Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sushma Nag"'
Autor:
Marina Moya-Molina, Birthe Dorgau, Emily Flood, Stef J. F. Letteboer, Esben Lorentzen, Jonathan Coxhead, Graham Smith, Ronald Roepman, Sushma Nagaraja Grellscheid, Lyle Armstrong, Majlinda Lako
Publikováno v:
Cell Death and Disease, Vol 15, Iss 10, Pp 1-17 (2024)
Abstract Alternative splicing (AS) is a crucial mechanism contributing to proteomic diversity, which is highly regulated in tissue- and development-specific patterns. Retinal tissue exhibits one of the highest levels of AS. In particular, photorecept
Externí odkaz:
https://doaj.org/article/6ac21c2cb7924f1387437c17d929f6bd
Autor:
Subhash Kulkarni, Monalee Saha, Jared Slosberg, Alpana Singh, Sushma Nagaraj, Laren Becker, Chengxiu Zhang, Alicia Bukowski, Zhuolun Wang, Guosheng Liu, Jenna M Leser, Mithra Kumar, Shriya Bakhshi, Matthew J Anderson, Mark Lewandoski, Elizabeth Vincent, Loyal A Goff, Pankaj Jay Pasricha
Publikováno v:
eLife, Vol 12 (2023)
The enteric nervous system (ENS), a collection of neural cells contained in the wall of the gut, is of fundamental importance to gastrointestinal and systemic health. According to the prevailing paradigm, the ENS arises from progenitor cells migratin
Externí odkaz:
https://doaj.org/article/d74ff71d09fa45de82dc220b51c19e93
Autor:
Aitana Neves, Isabel Cuesta, Erik Hjerde, Terje Klemetsen, David Salgado, Jacques van Helden, Nadim Rahman, Nazeefa Fatima, Nestoras Karathanasis, Pawel Zmora, Wolmar Nyberg Åkerström, Sushma Nagaraja Grellscheid, Zahra Waheed, Niklas Blomberg
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
The COVID-19 pandemic has exemplified the importance of interoperable and equitable data sharing for global surveillance and to support research. While many challenges could be overcome, at least in some countries, many hurdles within the organizatio
Externí odkaz:
https://doaj.org/article/d1e899771f6c4e9c99f8298eee7cfd8c
Publikováno v:
Annals and essences of dentistry. 2:221-224
Giant cell fibroma is a non-neoplastic lesion of fibrous connective tissue origin considered to be a variant of fibroma. It differs significantly from routine fibromas in that its stroma contains very large stellate fibroblasts, making it to be known
Autor:
Ciaran A. J. O’Hare, Vassili G. Matsos, Joseph Newton, Karl Smith, Joel Hochstetter, Ravi Jaiswar, Wunna Kyaw, Aimee McNamara, Zdenka Kuncic, Sushma Nagaraja Grellscheid, Céline Bœhm
Publikováno v:
European Physical Journal C: Particles and Fields, Vol 82, Iss 4, Pp 1-22 (2022)
Abstract We present the first proof-of-concept simulations of detectors using biomaterials to detect particle interactions. The essential idea behind a “DNA detector” involves the attachment of a forest of precisely-sequenced single or double-str
Externí odkaz:
https://doaj.org/article/292f516afeb2449aa09c445d3ad23930
Autor:
Mingqun Lin, Qingming Xiong, Matthew Chung, Sean C. Daugherty, Sushma Nagaraj, Naomi Sengamalay, Sandra Ott, Al Godinez, Luke J. Tallon, Lisa Sadzewicz, Claire Fraser, Julie C. Dunning Hotopp, Yasuko Rikihisa
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-22 (2021)
Abstract Background The genus Ehrlichia consists of tick-borne obligatory intracellular bacteria that can cause deadly diseases of medical and agricultural importance. Ehrlichia sp. HF, isolated from Ixodes ovatus ticks in Japan [also referred to as
Externí odkaz:
https://doaj.org/article/17e831f1fd8140069cf6a9c78d97f21b
Autor:
Mark Raffeld, Zied Abdullaev, Svetlana D. Pack, Liqiang Xi, Sushma Nagaraj, Nicole Briceno, Elizabeth Vera, Stefania Pittaluga, Osorio Lopes Abath Neto, Martha Quezado, Kenneth Aldape, Terri S. Armstrong, Mark R. Gilbert
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-11 (2020)
Abstract We report a novel group of clinically aggressive spinal cord ependymomas characterized by Grade III histology, MYCN amplification, an absence of NF2 alterations or other recurrent pathogenic mutations, and a unique methylation classifier pro
Externí odkaz:
https://doaj.org/article/2c82e008f5634732984ad61c925220af
Autor:
Maria Georgiou, Chunbo Yang, Robert Atkinson, Kuan‐Ting Pan, Adriana Buskin, Marina Moya Molina, Joseph Collin, Jumana Al‐Aama, Franziska Goertler, Sebastian E. J. Ludwig, Tracey Davey, Reinhard Lührmann, Sushma Nagaraja‐Grellscheid, Colin A. Johnson, Robin Ali, Lyle Armstrong, Viktor Korolchuk, Henning Urlaub, Sina Mozaffari‐Jovin, Majlinda Lako
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 3, Pp n/a-n/a (2022)
Abstract Introduction Mutations in pre‐mRNA processing factor 31 (PRPF31), a core protein of the spliceosomal tri‐snRNP complex, cause autosomal‐dominant retinitis pigmentosa (adRP). It has remained an enigma why mutations in ubiquitously expre
Externí odkaz:
https://doaj.org/article/d0deada325104e39a8d523ef7fabc4d6
Autor:
Chunbo Yang, Maria Georgiou, Robert Atkinson, Joseph Collin, Jumana Al-Aama, Sushma Nagaraja-Grellscheid, Colin Johnson, Robin Ali, Lyle Armstrong, Sina Mozaffari-Jovin, Majlinda Lako
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Retinitis pigmentosa (RP) is the most common inherited retinal disease characterized by progressive degeneration of photoreceptors and/or retinal pigment epithelium that eventually results in blindness. Mutations in pre-mRNA processing factors (PRPF3
Externí odkaz:
https://doaj.org/article/f68e9ad4e4a948848fba0445af61964a
Autor:
Mikolaj Ogrodnik, Satomi Miwa, Tamar Tchkonia, Dina Tiniakos, Caroline L. Wilson, Albert Lahat, Christoper P. Day, Alastair Burt, Allyson Palmer, Quentin M. Anstee, Sushma Nagaraja Grellscheid, Jan H J. Hoeijmakers, Sander Barnhoorn, Derek A. Mann, Thomas G. Bird, Wilbert P. Vermeij, James L. Kirkland, João F. Passos, Thomas von Zglinicki, Diana Jurk
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Non-alcoholic fatty liver disease is more common among older individuals. Here, the authors show that senescent cells in the liver promote fat accumulation and steatosis in the liver, and that clearance of senescent cells reduces hepatic steatosis in
Externí odkaz:
https://doaj.org/article/59da7366bd92469288a45b90a4b396f9