Zobrazeno 1 - 10
of 785
pro vyhledávání: '"Susumu, Seino"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Nobuya Inagaki
Publikováno v:
Journal of Diabetes Investigation, Vol 12, Iss 12, Pp 2106-2107 (2021)
Externí odkaz:
https://doaj.org/article/000deda266304e94b600b619ebb970cf
Publikováno v:
Diabetes. 71:2490-2495
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7049a27ccded6c2b7cc0ac76fe29e5d6
https://doi.org/10.2337/dbi22-0011
https://doi.org/10.2337/dbi22-0011
Publikováno v:
Journal of Diabetes Investigation. Dec2021, Vol. 12 Issue 12, p2106-2107. 2p.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Quan Yingyue, Kenji Sugawara, Harumi Takahashi, Norihide Yokoi, Kento Ohbayashi, Yusaku Iwasaki, Susumu Seino, Wataru Ogawa
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 6, Pp 746-755 (2023)
ABSTRACT Aims/Introduction Imeglimin is a new antidiabetic drug structurally related to metformin. Despite this structural similarity, only imeglimin augments glucose‐stimulated insulin secretion (GSIS), with the mechanism underlying this effect re
Externí odkaz:
https://doaj.org/article/912c73cff87a4997a1cfa1af12cf59fa
Autor:
Guirong Han, Harumi Takahashi, Naoya Murao, Ghupurjan Gheni, Norihide Yokoi, Yoshiyuki Hamamoto, Shun‐ichiro Asahara, Yutaka Seino, Yoshiaki Kido, Susumu Seino
Publikováno v:
Journal of Diabetes Investigation, Vol 12, Iss 6, Pp 920-930 (2021)
Abstract Aims/Introduction Glutamine is the most abundant amino acid in the circulation. In this study, we investigated cell signaling in the amplification of insulin secretion by glutamine. Materials and Methods Clonal pancreatic β‐cells MIN6‐K
Externí odkaz:
https://doaj.org/article/5f31d8d422264d359df183cf9bac2a7e
Autor:
Tomohide Hayami, Norihide Yokoi, Takuro Yamaguchi, Kohei Honda, Naoya Murao, Harumi Takahashi, Shujie Wang, Yusuke Seino, Hideki Kamiya, Daisuke Yabe, Ian R Sweet, Akira Mizoguchi, Jiro Nakamura, Susumu Seino
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 6, Pp 1434-1447 (2020)
Abstract Aims/Introduction Pancreatic islets are heterogenous. To clarify the relationship between islet heterogeneity and incretin action in the islets, we studied gene expression and metabolic profiles of non‐large and enlarged islets of the Zuck
Externí odkaz:
https://doaj.org/article/5890f1d6c1da4df0a98ae5c4ae59e065
Autor:
Naoya Murao, Norihide Yokoi, Harumi Takahashi, Tomohide Hayami, Yasuhiro Minami, Susumu Seino
Publikováno v:
Molecular Metabolism, Vol 55, Iss , Pp 101414- (2022)
Objective: Age is a risk factor for type 2 diabetes (T2D). We aimed to elucidate whether β-cell glucose metabolism is altered with aging and contributes to T2D. Methods: We used senescence-accelerated mice (SAM), C57BL/6J (B6) mice, and ob/ob mice a
Externí odkaz:
https://doaj.org/article/a3936d5cd61f4706a23b2a895c3b8b0d
Autor:
Hiromi Nakai-Shimoda, Tatsuhito Himeno, Tetsuji Okawa, Emiri Miura-Yura, Sachiko Sasajima, Makoto Kato, Yuichiro Yamada, Yoshiaki Morishita, Shin Tsunekawa, Yoshiro Kato, Yusuke Seino, Rieko Inoue, Masaki Kondo, Susumu Seino, Keiko Naruse, Koichi Kato, Hiroki Mizukami, Jiro Nakamura, Hideki Kamiya
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103609- (2022)
Summary: Glucose-responsive ATP-sensitive potassium channels (KATP) are expressed in a variety of tissues including nervous systems. The depolarization of the membrane potential induced by glucose may lead to hyperexcitability of neurons and induce e
Externí odkaz:
https://doaj.org/article/0afe7a666be9414fb5b914b896d61746