Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sushant Lakkadwala"'
Publikováno v:
Polymers, Vol 7, Iss 8, Pp 1510-1521 (2015)
The purpose of this study was to investigate the effects of size and type of incorporated model molecules on the polymer degradation and release profile from thermosensitive triblock copolymer based controlled delivery systems. In vitro release of th
Externí odkaz:
https://doaj.org/article/fc445451cb334587836cad4d35841d2f
Publikováno v:
J Pharmacol Exp Ther
The development of neuropharmaceutical gene delivery systems requires strategies to obtain efficient and effective brain targeting as well as blood-brain barrier (BBB) permeability. A brain-targeted gene delivery system based on a transferrin (Tf) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbab3531d13f20c3f09534cfa7cac3c5
https://doi.org/10.1124/jpet.119.264127
https://doi.org/10.1124/jpet.119.264127
Publikováno v:
International Journal of Nanomedicine. 14:6497-6517
Background The potential of gene therapy for treatment of neurological disorders can be explored using designed lipid-based nanoparticles such as liposomes, which have demonstrated ability to deliver nucleic acid to brain cells. We synthesized liposo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b06649b215e87f31b4e56554c2f2e7e
https://doi.org/10.2147/ijn.s215941
https://doi.org/10.2147/ijn.s215941
Autor:
Jagdish Singh, Sushant Lakkadwala
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 173:27-35
Glioma is a highly malignant tumor that starts in the glial cells of brain. Tumor cells reproduce quickly and infiltrate rapidly in high grade glioma. Permeability of chemotherapeutic agents into brain is restricted owing to the presence of blood bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7168ce29cbe058f7b4163e0f60e688b
https://doi.org/10.1016/j.colsurfb.2018.09.047
https://doi.org/10.1016/j.colsurfb.2018.09.047
Autor:
Sushant Lakkadwala, Jagdish Singh
Publikováno v:
Journal of Pharmaceutical Sciences. 107:2902-2913
Drug delivery to the brain has been a major challenge due to the presence of the blood-brain barrier, which limits the uptake of most chemotherapeutics into brain. We developed a dual-functionalized liposomal delivery system, conjugating cell penetra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7082e49142109b47472ea1266fcbf9c
https://doi.org/10.1016/j.xphs.2018.07.020
https://doi.org/10.1016/j.xphs.2018.07.020
Publikováno v:
J Control Release
Glioblastoma is a hostile brain tumor associated with high infiltration leading to poor prognosis. Anti-cancer chemotherapeutic agents have limited access into the brain due to the presence of the blood brain barrier (BBB). In this study, we designed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b67ac7c69a66540d6f96402f079267b
https://pubmed.ncbi.nlm.nih.gov/31252036
https://pubmed.ncbi.nlm.nih.gov/31252036
Autor:
Yolanda Alvarado, Débora Fretes Argenta, Raquel de Melo Barbosa, Marta Bartel, Cyril Cadiou, Maité Callewaert, Thiago Caon, Françoise Chuburu, Michael K. Danquah, Manita Das, Alekha K. Dash, Eneida de Paula, Christine Lamenha Luna Finkler, M.A. Galán, Tapan Kumar Giri, A. González-Garcinuño, Paulina Głowala, Javier Illescas, Arun K. Iyer, Sougata Jana, Nilofer Jasmin, Beatriz Jurado-Sánchez, Soundarapandian Kannan, Sushil K. Kashaw, Pamela Krug, Marta Kwiatkowska, Sushant Lakkadwala, Sophie Laurent, Ya Li, Weijie Liang, Nan Liu, Yanan Liu, Volodymyr Malytskyi, Silvia Maria Martelli, E.M. Martín del Valle, Maciej Mazur, Igor Meerovich, Ilona Mojzych, Juliette Moreau, Claudia Muro, V. Nipun Babu, Marta Pacheco-Jerez, Chandrababu Rejeeth, Francisco Riera, Guillaume Rigaux, Bruna dos Santos Rodrigues, Prashant Sahu, Samaresh Sau, Kalyan Kumar Sen, Patrícia Severino, Divya Sharma, Jagdish Singh, Aleksandra Skiba, Archana Solanki, A. Tabernero, Kei X. Tan, Sonal I. Thakore, Safina Ujan, Raju Vivek, Agata Wójtowicz, Barbara Wysocka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d809d7edcf61e9f5f0e837e0a670941d
https://doi.org/10.1016/b978-0-12-818433-2.00022-4
https://doi.org/10.1016/b978-0-12-818433-2.00022-4
Autor:
Divya Sharma, Sushant Lakkadwala, Bruna dos Santos Rodrigues, Jagdish Singh, Sanjay Arora, Amrita Banerjee
Publikováno v:
Functional Chitosan ISBN: 9789811502620
Conventional methods for gene delivery with non-viral or viral delivery carriers are beset with various disadvantages such as immune reactions, low transfection efficiency, and toxicity. Innumerable methods are under investigation to help improve the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b865927c90a879ef55510e678558002f
https://doi.org/10.1007/978-981-15-0263-7_8
https://doi.org/10.1007/978-981-15-0263-7_8
Publikováno v:
Nanomedicine
Combination therapy has emerged as an efficient way to deliver chemotherapeutics for treatment of glioblastoma. It provides collaborative approach of targeting cancer cells by acting via multiple mechanisms, thereby reducing drug resistance. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0804debcd888c50db636074fc343c28d
https://doi.org/10.1016/j.nano.2019.102112
https://doi.org/10.1016/j.nano.2019.102112
Publikováno v:
Polymers, Vol 7, Iss 8, Pp 1510-1521 (2015)
Polymers
Volume 7
Issue 8
Pages 1510-1521
Polymers; Volume 7; Issue 8; Pages: 1510-1521
Polymers
Volume 7
Issue 8
Pages 1510-1521
Polymers; Volume 7; Issue 8; Pages: 1510-1521
The purpose of this study was to investigate the effects of size and type of incorporated model molecules on the polymer degradation and release profile from thermosensitive triblock copolymer based controlled delivery systems. In vitro release of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5164ac09a231c7a2d9d2febf7644aa8c
https://doi.org/10.3390/polym7081467
https://doi.org/10.3390/polym7081467