:
Journal of Pharmacological Sciences, Vol 121, Iss 2, Pp 138-147 (2013)
(±)-Pentazocine (PTZ), a non-narcotic analgesic, is used for the clinical management of moderate to severe pain. To study the effect of PTZ on the descending noradrenergic inhibitory system, in the present study we examined the effect of [3H]norepin
Externí odkaz:
https://doaj.org/article/de4da72bef9b4deeb0c4e7a436537c4e
Autor:
Takafumi Horishita, Susumu Ueno, Nobuyuki Yanagihara, Yuka Sudo, Yasuhito Uezono, Dan Okura, Takeyoshi Sata
Publikováno v:
Journal of Pharmacological Sciences, Vol 120, Iss 1, Pp 54-58 (2012)
Neurosteroids are known as allosteric modulators of the ligand-gated ion channel superfamily. Voltage-gated sodium channels (Nav) play an important role in mediating excitotoxic damages. Here we report the effects of neurosteroids on the function of
Externí odkaz:
https://doaj.org/article/dd256dd4d40f4de9bf27cc1b7230afde
Autor:
Naoya Morisada, Masayoshi Nomura, Hisae Nishii, Yumi Furuno, Mayuko Sakanashi, Ken Sabanai, Yumiko Toyohira, Susumu Ueno, Seiji Watanabe, Masahito Tamura, Tetsuro Matsumoto, Akihide Tanimoto, Yasuyuki Sasaguri, Hiroaki Shimokawa, Koichi Kusuhara, Nobuyuki Yanagihara, Akira Shirahata, Masato Tsutsui
Publikováno v:
Journal of Pharmacological Sciences, Vol 114, Iss 4, Pp 379-389 (2010)
Abstract.: The role of nitric oxide (NO) derived from all three NO synthases (NOSs) in renal lesion formation remains to be fully elucidated. We addressed this point in mice lacking all NOSs. Renal injury was induced by unilateral ureteral obstructio
Externí odkaz:
https://doaj.org/article/ce00b35f732f45f1b7369366aef7d29a
Direct Inhibition of N-Methyl-D-Aspartate (NMDA)-Receptor Function by Antiglaucomatous β-Antagonists
Autor:
Tatsuo Nagata, Susumu Ueno, Hirofumi Morita, Toshiaki Kubota, Yumiko Toyohira, Masato Tsutsui, Akihiko Tawara, Nobuyuki Yanagihara
Publikováno v:
Journal of Pharmacological Sciences, Vol 106, Iss 3, Pp 423-434 (2008)
In the present study, we investigated the direct effects of antiglaucoma drugs (timolol, betaxolol, pilocarpine, and latanoprost) on N-methyl-D-aspartate (NMDA)-receptor function using a Xenopus oocytes expression system and electrophysiological tech
Externí odkaz:
https://doaj.org/article/8b1cc9dffda24632a5921fc6e8381292
Autor:
Mayumi Tsuji, Chihaya Koriyama, Yasuhiro Ishihara, Toyohi Isse, Tsunetoshi Ishizuka, Wataru Hasegawa, Motohide Goto, Rie Tanaka, Noriaki Kakiuchi, Hajime Hori, Kazuhiro Yatera, Naoki Kunugita, Megumi Yamamoto, Toshihide Sakuragi, Yoshiko Yasumura, Maori Kono, Mami Kuwamura, Kyoko Kitagawa, Susumu Ueno
Publikováno v:
Journal of Occupational Health. 65