Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Susie Cooke"'
Autor:
Elizabeth Lieschke, Suzanne Dowson, Susie Cooke, Gareth Bryson, Andrew V. Biankin, Kyran El, Anna deFazio, Olga Kondrashova, John Weroha, Justin Bedo, Orla McNally, Iain A. McNeish, Ulla-Maja Bailey, Clare L. Scott, Nadia Traficante, Matthew Wakefield, H. B. Mirza, Holly E. Barker, Rosie Upstill-Goddard, Rosalind Glasspool, Darren Ennis, Cassandra J. Vandenberg, Patricia Roxburgh, Anthony T. Papenfuss, Gayanie Ratnayake, David D.L. Bowtell, Gwo-Yaw Ho
Ovarian carcinosarcoma (OCS) is an aggressive and rare tumour type with limited treatment options. OCS is hypothesised to develop via the combination theory from a single progenitor, resulting in carcinomatous and sarcomatous components, or alternati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc1e598cf60eac20e8ce12ed81c5d9fe
https://doi.org/10.1101/2020.11.24.396796
https://doi.org/10.1101/2020.11.24.396796
Autor:
John Marshall, Dario Beraldi, Susie Cooke, Colin J. McKay, Nigel B. Jamieson, Fraser Duthie, Rosanna Upstill-Goddard, Andrew V. Biankin, C. Ross Carter, Euan J. Dickson, David K. Chang, Stephen R Knight, Stephan Dreyer, Lisa Evers
Publikováno v:
Chinese clinical oncology. 8(2)
Next-generation sequencing is enabling molecularly guided therapy for many cancer types, yet failure rates remain relatively high in pancreatic cancer (PC). The aim of this study is to investigate the feasibility of genomic profiling using endoscopic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b4fc4355c3f76edb450cab33604d836
https://pubmed.ncbi.nlm.nih.gov/31070037
https://pubmed.ncbi.nlm.nih.gov/31070037
Autor:
Jon Stobo, Christine Wilshire, Nigel B. Jamieson, Judith Dixon, David K. Chang, Andrew V. Biankin, Stephan Dreyer, Juan W. Valle, Susie Cooke, Fraser Duthie, Colin J. McKay, Nicola Williams
Publikováno v:
Pancreatology. 20:e15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f0c55689effa7ddc33a328584a71444
https://doi.org/10.1016/j.pan.2020.10.006
https://doi.org/10.1016/j.pan.2020.10.006
Autor:
David K. Chang, Judith Dixon, Andrew V. Biankin, Jon Stobo, Juan W. Valle, Christine Wilshire, Susie Cooke, Fraser Duthie, Nigel B. Jamieson, Colin J. McKay, Stephan Dreyer, Nicola Williams
Publikováno v:
Cancer Research. 80:815-815
Introduction: Pancreatic Cancer (PC) is the 3rd leading cause of cancer death. Precision-Panc UK Consortium was established to accelerate therapeutic development for PC by harmonizing the continuous learning between Discovery, Preclinical and Clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::188f6de08f04411b549a335aea1c62af
https://doi.org/10.1158/1538-7445.am2020-815
https://doi.org/10.1158/1538-7445.am2020-815
Autor:
Elaine McCartney, Martin Eatock, Alanna Morton, Chantevy Pou, Caroline Kelly, David McIntosh, Peter Houston, Anthony J. Chalmers, Susie Cooke, Fiona Thomson, T.R. Jeffry Evans, Claire N. Harrison, A. Duffton, Derek Grose, Miranda Ashton, Jill Graham, Alan Bilsland, Liz-Anne Lewsley, Colin Purcell
Publikováno v:
Journal of Clinical Oncology. 38:709-709
709 Background: Olaparib is a potent inhibitor of PARP-1, which has a critical role in signalling DNA single strand breaks (SSB) as part of the base excision repair pathway, and may have radio-sensitizing effects due to impaired resolution of radiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d892180fc8369736edaf8170c7557b50
