Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Susumu Miyabo"'
Autor:
Fumihiko Sasaki, Ohnishi T, Tsuguhiko Nakai, Shingo Ameshima, Takeshi Ishizaki, Susumu Miyabo, Shigeru Matsukawa
Publikováno v:
European Journal of Pharmacology. 319:49-55
In the current study, Cu2+ was tested for its ability to relax vessels and to accumulate cyclic GMP (cGMP) in rat pulmonary artery employing rat extrapulmonary arterial rings. Cu(2+)-induced relaxation was endothelium and concentration (in the range
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2959938cb3195d9ab2c5ba64fb215c59
https://doi.org/10.1016/s0014-2999(96)00833-3
https://doi.org/10.1016/s0014-2999(96)00833-3
Autor:
T. Ishizaki, Takayuki Ozawa, Susumu Miyabo, N. F. Voelkel, S. Ameshima, K. Shigemori, Tsuguhiko Nakai, M. Hayakawa
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 271:L459-L463
We tested the hypothesis that BQ-123, a novel endothelin type A (ETA) receptor antagonist, protects the lung against leukotoxin 9,10-epoxy-12-octadecenoate (Lx), which causes acute lung injury in animals. In isolated rat lungs perfused with Earle's b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd478ff47ebc2f198f8a0cb9403d79e
https://doi.org/10.1152/ajplung.1996.271.3.l459
https://doi.org/10.1152/ajplung.1996.271.3.l459
Autor:
Takayuki Ozawa, Shigeru Matsukawa, T. Ishizaki, Susumu Miyabo, Tetsuo Sakai, Mika Hayakawa, Tsuguhiko Nakai
Publikováno v:
Free Radical Biology and Medicine. 20:607-612
The present study was carried out to explore the involvement of nitric oxide (NO) and superoxide anion (O2.-) in Leukotoxin (Lx)-induced suppression of mitochondrial respiration. Glutamate- and succinate-dependent oxygen consumption and cytochrome c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47576edca13d78a6c8b4e771e803b0a4
https://doi.org/10.1016/0891-5849(95)02064-0
https://doi.org/10.1016/0891-5849(95)02064-0
Autor:
S. Matsukawa, Takayuki Ozawa, Ohnishi T, T. Ishizaki, Fumihiko Sasaki, Tsuguhiko Nakai, M. Hayakawa, S. Ameshima, T. Sakai, Susumu Miyabo
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 269:L326-L331
To investigate how mitochondrial function was affected in leukotoxin (Lx)-,9,10-epoxy-12-octadecenoate-induced lung injury, lung mitochondria were extracted from isolated perfused rat lung with or without Lx-induced edematous injury. In the lung trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b98c63fed957166834541dac6ac74c
https://doi.org/10.1152/ajplung.1995.269.3.l326
https://doi.org/10.1152/ajplung.1995.269.3.l326
Autor:
Shih-Wen Chang, Takayuki Ozawa, N. F. Voelkel, Tsuguhiko Nakai, T. Ishizaki, K. Shigemori, Susumu Miyabo
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 269:L65-L70
We examined the mechanism of leukotoxin, 9,10-epoxy-12-octadecenoate (Lx)-induced lung injury in blood-free, physiological salt solution-perfused rat lungs under constant flow conditions. Mean pulmonary arterial (Ppa) and pulmonary capillary pressure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d54c177836b604aedb3347dad9eb3fb
https://doi.org/10.1152/ajplung.1995.269.1.l65
https://doi.org/10.1152/ajplung.1995.269.1.l65
Autor:
Toshitaka Tamai, Susumu Miyabo, Tsuguhiko Nakai, Sadao Takahashi, Tokuo Yamamoto, Mitsuyuki Kohno, Jinya Suzuki, Koji Oida
Publikováno v:
Journal of Biological Chemistry. 270:15747-15754
The low-density lipoprotein (LDL) receptor plays a crucial role in cholesterol metabolism. A related protein, designated the very low density lipoprotein (VLDL) receptor, that specifically binds apolipoprotein (apo) E has recently been characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d1e656938570e26d0c466d7952b32f
https://doi.org/10.1074/jbc.270.26.15747
https://doi.org/10.1074/jbc.270.26.15747
Autor:
Takio Hayashi, Koji Oida, Tsuguhiko Nakai, Yusuke Koshino, Yasunori Kutsumi, H. Kato, Susumu Miyabo
Publikováno v:
Biochemical and Biophysical Research Communications. 208:82-88
We determined whether endothelin-1 (ET-1) is associated with glucocorticoid-induced Ca2+ influx into vascular smooth muscle cells by examining the effects of the ETA receptor antagonist FR139317 on dexamethasone-induced 45Ca2+ uptake and dihydropyrid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc4e713449247a9dfa0cf1af670457c
https://doi.org/10.1006/bbrc.1995.1308
https://doi.org/10.1006/bbrc.1995.1308
Autor:
Akihiko Shimada, Sadao Takahashi, Jinya Suzuki, Koji Oida, Tsuguhiko Nakai, Susumu Miyabo, Toshitaka Tamai
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1215:126-132
The metabolism of high-density lipoprotein-associated cholesteryl esters (HDL-CE) in liver cells is not well understood. We studied the possible role of lysosomal and extralysosomal pathways on such metabolism by measuring the uptake and hydrolysis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7461672ca14e22687e3539f2336d83
https://doi.org/10.1016/0005-2760(94)90101-5
https://doi.org/10.1016/0005-2760(94)90101-5