Zobrazeno 1 - 10
of 304
pro vyhledávání: '"Susumu Ishikawa"'
Autor:
Tomoko Kamasaki, Yumi Miyazaki, Susumu Ishikawa, Kazuya Hoshiba, Keisuke Kuromiya, Nobuyuki Tanimura, Yusuke Mori, Motosuke Tsutsumi, Tomomi Nemoto, Ryota Uehara, Shiro Suetsugu, Toshiki Itoh, Yasuyuki Fujita
Publikováno v:
iScience, Vol 24, Iss 9, Pp 102994- (2021)
Summary: At the initial stage of carcinogenesis, cell competition often occurs between newly emerging transformed cells and the neighboring normal cells, leading to the elimination of transformed cells from the epithelial layer. For instance, when Ra
Externí odkaz:
https://doaj.org/article/fa958811e0e047c3bf59653c4f1490e6
Autor:
Takeshi Maruyama, Ayana Sasaki, Sayuri Iijima, Shiyu Ayukawa, Nobuhito Goda, Keisuke Tazuru, Norikazu Hashimoto, Takashi Hayashi, Kei Kozawa, Nanami Sato, Susumu Ishikawa, Tomoko Morita, Yasuyuki Fujita
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101327- (2020)
Summary: Previous studies have revealed that, at the initial step of carcinogenesis, transformed cells are often eliminated from epithelia via cell competition with the surrounding normal cells. In this study, we performed cell competition-based high
Externí odkaz:
https://doaj.org/article/a4da442164934ad3ae49b1f37797f989
Autor:
Hirotaka Watanabe, Kojiro Ishibashi, Hiroki Mano, Sho Kitamoto, Nanami Sato, Kazuya Hoshiba, Mugihiko Kato, Fumihiko Matsuzawa, Yasuto Takeuchi, Takanobu Shirai, Susumu Ishikawa, Yuka Morioka, Toshiaki Imagawa, Kazuyasu Sakaguchi, Suguru Yonezawa, Shunsuke Kon, Yasuyuki Fujita
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3721-3729 (2018)
Summary: p53 is a tumor suppressor protein, and its missense mutations are frequently found in human cancers. During the multi-step progression of cancer, p53 mutations generally accumulate at the mid or late stage, but not in the early stage, and th
Externí odkaz:
https://doaj.org/article/7b3d5f86dea4489d8d609ac4b73d0b9d
Autor:
Tomonori Sugawara, Daisuke Sawada, Sae Yanagihara, Yumeko Aoki, Isao Takehara, Hirosuke Sugahara, Tatsuhiko Hirota, Yasunori Nakamura, Susumu Ishikawa
Publikováno v:
Microorganisms, Vol 8, Iss 2, p 304 (2020)
Despite the fact that gut microbiota is closely associated with obesity, few studies have focused on the influences of paraprobiotics as food ingredients on both obesity prevention and the gut microbial community. In this study, we evaluated the effe
Externí odkaz:
https://doaj.org/article/29acba11d739463d8f85aad112b4f91b
Publikováno v:
Asian Journal of Surgery, Vol 30, Iss 2, Pp 118-121 (2007)
The possibility of a new screening procedure for multiple abdominal solid organs using a mobile helical computed tomography (CT) scanner was evaluated. Methods: A total of 4,543 residents, who were 40 years of age or older, received CT scanning witho
Externí odkaz:
https://doaj.org/article/33bfc518d83d45d5ad708937fbca47ee
Autor:
Masahito Kawabori, Masaki Ito, Ken Kazumata, Kikutaro Tokairin, Kanako C. Hatanaka, Susumu Ishikawa, Kiyohiro Houkin, Miki Fujimura
Publikováno v:
Cerebrovascular Diseases. 52:171-176
Background: Superficial temporal artery (direct) and encephalomyosynangiosis (indirect) revascularization may develop after combined bypass surgery in pediatric patients with moyamoya disease (MMD). However, arterial development varies widely among p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03e4e093888c2e3f849163443ff2e6f8
https://doi.org/10.1159/000526089
https://doi.org/10.1159/000526089
Autor:
Yusuke Mori, Naoka Shiratsuchi, Nanami Sato, Azusa Chaya, Nobuyuki Tanimura, Susumu Ishikawa, Mugihiko Kato, Ikumi Kameda, Shunsuke Kon, Yukinari Haraoka, Tohru Ishitani, Yasuyuki Fujita
Publikováno v:
Current Biology. 32(10):2144-2159
For the maintenance of epithelial homeostasis, various aberrant or dysfunctional cells are actively eliminated from epithelial layers. This cell extrusion process mainly falls into two modes: cell-competition-mediated extrusion and apoptotic extrusio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd6a9e0ab3929385e80d789cbcc63977
http://hdl.handle.net/2433/275396
http://hdl.handle.net/2433/275396
Autor:
Shoko Ito, Keisuke Kuromiya, Miho Sekai, Hiroaki Sako, Kazuhito Sai, Riho Morikawa, Yohei Mukai, Yoko Ida, Moe Anzai, Susumu Ishikawa, Kei Kozawa, Takanobu Shirai, Nobuyuki Tanimura, Kenta Sugie, Junichi Ikenouchi, Motoyuki Ogawa, Isao Naguro, Hidenori Ichijo, Yasuyuki Fujita
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/24/2023, Vol. 120 Issue 43, p1-9, 45p
Autor:
Yusuke Ohba, Yuki Akieda, Takanobu Shirai, Ryutaro Akiyama, Yasuyuki Fujita, Yasuto Takeuchi, Yusuke Toyama, Mihoko Kajita, Takaaki Matsui, Yoichiroh Hosokawa, Masazumi Tada, Yoichiro Fujioka, Keisuke Kuromiya, Sohei Yamada, Susumu Ishikawa, Tohru Ishitani, Yukinari Haraoka, Elisa Vitiello, Rika Narumi, Nobuyuki Tanimura
Publikováno v:
Current biology. 30(4):670-681
When oncogenic transformation or apoptosis occurs within epithelia, the harmful or dead cells are apically extruded from tissues to maintain epithelial homeostasis. However, the underlying molecular mechanism still remains elusive. In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9b559d67182a1c0d61e14548cafae4
http://hdl.handle.net/2115/80478
http://hdl.handle.net/2115/80478
Autor:
Hodaka Sakaue, Yosuke Ashikari, Susumu Ishikawa, Yoko Aizawa, Ibuki Shite, Masahiro Takumi, Yutaka Shimizu, Renzo Luisi, Yuya Yonekura, Ryosuke Higuma, Marco Colella, Kei Maekawa, Toshihiro Takegawa, Chiemi Fujita, Yiyuan Jiang, Yusuke Takahashi, Aiichiro Nagaki, Hiroki Yamashita
Publikováno v:
European Journal of Organic Chemistry. 2020:618-622
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e0019f21dbcdb5eded2f0d7444bc62a
https://doi.org/10.1002/ejoc.201901729
https://doi.org/10.1002/ejoc.201901729