https://doi.org/10.1200/jco.2020.38.4_suppl.709
https://doi.org/10.1200/jco.2020.38.4_suppl.709
Autor:
Nigel B. Jamieson, Dave Colville, Jon Stobo, A. Duffton, Reena Ravikumar, Christine Willshire, David McIntosh, Rebecca Goody, Andrew V. Biankin, Janet Graham, Susie Cooke, Derek Grose, Fraser Duthie, Ganesh Radhakrishna, James Paul, Sarah Bradley, Judith Dixon-Hughes, Colin J. McKay, Maria A. Hawkins, David K. Chang
Publikováno v:
Journal of Clinical Oncology. 37:TPS4166-TPS4166
TPS4166 Background: There is increasing evidence suggesting benefit from a neoadjuvant approach to PC. However, the optimal regimen is unclear and will likely require a precision medicine approach, where patient and tumor attributes define therapy. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5b039528d9345a0a4fee86348f4bc6e
https://doi.org/10.1200/jco.2019.37.15_suppl.tps4166
https://doi.org/10.1200/jco.2019.37.15_suppl.tps4166
Autor:
Peter Bailey, Susie Cooke, Nigel B. Jamieson, Andrew V. Biankin, Eirini Lampraki, David K. Chang, Rosie Upstill-Goddard, Stephan Dreyer, Viola Paulus-Hock
Publikováno v:
Journal of Clinical Oncology. 37:285-285
285 Background: Integrated multi-omic analyses revealed 24% of pancreatic cancer (PC) harbor defects in DNA damage response (DDR) and a subgroup demonstrate upregulation in replication stress pathways. DDR defective tumors preferentially respond to D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e195b19c7a81fb1ce987055dc13e43c2
https://doi.org/10.1200/jco.2019.37.4_suppl.285
https://doi.org/10.1200/jco.2019.37.4_suppl.285
Autor:
T.R. Jeffry Evans, Jamie Stobo, Christine Willshire, Colin J. McKay, Nicola Williams, David K. Chang, Judith Dixon-Hughes, Juan W. Valle, Andrew V. Biankin, James Paul, Susie Cooke, Fraser Duthie
Publikováno v:
Journal of Clinical Oncology. 37:TPS460-TPS460
TPS460 Background: A major challenge of lower incidence cancer types is that to make significant advances a network approach is required to coordinate research, generate greater clinical capacity and recruit sufficient patients. This is particularly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30080c6b9eb9655199c682de7982ce54
https://doi.org/10.1200/jco.2019.37.4_suppl.tps460
https://doi.org/10.1200/jco.2019.37.4_suppl.tps460
Autor:
Nigel B. Jamieson, Andrew V. Biankin, Stephan Dreyer, Lisa Evers, Peter Bailey, Elizabeth A. Musgrove, Colin J. McKay, David C. Chang, Susie Cooke, Fraser Duthie
Publikováno v:
HPB. 20:S318
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6af89d34cec9af8d08c610b67c3f67d0
https://doi.org/10.1016/j.hpb.2018.06.342
https://doi.org/10.1016/j.hpb.2018.06.342
Autor:
Susie Cooke, T.R. Jeffry Evans, Derek Grose, Sumitra Mohan, David K. Chang, Janet Graham, Juan W. Valle, Judith Dixon-Hughes, Hannah K. Weir, Andrew V. Biankin, James Paul, Jamie Stobo
Publikováno v:
Journal of Clinical Oncology. 36:TPS4158-TPS4158
TPS4158Background: Platinum-containing regimens (e.g. FOLFIRINOX) have shown survival benefit for pancreatic cancer (PC), with some “exceptional responders”; biomarkers (BM) of response are not well defined. Tumors with mutations in BRCA1/2 and o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cf4e529a3124ff3db2d628e15b313e4
https://doi.org/10.1200/jco.2018.36.15_suppl.tps4158
https://doi.org/10.1200/jco.2018.36.15_suppl.tps4158