Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sushma A. Ogram"'
Publikováno v:
Virology. 485:492-501
The differential use of protein precursors and their products is a key strategy used during poliovirus replication. To characterize the role of protein precursors during replication, we examined the complementation profiles of mutants that inhibited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fb312ec387e4c5f59b84ca249741b8
https://doi.org/10.1016/j.virol.2015.07.018
https://doi.org/10.1016/j.virol.2015.07.018
Autor:
James B. Flanegan, Sushma A. Ogram
Publikováno v:
Current Opinion in Virology. 1:339-346
The genomic RNA of poliovirus and closely related picornaviruses perform templated and non-templated functions during viral RNA replication. The non-templated functions are mediated by cis-active RNA sequences that bind viral and cellular proteins to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420581c7a8dfc9d6c19216f1e12e4f9e
https://doi.org/10.1016/j.coviro.2011.09.005
https://doi.org/10.1016/j.coviro.2011.09.005
Publikováno v:
Virology. 397(1):14-22
In this study, we showed that the 5′CL-PCBP complex, 3′ poly(A) tail and viral protein 2Apro are all required for optimal translation of PV RNA. The 2Apro-mediated stimulation of translation was observed in the presence or absence of both the 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c26295ae0090cbbd078b47f3616267b
Autor:
James B. Flanegan, B. Joan Morasco, Sushma A. Ogram, Nora M. Chapman, Nidhi Sharma, Allyn Spear
Publikováno v:
Virology. 393(2):238-249
Using cell-free reactions, we investigated the role of the 5' cloverleaf (5'CL) and associated C-rich sequence in Coxsackievirus B3 RNA replication. We showed that the binding of poly(C) binding protein (PCBP) to the C-rich sequence was the primary d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1260587d90c51dd219fdf0926d9e135
Publikováno v:
Virology. 345(2):509-519
The precise relationship between the length of the 3' poly(A) tail and the replication and infectivity of poliovirus RNA was examined in this study. With both poly(A)(11) and poly(A)(12) RNAs, negative-strand synthesis was 1-3% of the level observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edce00c08d0f15acf8cc3489174b4263
Publikováno v:
Oncogene. 16:3387-3396
Elevated levels of high mobility group (HMG) nonhistone chromosomal proteins I and Y, alternatively spliced members of the HMG-I(Y) family of architectural transcription factors, have been linked with human cancer and with neo-plastic and metastatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6043676b7907de81e664daed5b6e30d
https://doi.org/10.1038/sj.onc.1201888
https://doi.org/10.1038/sj.onc.1201888
Autor:
Sushma Abraham Ogram, Raymond Reeves
Publikováno v:
Journal of Biological Chemistry. 270:14235-14242
The human HMG-I/Y gene, encoding the non-histone "high mobility group" proteins HMG-I and HMG-Y, is transcriptionally activated in human K562 erythroleukemia cells by treatment with 12-O-tetradecanoylphorbol-13-acetate (TPA). TPA treatment induces di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6875abe282bae7685c6878300ab24559
https://doi.org/10.1074/jbc.270.23.14235
https://doi.org/10.1074/jbc.270.23.14235
Autor:
Christy K. Jurgens, Sushma A. Ogram, David J. Barton, James B. Flanegan, B. Joan Morasco, Nidhi Sharma
Publikováno v:
Virology. (2):346-357
Poliovirus 2A(pro) is required for the inhibition of host cell protein synthesis and efficient viral replication. We investigated the role of 2A(pro) in regulating viral RNA stability, translation and replication in HeLa S10 reactions. The protease a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e764b08cbb0a40c4c24ede55336bb3b
Publikováno v:
Virology. :87-97
The mechanism of amiloride inhibition of Coxsackievirus B3 (CVB3) and poliovirus type 1 (PV1) RNA replication was investigated using membrane-associated RNA replication complexes. Amiloride was shown to inhibit viral RNA replication and VPgpUpU synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6bb358d550285bdf48b0ad28cf9a0f1