Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Sushilla Van Schoonhoven"'
Autor:
Lisa Gabler, Carola Nadine Jaunecker, Sonja Katz, Sushilla van Schoonhoven, Bernhard Englinger, Christine Pirker, Thomas Mohr, Petra Vician, Mirjana Stojanovic, Valentin Woitzuck, Anna Laemmerer, Dominik Kirchhofer, Lisa Mayr, Mery LaFranca, Friedrich Erhart, Sarah Grissenberger, Andrea Wenninger-Weinzierl, Caterina Sturtzel, Barbara Kiesel, Alexandra Lang, Brigitte Marian, Bettina Grasl-Kraupp, Martin Distel, Julia Schüler, Johannes Gojo, Michael Grusch, Sabine Spiegl-Kreinecker, Daniel J. Donoghue, Daniela Lötsch, Walter Berger
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Glioblastoma (GBM) is characterized by a particularly invasive phenotype, supported by oncogenic signals from the fibroblast growth factor (FGF)/ FGF receptor (FGFR) network. However, a possible role of FGFR4 remained elusive so far. Several
Externí odkaz:
https://doaj.org/article/a09b2bdbe34d4252a9676846e4f372c1
Autor:
Alessio Terenzi, Mery La Franca, Sushilla van Schoonhoven, Rostyslav Panchuk, Álvaro Martínez, Petra Heffeter, Redding Gober, Christine Pirker, Petra Vician, Christian R. Kowol, Rostyslav Stoika, Luca Salassa, Jürgen Rohr, Walter Berger
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-13 (2021)
Landomycins are promising anti-cancer agents with the potential to bypass common resistance pathways, but their mechanism of action remains incompletely understood. Here a mechanism is proposed involving intracellular sequential thiol-Michael and oxi
Externí odkaz:
https://doaj.org/article/bdb5050705c84bce940244077ea65781
Autor:
Lisa Gabler, Daniela Lötsch, Dominik Kirchhofer, Sushilla van Schoonhoven, Hannah M. Schmidt, Lisa Mayr, Christine Pirker, Katharina Neumayer, Carina Dinhof, Lucia Kastler, Amedeo A. Azizi, Christian Dorfer, Thomas Czech, Christine Haberler, Andreas Peyrl, Rajiv Kumar, Irene Slavc, Sabine Spiegl-Kreinecker, Johannes Gojo, Walter Berger
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract The BRAF gene and the TERT promoter are among the most frequently altered genomic loci in low-grade (LGG) and high-grade-glioma (HGG), respectively. The coexistence of BRAF and TERT promoter aberrations characterizes a subset of aggressive g
Externí odkaz:
https://doaj.org/article/0d0f5c425b5246679d273f73084e3798
Autor:
Bernhard Englinger, Sebastian Kallus, Julia Senkiv, Daniela Heilos, Lisa Gabler, Sushilla van Schoonhoven, Alessio Terenzi, Patrick Moser, Christine Pirker, Gerald Timelthaler, Walter Jäger, Christian R. Kowol, Petra Heffeter, Michael Grusch, Walter Berger
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-13 (2017)
Abstract Background Studying the intracellular distribution of pharmacological agents, including anticancer compounds, is of central importance in biomedical research. It constitutes a prerequisite for a better understanding of the molecular mechanis
Externí odkaz:
https://doaj.org/article/ab5f3166b8d14e12903480ffb0754129
Autor:
Bernd Kubista, Thomas Schoefl, Lisa Mayr, Sushilla van Schoonhoven, Petra Heffeter, Reinhard Windhager, Bernhard K. Keppler, Walter Berger
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-13 (2017)
Abstract Background Osteosarcoma is the most frequent primary malignant bone tumor. Although survival has distinctly increased due to neoadjuvant chemotherapy in the past, patients with metastatic disease and poor response to chemotherapy still have
