Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sushil, Devkota"'
Autor:
Zhiqian Li, Nimi Marcel, Sushil Devkota, Ankush Auradkar, Stephen M. Hedrick, Valentino M. Gantz, Ethan Bier
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
CRISPR-based genetic elements can copy themselves across host genomes. Here the authors introduce CopyCatcher, a gene-drive related system for detecting and quantifying somatic gene conversion events.
Externí odkaz:
https://doaj.org/article/b94ecd06f7bb42bcb6d8bcbcc6d0a9f1
Autor:
Hye Ji Choi, Hyun Jae Lee, Jin Young Choi, Ik Hyun Jeon, Byunghwa Noh, Sushil Devkota, Han-Woong Lee, Seong Kug Eo, Jae Young Choi, Min Goo Lee, Jinsei Jung
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 188-197 (2020)
The His723Arg (H723R) mutation in SLC26A4, encoding pendrin, is the most prevalent mutation in East Asia, resulting in DFNB4, an autosomal recessive type of genetic hearing loss. Although the main pathological mechanism of H723R was identified as a p
Externí odkaz:
https://doaj.org/article/03023b2578ba4536a741af8aa7224e62
Autor:
Qi-Gang Zhou, Meng-Ying Liu, Han-Woong Lee, Fuyuki Ishikawa, Sushil Devkota, Xin-Ru Shen, Xin Jin, Hai-Yin Wu, Zhigang Liu, Xiao Liu, Xun Jin, Hai-Hui Zhou, Eun Jeoung Ro, Jing Zhang, Yu Zhang, Yu-Hui Lin, Hoonkyo Suh, Dong-Ya Zhu
Publikováno v:
Stem Cell Reports, Vol 9, Iss 2, Pp 543-556 (2017)
Summary: The molecular mechanism of memory formation remains a mystery. Here, we show that TERT, the catalytic subunit of telomerase, gene knockout (Tert−/−) causes extremely poor ability in spatial memory formation. Knockdown of TERT in the dent
Externí odkaz:
https://doaj.org/article/c0c9bcb43b7444c38e4a28df9e4787e2
Autor:
Han-Woong Lee, Young Yil Bahk, Kunsoo Rhee, Jaehoon Lee, Jusik Roh, Sushil Devkota, Hye Jin Kim, Young Hoon Sung
Supplementary Table 1 from Pierce1, a Novel p53 Target Gene Contributing to the Ultraviolet-Induced DNA Damage Response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b38584739df30f738c47ab457aaa273
https://doi.org/10.1158/0008-5472.22386818
https://doi.org/10.1158/0008-5472.22386818
Autor:
Han-Woong Lee, Young Yil Bahk, Kunsoo Rhee, Jaehoon Lee, Jusik Roh, Sushil Devkota, Hye Jin Kim, Young Hoon Sung
Supplementary Figure Legends 1-6 from Pierce1, a Novel p53 Target Gene Contributing to the Ultraviolet-Induced DNA Damage Response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1295eb65954e6e713bd4cce1dc7c30
https://doi.org/10.1158/0008-5472.22386824.v1
https://doi.org/10.1158/0008-5472.22386824.v1
Autor:
Rina M Mbofung, Xingyue Zong, Erika Varady, Alan M Williams, Ken L Hayama, Yijia Pan, Sushil Devkota, Brian Groff, Miguel Meza, Thomas Dailey, Tom Lee, Lilly Wong, Sarah Cooley, Ryan Bjordahl, Jode P Goodridge, Bahram Valamehr
Publikováno v:
Blood. 140:7388-7389
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3e0bcd62df03181b69063973afe0037
https://doi.org/10.1182/blood-2022-169817
https://doi.org/10.1182/blood-2022-169817
Autor:
Young-Hoon Sung, Seungeon Lee, Yaechan Song, Do Young Hyeon, Jae-Hoon Lee, Yujin Kim, Jae-il Roh, Hye Jeong Kim, Bomin Park, Yonghwan Kim, Taewook Nam, Jahyun Oh, Han Woong Lee, Daehee Hwang, Sushil Devkota
Publikováno v:
Oncogene
KRAS-mutant non-small cell lung cancer (NSCLC) is a major lung cancer subtype that leads to many cancer-related deaths worldwide. Although numerous studies on KRAS-mutant type NSCLC have been conducted, new oncogenic or tumor suppressive genes need t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074976032f0b810b62c65820edc1c7b1
https://doi.org/10.1038/s41388-020-01399-5
https://doi.org/10.1038/s41388-020-01399-5
Autor:
Jae Young Choi, Byunghwa Noh, Seong Kug Eo, Hye Ji Choi, Sushil Devkota, Hyunjae Lee, Min Goo Lee, Jin Young Choi, Han Woong Lee, Ik Hyun Jeon, Jinsei Jung
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 188-197 (2020)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
The His723Arg (H723R) mutation in SLC26A4, encoding pendrin, is the most prevalent mutation in East Asia, resulting in DFNB4, an autosomal recessive type of genetic hearing loss. Although the main pathological mechanism of H723R was identified as a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28029b0ccb0bc565f5fbbd5fbd0dc053
http://www.sciencedirect.com/science/article/pii/S2329050119301445
http://www.sciencedirect.com/science/article/pii/S2329050119301445
Publikováno v:
Science Advances
Description
Full replacement of D. melanogaster pb Hox locus with D. mimica pb locus produces mouthparts with similarities to D. mimica.
Hox genes determine positional codes along the head-to-tail axis. Here, we replaced the entire Drosophi
Full replacement of D. melanogaster pb Hox locus with D. mimica pb locus produces mouthparts with similarities to D. mimica.
Hox genes determine positional codes along the head-to-tail axis. Here, we replaced the entire Drosophi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f80e16cd01d7303dbeabd56ccf2c5c0
https://doi.org/10.1126/sciadv.abk1003
https://doi.org/10.1126/sciadv.abk1003
Autor:
Nimi Marcel, Stephen M. Hedrick, Ethan Bier, Valentino M. Gantz, Sushil Devkota, Zhiqian Li, Ankush Auradkar
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature communications, vol 12, iss 1
Nature communications, vol 12, iss 1
CRISPR-based active genetic elements, or gene-drives, copied via homology-directed repair (HDR) in the germline, are transmitted to progeny at super-Mendelian frequencies. Active genetic elements also can generate widespread somatic mutations, but th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f893313d7573de0ccaf880df868496
https://doi.org/10.1038/s41467-021-22927-1
https://doi.org/10.1038/s41467-021-22927-1