Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Susheel Vijayraghavan"'
Autor:
Susheel Vijayraghavan, Stefan Everling
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2021)
Neuromodulation by acetylcholine plays a vital role in shaping the physiology and functions of cerebral cortex. Cholinergic neuromodulation influences brain-state transitions, controls the gating of cortical sensory stimulus responses, and has been s
Externí odkaz:
https://doaj.org/article/fb4493ea14984b5d93e7f024c823c435
Publikováno v:
Cell Reports, Vol 16, Iss 3, Pp 805-816 (2016)
Studies of neuromodulation of spatial short-term memory have shown that dopamine D1 receptor (D1R) stimulation in dorsolateral prefrontal cortex (DLPFC) dose-dependently modulates memory activity, whereas D2 receptors (D2Rs) selectively modulate acti
Externí odkaz:
https://doaj.org/article/23917630b6a0452586de062fd7877805
Publikováno v:
Frontiers in Neural Circuits, Vol 11 (2017)
The prefrontal cortex (PFC) is indispensable for several higher-order cognitive and executive capacities of primates, including representation of salient stimuli in working memory (WM), maintenance of cognitive task set, inhibition of inappropriate r
Externí odkaz:
https://doaj.org/article/ad58b933565e43ccae8e4b1c92ae1d08
Publikováno v:
Cell Reports, Vol 16, Iss 3, Pp 805-816 (2016)
Brain and Mind Institute Researchers' Publications
Brain and Mind Institute Researchers' Publications
SummaryStudies of neuromodulation of spatial short-term memory have shown that dopamine D1 receptor (D1R) stimulation in dorsolateral prefrontal cortex (DLPFC) dose-dependently modulates memory activity, whereas D2 receptors (D2Rs) selectively modula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9acd0cffb6db8b89c5b51033e5ede96f
https://doi.org/10.1016/j.celrep.2016.06.031
https://doi.org/10.1016/j.celrep.2016.06.031
Autor:
Kathy Peng, Anna Kata, Faith Lin, Constantinos D. Paspalas, Lisette Roman, Gyorgy Lur, Susheel Vijayraghavan, Lindsay Boven, Michael J. Higley, Yang Yang, Amy F.T. Arnsten, Min Wang, Brian P. Ramos, Daeyeol Lee, Nao J. Gamo
Publikováno v:
Biological psychiatry, vol 78, iss 12
Background Psychiatric disorders such as schizophrenia are worsened by stress, and working memory deficits are often a central feature of illness. Working memory is mediated by the persistent firing of prefrontal cortical (PFC) pyramidal neurons. Str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340e3606e551cc07f492e6b15ed2a9c9
https://doi.org/10.1016/j.biopsych.2015.01.009
https://doi.org/10.1016/j.biopsych.2015.01.009
Publikováno v:
Brain and Mind Institute Researchers' Publications
Acetylcholine is released in the prefrontal cortex (PFC) and is a key modulator of cognitive performance in primates. Cholinergic stimulation has been shown to have beneficial effects on performance of cognitive tasks, and cholinergic receptors are b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2bb63f856199ab3b6dad53fc6e4bec
https://ir.lib.uwo.ca/brainpub/1102
https://ir.lib.uwo.ca/brainpub/1102
Publikováno v:
Brain and Mind Institute Researchers' Publications
Summary Acetylcholine release in the prefrontal cortex (PFC), acting through muscarinic receptors, has an essential role in regulating flexible behavior and working memory (WM). General muscarinic receptor blockade disrupts PFC WM representations, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e944a67e7ec4c5c51238b5d312df35c0
https://pubmed.ncbi.nlm.nih.gov/29953868
https://pubmed.ncbi.nlm.nih.gov/29953868
Publikováno v:
Brain and Mind Institute Researchers' Publications
Maintenance of context is necessary for execution of appropriate responses to diverse environmental stimuli. The dorsolateral prefrontal cortex (DLPFC) plays a pivotal role in executive function, including working memory and representation of abstrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886f7a829b1af698968a52edaac922c0
https://pubmed.ncbi.nlm.nih.gov/26658860
https://pubmed.ncbi.nlm.nih.gov/26658860
Autor:
Constantinos D. Paspalas, Arthur A. Simen, Susheel Vijayraghavan, Avis R. Brennan, Alvaro Duque, Eric Nou, David A. McCormick, Amy F.T. Arnsten, Yousheng Shu, James A. Mazer, Anne G Dudley, Min Wang, Brian P. Ramos
Publikováno v:
Cell. 129(2):397-410
Spatial working memory (WM; i.e., "scratchpad" memory) is constantly updated to guide behavior based on representational knowledge of spatial position. It is maintained by spatially tuned, recurrent excitation within networks of prefrontal cortical (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0a6f3f637b2e4f81119b7024479a9a
Publikováno v:
Science. 303:853-856
Prefrontal neurons engaged by working memory tasks express a sequence of phasic and tonic activations linked to a train of sensory, mnemonic, and response-related events. Here, we report that the dopamine D2 receptor selectively modulates the neural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9148d158d14fccb5321126fa9c9d250f
https://doi.org/10.1126/science.1091162
https://doi.org/10.1126/science.1091162