Externí odkaz:
https://doaj.org/article/572afccbcf204f4ba0e2b876faa027d7
Autor:
Daniela Heilos, Yelko Rodríguez-Carrasco, Bernhard Englinger, Gerald Timelthaler, Sushilla van Schoonhoven, Michael Sulyok, Simon Boecker, Roderich D. Süssmuth, Petra Heffeter, Rosa Lemmens-Gruber, Rita Dornetshuber-Fleiss, Walter Berger
Publikováno v:
Toxins, Vol 9, Iss 9, p 258 (2017)
Recently, in vitro anti-cancer properties of beauvericin, a fungal metabolite were shown in various cancer cell lines. In this study, we assessed the specificity of this effect by comparing beauvericin cytotoxicity in malignant versus non-malignant c
Externí odkaz:
https://doaj.org/article/8be93a9b7e0340beb6b958a71b4a11c9
Autor:
Walter Berger, Balazs Hegedüs, Michael Grusch, Balazs Döme, Walter Klepetko, Judit Ozsvar, Anita Rozsas, Viktoria Laszlo, Thomas Klikovits, Sushilla van Schoonhoven, Kushtrim Kryeziu, Petra Heffeter, Karin Schelch, Yawen Dong, Christine Pirker, Mir A. Hoda
Supplementary Figure S1: Sensitivity of pleural mesothelioma cell models to trabectedin and impact of the histological origin Supplementary Figure S2: Impact of trabectedin on the migratory potential of pleural mesothelioma cell models Supplementary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94caab1f76b3f8eb6ba5fadcf8311df
https://doi.org/10.1158/1535-7163.22504230.v1
https://doi.org/10.1158/1535-7163.22504230.v1
Autor:
Walter Berger, Balazs Hegedüs, Michael Grusch, Balazs Döme, Walter Klepetko, Judit Ozsvar, Anita Rozsas, Viktoria Laszlo, Thomas Klikovits, Sushilla van Schoonhoven, Kushtrim Kryeziu, Petra Heffeter, Karin Schelch, Yawen Dong, Christine Pirker, Mir A. Hoda
Supplementary Table S1: Source, background, histology of the tumor and sensitivity towards trabectedin and cisplatin of all mesothelial and mesothelioma cell models used Supplementary Table S2: Cell death-related genes most differently expressed betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a91be2084472e9525e0b201853efdb
https://doi.org/10.1158/1535-7163.22504227.v1
https://doi.org/10.1158/1535-7163.22504227.v1
Autor:
Walter Berger, Balazs Hegedüs, Michael Grusch, Balazs Döme, Walter Klepetko, Judit Ozsvar, Anita Rozsas, Viktoria Laszlo, Thomas Klikovits, Sushilla van Schoonhoven, Kushtrim Kryeziu, Petra Heffeter, Karin Schelch, Yawen Dong, Christine Pirker, Mir A. Hoda
Trabectedin synergizes with the bcl-2 inhibitor obatoclax in a pleural mesothelioma cell model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58af23d12bd25d099689059d11f5849
https://doi.org/10.1158/1535-7163.22504224.v1
https://doi.org/10.1158/1535-7163.22504224.v1
Autor:
Bernhard Englinger, Salvatore Piscuoglio, Jean Rommelaere, Dominik Witzigmann, Sushilla van Schoonhoven, Walter Berger, David Grünig, Xue-Ting Tran, Patrick Hauswirth, Susanne H. Schenk, Stephan Krähenbühl, Jörg Huwyler, Luigi Terracciano, Manuela Lanzafame, Philip Grossen, Cristina Quintavalle, Jürg P. F. Nüesch, Luca Quagliata
Publikováno v:
Journal of Controlled Release. 334:138-152
Hepatocellular carcinoma (HCC) is related to increasing incidence rates and poor clinical outcomes due to lack of efficient treatment options and emerging resistance mechanisms. The aim of the present study is to exploit a non-viral gene therapy enab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bad076640ca4aef3965956cab86bff0
https://doi.org/10.1016/j.jconrel.2021.04.023
https://doi.org/10.1016/j.jconrel.2021.04.023