Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Susumu Tomono"'
Autor:
Tatsuya Yamazaki, Kenta Iwasaki, Susumu Tomono, Masaki Imai, Yuko Miwa, Masato Shizuku, Satoshi Ashimine, Kohei Ishiyama, Masanori Inui, Daisuke Okuzaki, Manabu Okada, Takaaki Kobayashi, Sachiko Akashi-Takamura
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110649- (2024)
Summary: Detecting antibodies, particularly those targeting donor human leukocyte antigens in organ transplantation and self-antigens in autoimmune diseases, is crucial for diagnosis and therapy. Radioprotective 105 (RP105), a Toll-like receptor fami
Externí odkaz:
https://doaj.org/article/0003be1738c946f7ace852d1cf4559f3
Autor:
Takahiro Hamoya, Susumu Tomono, Shingo Miyamoto, Gen Fujii, Keiji Wakabayashi, Michihiro Mutoh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Aspirin, a nonsteroidal anti-inflammatory drug, has been proven effective in a clinical trial of carcinogenesis blockade. However, various modes of action have been reported for these effects. Thus, in this study, we aimed to present reasona
Externí odkaz:
https://doaj.org/article/fd867acb2a3e4a9886824fdbe99eb5b2
Autor:
Dina Mourad Saleh, Shengyong Luo, Omnia Hosny Mohamed Ahmed, David B. Alexander, William T. Alexander, Sivagami Gunasekaran, Ahmed M. El-Gazzar, Mohamed Abdelgied, Takamasa Numano, Hiroshi Takase, Makoto Ohnishi, Susumu Tomono, Randa Hussein Abd el Hady, Katsumi Fukamachi, Jun Kanno, Akihiko Hirose, Jiegou Xu, Shugo Suzuki, Aya Naiki-Ito, Satoru Takahashi, Hiroyuki Tsuda
Publikováno v:
Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-21 (2022)
Abstract Background Considering the expanding industrial applications of carbon nanotubes (CNTs), safety assessment of these materials is far less than needed. Very few long-term in vivo studies have been carried out. This is the first 2-year in vivo
Externí odkaz:
https://doaj.org/article/ceeb9dae1f4742e590016f1f99bc6428
Autor:
Azusa Kobayashi, Ayaka Ito, Ibuki Shirakawa, Atsushi Tamura, Susumu Tomono, Hideo Shindou, Per Niklas Hedde, Miyako Tanaka, Naotake Tsuboi, Takuji Ishimoto, Sachiko Akashi-Takamura, Shoichi Maruyama, Takayoshi Suganami
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Accumulating evidence suggests that cholesterol accumulation in leukocytes is causally associated with the development of autoimmune diseases. However, the mechanism by which fatty acid composition influences autoimmune responses remains unclear. To
Externí odkaz:
https://doaj.org/article/15704b94f80744bbb9fe0cc111083c27
Autor:
Tatsuya Yamazaki, Mrityunjoy Biswas, Kouyu Kosugi, Maria Nagashima, Masanori Inui, Susumu Tomono, Hidekazu Takagi, Isao Ichimonji, Fumiaki Nagaoka, Akira Ainai, Hideki Hasegawa, Joe Chiba, Sachiko Akashi-Takamura
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Radioprotective 105 (RP105) (also termed CD180) is an orphan and unconventional Toll-like receptor (TLR) that lacks an intracellular signaling domain. The agonistic anti-RP105 monoclonal antibody (mAb) can cross-link RP105 on B cells, resulting in th
Externí odkaz:
https://doaj.org/article/349c2f98b4804ec392860fc398516433
Autor:
Mao Hagihara, Yasutoshi Kuroki, Tadashi Ariyoshi, Seiya Higashi, Kazuo Fukuda, Rieko Yamashita, Asami Matsumoto, Takeshi Mori, Kaoru Mimura, Naoko Yamaguchi, Shoshiro Okada, Tsunemasa Nonogaki, Tadashi Ogawa, Kenta Iwasaki, Susumu Tomono, Nobuhiro Asai, Yusuke Koizumi, Kentaro Oka, Yuka Yamagishi, Motomichi Takahashi, Hiroshige Mikamo
Publikováno v:
iScience, Vol 23, Iss 1, Pp - (2020)
Summary: Clostridium butyricum MIYAIRI 588 (CBM 588) is a probiotic bacterium that has previously been used to prevent antibiotic-associated diarrhea. However, the underlying mechanism by which CBM 588 protects the gut epithelial barrier remains uncl
Externí odkaz:
https://doaj.org/article/8e25dd9dbcd04684b521ad3f382bc8db
Autor:
Tadashi Ariyoshi, Mao Hagihara, Susumu Tomono, Shuhei Eguchi, Ayaka Minemura, Daiki Miura, Kentaro Oka, Motomichi Takahashi, Yuka Yamagishi, Hiroshige Mikamo
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 1065 (2021)
The gut microbiome is closely related to gut metabolic functions, and the gut microbiome and host metabolic functions affect each other. Clostridium butyricum MIYAIRI 588 (CBM 588) upregulates protectin D1 production in host colon tissue following G
Externí odkaz:
https://doaj.org/article/065b9b7a9d324a26bcca29f72c93672c
Autor:
Susumu Tomono, Noriyuki Miyoshi, Hidemi Shiokawa, Tomoe Iwabuchi, Yasuaki Aratani, Tatsuya Higashi, Haruo Nukaya, Hiroshi Ohshima
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 1, Pp 87-97 (2011)
3β-Hydroxy-5-oxo-5,6-secocholestan-6-al (secosterol-A) and its aldolization product 3β-hydroxy-5β-hydroxy-B-norcholestane-6β-carboxaldehyde (secosterol-B) were recently detected in human atherosclerotic tissues and brain specimens, and they may p
Externí odkaz:
https://doaj.org/article/5482424702e14e988f9812bd9a89217f
Autor:
Sajid Iftekhar Chowdhury, Masanori Inui, Tatsuya Yamazaki, Susumu Tomono, Hidekazu Takagi, Mrityunjoy Biswas, Shin‐Ichiroh Saitoh, Kensuke Miyake, Sachiko Akashi‐Takamura
Publikováno v:
FEBS Letters. 597:1246-1260
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cfaa6bf131383f203cf855d2d612001
https://doi.org/10.1002/1873-3468.14619
https://doi.org/10.1002/1873-3468.14619
Autor:
Mrityunjoy Biswas, Tatsuya Yamazaki, Susumu Tomono, Sivasundaram Karnan, Hidekazu Takagi, Isao Ichimonji, Masanori Inui, Fumiaki Nagaoka, Yoshitaka Hosokawa, Sachiko Akashi‐Takamura
Publikováno v:
FEBS Letters. 596:3211-3231
For its cell surface expression, radioprotective 105 (RP105) - an orphan Toll-like receptor - must form a complex with a soluble glycoprotein called myeloid differentiation 1 (MD-1). The number of RP105-negative cells is significantly increased in pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80952382c2e0e28d3b16738b912b999e
https://doi.org/10.1002/1873-3468.14452
https://doi.org/10.1002/1873-3468.14452