Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Susumu, Kageyama"'
Autor:
Masanari Nishida, Akira Sato, Akio Shimizu, Nor Idayu A. Rahman, Akinori Wada, Susumu Kageyama, Hisakazu Ogita
Publikováno v:
Cancer Medicine, Vol 13, Iss 19, Pp n/a-n/a (2024)
ABSTRACT Background and Aims Tumor growth and progression are affected by interactions between tumor cells and stromal cells within the tumor microenvironment. We previously showed that the expression of an integral membrane protein, called stomatin,
Externí odkaz:
https://doaj.org/article/9153fc0a3beb49adb3a4852ef87d04c2
Autor:
Yuki Okinaka, Susumu Kageyama, Toshiyuki Goto, Masahiro Sugimoto, Atsumi Tomita, Yumi Aizawa, Kenichi Kobayashi, Akinori Wada, Akihiro Kawauchi, Yosky Kataoka
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Patients with advanced cancer are frequently burdened with a severe sensation of fatigue called cancer-related fatigue (CRF). CRF is induced at various stages and treatments, such as cachexia and chemotherapy, and reduces the overall surviva
Externí odkaz:
https://doaj.org/article/bacd1532ff0e4961bd027dc5f0783cee
Autor:
Yumiko Saito, Keiko Taniguchi, Hiromi Ii, Mano Horinaka, Susumu Kageyama, Susumu Nakata, Osamu Ukimura, Toshiyuki Sakai
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract γ-Glutamylcyclotransferase (GGCT) is highly expressed in multiple types of cancer tissues and its knockdown suppresses the growth of cancer cells in vitro and in vivo. Although GGCT is a promising target for cancer therapy, the mechanisms u
Externí odkaz:
https://doaj.org/article/636da57f22f844ebac82221b2e349830
Autor:
Takahiro Isono, Takehiro Matsumoto, Masafumi Suzaki, Shigehisa Kubota, Susumu Kageyama, Akihiro Kawauchi, Atuyuki Wada
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Fibrosis is an important pathological mechanism in heart failure (HF) and is associated with poor prognosis. We analyzed fibrosis in HF patients using transcriptomic data. Genes differentially expressed between normal control and congestive
Externí odkaz:
https://doaj.org/article/b3d0005093cc4d99b61e9b89adad46a3
Autor:
Shigehisa Kubota, Tetsuya Yoshida, Susumu Kageyama, Takahiro Isono, Takeshi Yuasa, Junji Yonese, Ryoji Kushima, Akihiro Kawauchi, Tokuhiro Chano
Publikováno v:
World Journal of Surgical Oncology, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Background Accurate prediction of the prognosis of RCC using a single biomarker is challenging due to the genetic heterogeneity of the disease. However, it is essential to develop an accurate system to allow better patient selection for opti
Externí odkaz:
https://doaj.org/article/2604439c6f0f4a88bcf6c2d73aff6600
Autor:
Akinori Wada, Tomoya Terashima, Susumu Kageyama, Tetsuya Yoshida, Mitsuhiro Narita, Akihiro Kawauchi, Hideto Kojima
Publikováno v:
Molecular Therapy: Oncolytics, Vol 12, Iss , Pp 138-146 (2019)
Selective targeting of drugs to tumor cells is a key goal in oncology. Here, we performed an in vivo phage display to identify peptides that specifically target xenografted prostate cancer cells. This yielded three peptide candidates, LN1 (C-TGTPARQ-
Externí odkaz:
https://doaj.org/article/a38b1c0f4d234f11a0fbce5563954994
Publikováno v:
Expert Review of Anticancer Therapy. 23:461-469
At present, the combination of immune checkpoint inhibitors (ICIs) or an ICI and a tyrosine kinase inhibitor (TKI) are the main treatment options as first-line therapy for metastatic renal cell cancer (mRCC). Among them, pembrolizumab plus lenvatinib
Autor:
Susumu Kageyama, Tetsuya Yoshida, Masayuki Nagasawa, Shigehisa Kubota, Keiji Tomita, Kenichi Kobayashi, Ryosuke Murai, Teruhiko Tsuru, Eiki Hanada, Kazuyoshi Johnin, Mitsuhiro Narita, Akihiro Kawauchi
Publikováno v:
BMC Urology, Vol 18, Iss 1, Pp 1-7 (2018)
Abstract Background This study was conducted to determine whether the location of the bladder neck in postoperative cystography predicts recovery of continence after radical prostatectomy. Methods Between 2008 and 2015, 203 patients who underwent lap
Externí odkaz:
https://doaj.org/article/26e7fcdbbaf445839b1c25a960e231ce
Autor:
Takamitsu Inoue, Jun Miyazaki, Daishi Ichioka, Shintaro Narita, Susumu Kageyama, Mikio Sugimoto, Koji Mitsuzuka, Yusuke Shiraishi, Hidefumi Kinoshita, Hironobu Wakeda, Takeshi Nomoto, Eiji Kikuchi, Yoshiyuki Matsui, Keiko Fujie, Tomonori Habuchi, Hiroyuki Nishiyama
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background To compare the prevalence of nephrotoxicity between patients with a solitary-functioning kidney versus those with bilateral-functioning kidneys during the administration of cisplatin-based chemotherapy for advanced urothelial carc
Externí odkaz:
https://doaj.org/article/effec2ab2a374c169b0be57f8ace2d0a
Autor:
Koki Maeda, Susumu Kageyama, Takashi Osafune, Yoshikata Masuda, Shota Nakagawa, Kenji Miki, Shun Esumi, Maiko Kakita‐Kobayashi, Tetsuya Yoshida, Mitsuhiro Narita, Akihiro Kawauchi
Publikováno v:
IJU Case Reports, Vol 2, Iss 6, Pp 327-329 (2019)
Introduction Inappropriate antidiuretic hormone secretion syndrome can be a serious adverse event of cisplatin‐based chemotherapy. Cisplatin had to be changed to other drugs or chemotherapy completely discontinued in earlier reported cases. Case pr
Externí odkaz:
https://doaj.org/article/9f355b506df746e7b7758a91d20fcd63