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pro vyhledávání: '"Sussie Hopkins"'
Autor:
Rane A. Harrison, Olga Rivin, Nikunj Agrawal, Joseph V. Newman, Sussie Hopkins, Marie-Eve Beaudoin, Adam B. Shapiro, Kosalaram Goteti
Publikováno v:
Antimicrobial Agents and Chemotherapy. 57:4816-4824
Several useful properties of liposome-based formulations of various existing antibacterial drugs have been reported. These properties include lower MICs, improved pharmacokinetics, lower toxicity, selective distribution to infected tissues, and enhan
Autor:
Sussie Hopkins, David E. Ehmann, Mark Cronin, Folkert Reck, Adam B. Shapiro, Gregory G. Stone, Thomas J. Dougherty, Michele Johnstone, Asha S. Nayar, Joseph V. Newman
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:4250-4250
The need for new antibiotics that address serious Gram-negative infections is well recognized. Our efforts with a series of novel bacterial type II topoisomerase inhibitors (NBTIs) led to the discovery of NBTI 5463, an agent with improved activity ov