Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Susmitha Vuddagiri"'
Autor:
Susmitha Vuddagiri, Doris Hui Ying Tee, Sandra Sim, Alvin W. Hung, Gang Wang, Thomas H. Keller, Li Hong Tan, Zhiyuan Ke, Anders Poulsen, Nithya Baburajendran, Boping Liu, Vishal Pendharkar, Pearly Shuyi Ng, Jeffrey Hill, Jothi Anantharajan, Joma Joy, May Ann Lee, Zekui Perlyn Kwek, Kanda Sangthongpitag, Sifang Wang, Vithya Manoharan, Klement Foo, Chuhui Huang, Nur Huda Binte Ahmad
Publikováno v:
Bioorganicmedicinal chemistry. 49
AXL is a member of the TAM (TYRO3, AXL, MER) subfamily of receptor tyrosine kinases. It is upregulated in a variety of cancers and its overexpression is associated with poor disease prognosis and acquired drug resistance. Utilizing a fragment-based l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75977880b6d9ca907cbce7ff33cdf1a3
https://pubmed.ncbi.nlm.nih.gov/34600239
https://pubmed.ncbi.nlm.nih.gov/34600239
Autor:
Jeffrey Hill, Joma Joy, Grace Lin, Nurul Dinie, Justina Fulwood, Sin Yin Chew, Xiaoying Koh-Stenta, Sugunavathi Sepramaniam, Xin Hui Chew, Rong Li, Melgious Jin Yan Ang, May Ann Lee, Alex Matter, Weixuan Yu, Zhiyuan Ke, Anna Ngo, Hwa Hwa Chung, Susmitha Vuddagiri, Kanda Sangthongpitag, Klement Foo, Vithya Manoharan, C. S. Brian Chia, Sravanthy Manesh, Esther H. Q. Ong, Nithya Baburajendran, Chuhui Huang, Zekui Perlyn Kwek, John Liang Kuan Wee, Yun Shan Chew, Priya Retna, Thomas H. Keller, Anders Poulsen, Si Si Liew, Choon Bing Low, Vishal Pendharkar
Publikováno v:
ACS Med Chem Lett
[Image: see text] SMYD3 is a histone methyltransferase that regulates gene transcription, and its overexpression is associated with multiple human cancers. A novel class of tetrahydroacridine compounds which inhibit SMYD3 through a covalent mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a957218bb54c41c184fbdaf7cb115a0
https://europepmc.org/articles/PMC6580565/
https://europepmc.org/articles/PMC6580565/
Autor:
Sugunavathi Sepramaniam, Thomas H. Keller, Alex Matter, Xiaoying Koh-Stenta, May Ann Lee, Nurul Dinie, Anders Poulsen, Justina Fulwood, Weixuan Yu, Anna Ngo, Grace Lin, Sin Yin Chew, Xin Hui Chew, Joma Joy, Melgious Jin Yan Ang, Priya Retna, Kanda Sangthongpitag, Nithya Baburajendran, John Liang Kuan Wee, Klement Foo, Jeffrey Hill, Vithya Manoharan, Zekui Perlyn Kwek, Esther H. Q. Ong, Zhiyuan Ke, Rong Li, Chuhui Huang, Hwa Hwa Chung, C. S. Brian Chia, Yun Shan Chew, Susmitha Vuddagiri, Sravanthy Manesh, Vishal Pendharkar, Si Si Liew, Choon Bing Low
Publikováno v:
ACS Medicinal Chemistry Letters. 10:1240-1240
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16e7766113a76f728c12a5194ec42f8e
https://doi.org/10.1021/acsmedchemlett.9b00278
https://doi.org/10.1021/acsmedchemlett.9b00278
Autor:
Susmitha Vuddagiri, Shehzahdi S. Moonshi, Eliana C. Martinez, Jean Yves Dewavrin, Sebastian Beyer, Anna Blocki, Michael Ng, Yingting Wang, Anna G. Goralczyk, Priscilla Peh, Michael Raghunath, Kishore Bhakoo
The limited efficacy of cardiac cell-based therapy is thought to be due to poor cell retention within the myocardium. Hence, there is an urgent need for biomaterials that aid in long-term cell retention. This study describes the development of inject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::117f96eb51075d15deeceeb73a361216
https://hdl.handle.net/11475/12190
https://hdl.handle.net/11475/12190
Autor:
May Ann Lee, Zhiyuan Ke, Sifang Wang, Sharon Xiaodai Lim, Sin Tiong Ong, Vithya Manoharan, Esther H. Q. Ong, Susmitha Vuddagiri, Nacro Kassoum, Kanda Sangthongpitag, Jeffrey Hill
Publikováno v:
Cancer Research. 77:3819-3819
Elevated levels of the phosphorylated m7G cap binding protein, eukaryotic initiation factor 4E (eIF4E) are associated with neoplasia. An observed oncogenic signaling effect upon activation of Erk1/2 or p38 MAPKs in cells is the phosphorylation of eIF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12d4b2ca26e2e6ab2cc9dccc9d6eadb5
https://doi.org/10.1158/1538-7445.am2017-3819
https://doi.org/10.1158/1538-7445.am2017-3819
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