Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Susumu Miyata"'
Autor:
Tomoko Masunaga, Junko Imanishi, Katsuya Nakamura, Eiji Yoshimi, Kanae Kuroda, Fumie Takahashi, Kaoru Yamagami, Seitaro Mutoh, Emi Hamachi, Masako Kuno, Susumu Miyata, Yoshitaka Ohkubo, Yoshiaki Morita, Satoshi Aoki
Publikováno v:
Biochemical Pharmacology. 82:746-754
Nonsteroidal anti-inflammatory drugs (NSAIDs) are now understood to fall into one of two agent classes in clinical use. Traditional NSAIDs inhibit both cyclooxygenases-1 and 2 (COX-1, 2), which act as key enzymes catalyzing the same reaction in the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::998a08d9a53ee103b3972d49aa4c6faa
https://doi.org/10.1016/j.bcp.2011.06.035
https://doi.org/10.1016/j.bcp.2011.06.035
Autor:
Toru Sasaki, Susumu Miyata
Publikováno v:
Mathematical Biosciences. 201:184-194
An estimate of the distance between spots generated by a bacterial colony model is obtained. The model describes the morphogenesis of a spot pattern in colonies of chemotactic strains of Escherichia coli. Asymptotic methods for other cell-chemotaxis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961ab07520e445dbdbebd468a5b602a3
https://doi.org/10.1016/j.mbs.2005.12.007
https://doi.org/10.1016/j.mbs.2005.12.007
Autor:
Yoshitaka Ohkubo, Fusako Nishigaki, Masahiro Neya, Takeshi Ishikawa, Akira Kagayama, Susumu Miyata, Junko Imanishi, Kyoko Minoura, Yoshimasa Imamura, Yoichi Naritomi, Hidetsugu Murai, Seitaro Mutoh, Yoshitaka Hirayama, Tsuyoshi Mizutani
Publikováno v:
British Journal of Pharmacology. 144:133-143
FR255031 (2-[(7S)-7-[5-(4-ethylphenyl)-2-thienyl]-1,1-dioxido-4-(2-pyridinylcarbonyl)hexahydro-1,4-thiazepin-7-yl]-N-hydroxyacetamide) is a novel synthetic matrix metalloproteinase (MMP) inhibitor that inhibits human collagenases (MMP-1, MMP-8 and MM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94f74d94b7c4f2642efbeaa819cb6ea8
https://doi.org/10.1038/sj.bjp.0706054
https://doi.org/10.1038/sj.bjp.0706054
Publikováno v:
British Journal of Pharmacology. 139:927-934
FK506 and cyclosporin A (CsA) are immunosuppressive drugs, that specifically inhibit T-cell activation via calcineurin inhibition. This study was undertaken to investigate whether calcineurin inhibitors exert analgesic actions in rat adjuvant-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee454e86537ac38143263ba4a3bcd48a
https://doi.org/10.1038/sj.bjp.0705310
https://doi.org/10.1038/sj.bjp.0705310
Autor:
Yoshimi Hirasawa-Taniyama, Mie Nishio, Toshio Yamanaka, Kayoko Mihara, Yasuhiro Kita, Kiyotaka Ito, Jiro Seki, Susumu Miyata, Yasuko Kato, Seitaro Mutoh
Publikováno v:
European Journal of Pharmacology. 473:163-169
The antiplatelet and antithrombotic effects of FR171113, 3-(4-chlorophenyl)-2-(2,4-dichlorobenzoylimino)-5-(methoxycarbonyl methylene)-1,3-thiazolidin-4-one, a non-peptide protease-activated receptor 1 (PAR1) antagonist, were evaluated in guinea pigs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0119ba2a2a39f0bccc611289e2a07df
https://doi.org/10.1016/s0014-2999(03)01973-3
https://doi.org/10.1016/s0014-2999(03)01973-3
Autor:
Susumu Miyata, Fusako Nishigaki, Shozo Sakuma, Toshitaka Ohkubo, Toshikazu Ogawa, Toshio Goto
Publikováno v:
European Journal of Pharmacology. 437:123-128
FK506 (Tacrolimus) and cyclosporin A exert their immunosuppressive effects via a common mechanism, calcineurin inhibition, after binding to intracellular proteins termed immunophilins: FK506-binding protein (FKBP) and cyclophilin. In this study, FK50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc685a83800d1f088f7090b077bfac13
https://doi.org/10.1016/s0014-2999(02)01269-4
https://doi.org/10.1016/s0014-2999(02)01269-4
Autor:
Susumu Miyata, Masakatsu Honma
Publikováno v:
INFRASTRUCTURE PLANNING REVIEW. 19:869-874
The purpose of this study is to specify countermeasures in order to improve safety at signalized intersections with a lagging green phase and to evaluate the effectiveness of these countermeasures.From the viewpoint of practical use, concrete counter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e0fdbedba0760167d0983976d005146
https://doi.org/10.2208/journalip.19.869
https://doi.org/10.2208/journalip.19.869
Autor:
Toshio Goto, Yasuko Kato, Yoshitaka Ohkubo, Katsue Magari, Fusako Nishigaki, Tatsuya Sasakawa, Shozo Sakuma, Susumu Miyata
Publikováno v:
British Journal of Pharmacology. 130:1655-1663
The aim of this study was to elucidate the in vitro inhibitory potency of FK506 on production of the inflammatory cytokines, tumour necrosis factor (TNF)-α and interleukin (IL)-1β, with a view to assessing this immunosuppressive agent as a potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c635a167eaf6951ed1734451ed1519c
https://doi.org/10.1038/sj.bjp.0703472
https://doi.org/10.1038/sj.bjp.0703472
Autor:
Jay A. Nadel, Susumu Miyata, André Coste, C. Chapelin, Marianne Gallup, Carol Basbaum, Estelle Escudier, Austin F. Dohrman, Jian Dong Li
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1406(3):251-259
Bacterial infection of the lung is associated with mucin overproduction. In partial explanation of this phenomenon, we recently reported that supernatant from the Gram-negative organism Pseudomonas ( P .) aeruginosa contained an activity that upregul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6335805df7de0e220a11685165cf6f44
Autor:
Austin F. Dohrman, Marianne Gallup, Susumu Miyata, Jay A. Nadel, Alice Prince, Jian Dong Li, James R. Gum, Young S. Kim, Carol Basbaum
Publikováno v:
Proceedings of the National Academy of Sciences. 94:967-972
An unresolved question in cystic fibrosis (CF) research is how mutations of the CF transmembrane conductance regulator, a Cl ion channel, cause airway mucus obstruction leading to fatal lung disease. Recent evidence has linked the CF transmembrane co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f92d264da72a104c36eaf7b7063dc6ee
https://doi.org/10.1073/pnas.94.3.967
https://doi.org/10.1073/pnas.94.3.967