Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Susi Heiden"'
Publikováno v:
Kidney & Blood Pressure Research, Vol 41, Iss 6, Pp 770-780 (2016)
Background/Aims: ET-1 has independent effects on blood pressure regulation in vivo, it is involved in tubular water and salt excretion, promotes constriction of smooth muscle cells, modulates sympathetic nerve activity, and activates the liberation o
Externí odkaz:
https://doaj.org/article/67426854317449cbb93df18f88b54b12
Autor:
Susi Heiden, Nicolas Vignon-Zellweger, Shigeru Masuda, Keiko Yagi, Kazuhiko Nakayama, Masashi Yanagisawa, Noriaki Emoto
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88730 (2014)
BACKGROUND: Endothelin-1 participates in the pathophysiology of heart failure. The reasons for the lack of beneficial effect of endothelin antagonists in heart failure patients remain however speculative. The anti-apoptotic properties of ET-1 on card
Externí odkaz:
https://doaj.org/article/54cc3e07a27944f99e35a1d71a9d40d2
Autor:
Lyubov Chaykovska, Karoline von Websky, Jan Rahnenführer, Markus Alter, Susi Heiden, Holger Fuchs, Frank Runge, Thomas Klein, Berthold Hocher
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27861 (2011)
BACKGROUND: Uremic cardiomyopathy contributes substantially to mortality in chronic kidney disease (CKD) patients. Glucagon-like peptide-1 (GLP-1) may improve cardiac function, but is mainly degraded by dipeptidyl peptidase-4 (DPP-4). METHODOLOGY/PRI
Externí odkaz:
https://doaj.org/article/4e4526f9dc6a4249a3ac5af61f79976c
Autor:
Berthold Hocher, Susi Heiden, Karoline von Websky, Ayman M Arafat, Jan Rahnenführer, Markus Alter, Philipp Kalk, Dieter Ziegler, Yvan Fischer, Thiemo Pfab
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17891 (2011)
Liver cirrhosis is often complicated by an impaired renal excretion of water and sodium. Diuretics tend to further deteriorate renal function. It is unknown whether chronic selective adenosine A(1) receptor blockade, via inhibition of the hepatorenal
Externí odkaz:
https://doaj.org/article/808f9c9247834420bad7e29dba1684ba
Autor:
Julia Straube, Matthias Barton, Louisane Desbiens, Rheure A Lopes, Noriaki Emoto, Susi Heiden, Adviye Ergul, Joseph A. Cacioppo, Thomas Leurgans, Masashi Yanagisawa, Danielle Kamato, Raphael Wurm, Nicolas Vignon-Zellweger, Rebecca Moorhouse
Publikováno v:
Emoto, N, Vignon-Zellweger, N, Lopes, R A M, Cacioppo, J, Desbiens, L, Kamato, D, Leurgans, T, Moorhouse, R, Straube, J, Wurm, R, Heiden, S, Ergul, A, Yanagisawa, M & Barton, M 2014, ' 25 Years of endothelin research : The next generation ', Life Sciences, vol. 118, no. 2, pp. 77-86 . https://doi.org/10.1016/j.lfs.2014.07.035
In the past three decades, endothelin and endothelin receptor antagonists have received great scientific and clinical interest, leading to the publication of more than 27,000 scientific articles since its discovery. The Thirteenth International Confe
Autor:
Kazuhiko Nakayama, Suko Adiarto, Noriaki Emoto, Nicolas Vignon-Zellweger, Susi Heiden, Masashi Yanagisawa, Keiko Yagi
Publikováno v:
Life Sciences. 91:651-657
Aims Hypertensive patients develop cardiac hypertrophy and fibrosis with increased stiffness, contractile deficit and altered perfusion. Angiotensin II (AngII) is an important factor in the promotion of this pathology. The effects of AngII are partly
Autor:
Barbara Albrecht-Küpper, Karima Schwab, Franz Theuring, Philipp Kalk, Patrick Seider, Markus Alter, Nicolas Vignon-Zellweger, Juliya Sharkovska, Elodie Kienlen, Katharina Relle, Susi Heiden, Johannes-Peter Stasch, Berthold Hocher
Publikováno v:
Journal of Hypertension. 29:961-970
Background The cardiac nitric oxide and endothelin-1 (ET-1) systems are closely linked and play a critical role in cardiac physiology. The balance between both systems is often disturbed in cardiovascular diseases. To define the cardiac effect of exc
Autor:
Michael Godes, Karoline von Websky, Yuliya Sharkovska, Katharina Relle, Berthold Hocher, Alexander MachA. Mach, Philipp Kalk, Christa Thöne-Reineke, Susi Heiden
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 86:541-545
Activation of the endothelin (ET) system promotes vasoconstriction, inflammation, and fibrosis in various tissues, including the lung. Therefore, ET-1 transgenic mice overexpressing ET-1 develop pulmonary fibrosis in a slow, age-dependent manner. In
Autor:
Dieter Ziegler, Susi Heiden, Yuliya Sharkovska, Berthold Hocher, Katharina Relle, Philipp Kalk, Bielenberg Gw, Michael Godes, Eggert B, Yvan Fischer
Publikováno v:
British Journal of Pharmacology. 151:1025-1032
Background and purpose: Myocardial fibrosis is an unwanted effect associated with chronic renal failure. The adenosine system is involved in cardiac and renal function. Therefore, we investigated the novel selective adenosine A1 receptor antagonist S
Autor:
Kazuhiko Nakayama, Gahan Satwiko, Nur Arfian, Noriaki Emoto, Susi Heiden, Nicolas Vignon-Zellweger, Keiko Yagi, Tran Van Hung, Hary S. Muliawan
Publikováno v:
Life Sciences. 93(25-26)