Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sushma Yarlagadda"'
Publikováno v:
Arthritis & Rheumatism. 64:2964-2974
Objective CD4+ T cells from patients with active lupus have impaired ERK pathway signaling that decreases DNA methyltransferase expression, resulting in DNA demethylation, overexpression of immune genes, and autoimmunity. The ERK pathway defect is du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b05d2c42040a8275b8085498f71a4889
https://doi.org/10.1002/art.34503
https://doi.org/10.1002/art.34503
Autor:
Ailing Wu, Bruce C. Richardson, Anura Hewagama, Dhiman Basu, Faith M. Strickland, Gabriela Gorelik, Robert Hinderer, Sushma Yarlagadda, Mariana J. Kaplan, Ying Liu
Publikováno v:
The Journal of Immunology. 183:3481-3487
T cells from lupus patients have hypomethylated DNA and overexpress genes normally suppressed by DNA methylation that contribute to disease pathogenesis. We found that stimulatory and inhibitory killer cell Ig-like receptor (KIR) genes are aberrantly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2656cf4a4a7134b0f592e1c5dc64b3e
https://doi.org/10.4049/jimmunol.0900034
https://doi.org/10.4049/jimmunol.0900034
Publikováno v:
Genes and immunity
Nature Precedings
Nature Precedings
Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute. Chronic immune stimulation characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8541ee1313a621cee8fb13438ba32a82
https://doi.org/10.1038/npre.2008.2690.1
https://doi.org/10.1038/npre.2008.2690.1
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f24db654cb170db4794a2b82f5a25b4
https://doi.org/10.1096/fasebj.22.1_supplement.825.5
https://doi.org/10.1096/fasebj.22.1_supplement.825.5
Publikováno v:
Arthritis & Rheumatology. 66:769-769
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93b5700ec4031e706a18c9b2a6823b72
https://doi.org/10.1002/art.38395
https://doi.org/10.1002/art.38395