Výsledky vyhledávání - "Sushil N. Benke"

Potent Antimicrobial Activity of Lipidated Short α,γ-Hybrid Peptides

Autor: Sushil N. Benke, Hirekodathakallu V. Thulasiram, Hosahudya N. Gopi

Publikováno v: ChemMedChem. 12(19)

We are reporting potent antimicrobial activity of alpha,gamma-hybrid lipopeptides constituted with 1:1 alternating alpha- and gamma-amino acids. Along with their potent antimicrobial activity against various Gram positive and Gram negative bacteria,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c719d3ed39e558c1f5453e360023e1
https://pubmed.ncbi.nlm.nih.gov/28834198

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Engineering polypeptide folding through trans double bonds: transformation of miniature β-meanders to hybrid helices

Autor: Sushil N. Benke, K. Muruga Poopathi Raja, Mothukuri Ganesh Kumar, Hosahudya N. Gopi

Publikováno v: Chemical Communications. 51:13397-13399

Utilization of conjugated double bonds to engineer the novel folded miniature β-meander type structures, single step transformation of miniature β-meanders into ααγ(4)-hybrid peptide 10/12-helices using catalytic hydrogenation, their solution an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72cf42ee9b400a46223b2865bab56ce3
https://doi.org/10.1039/c5cc04523a

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Self-assembly to function: design, synthesis, and broad spectrum antimicrobial properties of short hybrid E-vinylogous lipopeptides

Autor: Prabhakar Lal Srivastava, Sushil N. Benke, Hosahudya N. Gopi, Narem Nagendra, Hirekodathakallu V. Thulasiram, S. Shiva Shankar

Publikováno v: Journal of medicinal chemistry. 56(21)

Nonribosomal E-vinylogous γ-amino acids are widely present in many peptide natural products and have been exploited as inhibitors for serine and cysteine proteases. Here, we are reporting the broad spectrum antimicrobial properties and self-assemble

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc57c5added87e3362bb422d2fd8a92
https://pubmed.ncbi.nlm.nih.gov/24117107

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A facile synthesis and crystallographic analysis of N-protected β-amino alcohols and short peptaibols

Autor: Hosahudya N. Gopi, Sachitanand M. Mali, Sushil N. Benke, Anupam Bandyopadhyay, Sandip V. Jadhav

Publikováno v: Organic & Biomolecular Chemistry. 9:4182

A facile, efficient and racemization-free method for the synthesis of N-protected β-amino alcohols and peptaibols using N-hydroxysuccinimide active esters is described. Using this method, dipeptide, tripeptide and pentapeptide alcohols were isolated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eed832b34009a51246769c852a5b232
https://doi.org/10.1039/c0ob01226b

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