Zobrazeno 1 - 10
of 243
pro vyhledávání: '"Suse Broyde"'
Autor:
Zhi Liu, Shuang Ding, Konstantin Kropachev, Lei Jia, Shantu Amin, Suse Broyde, Nicholas E Geacintov
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0142068 (2015)
Externí odkaz:
https://doaj.org/article/e53a026c4cb047678fc575fccf0baa1f
Autor:
Zhi Liu, Shuang Ding, Konstantin Kropachev, Lei Jia, Shantu Amin, Suse Broyde, Nicholas E Geacintov
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137124 (2015)
The nucleotide excision repair of certain bulky DNA lesions is abrogated in some specific non-canonical DNA base sequence contexts, while the removal of the same lesions by the nucleotide excision repair mechanism is efficient in duplexes in which al
Externí odkaz:
https://doaj.org/article/8d1675f19658422baf1b0b414fbd00b3
Publikováno v:
Journal of Nucleic Acids, Vol 2010 (2010)
Externí odkaz:
https://doaj.org/article/09dfcb6fe6d8435ab1a96ab7bebd610f
Publikováno v:
Journal of Nucleic Acids, Vol 2010 (2010)
Nucleotide excision repair (NER) plays a critical role in maintaining the integrity of the genome when damaged by bulky DNA lesions, since inefficient repair can cause mutations and human diseases notably cancer. The structural properties of DNA lesi
Externí odkaz:
https://doaj.org/article/4e507a035e2242c88be318da4b37bd75
Autor:
Olga Rechkoblit, Lucy Malinina, Yuan Cheng, Vitaly Kuryavyi, Suse Broyde, Nicholas E Geacintov, Dinshaw J Patel
Publikováno v:
PLoS Biology, Vol 4, Iss 1, p e11 (2006)
7,8-dihydro-8-oxoguanine (oxoG), the predominant lesion formed following oxidative damage of DNA by reactive oxygen species, is processed differently by replicative and bypass polymerases. Our kinetic primer extension studies demonstrate that the byp
Externí odkaz:
https://doaj.org/article/0fb18b0ddf2741d4beb478a569725a93
Publikováno v:
Nucleic Acids Research. 50:6837-6853
In nucleotide excision repair (NER), the xeroderma pigmentosum D helicase (XPD) scans DNA searching for bulky lesions, stalls when encountering such damage to verify its presence, and allows repair to proceed. Structural studies have shown XPD bound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badb3845e3ddcb1b1506d48f8e49c319
https://doi.org/10.1093/nar/gkac496
https://doi.org/10.1093/nar/gkac496
Autor:
Ana H, Sales, Vincent, Zheng, Maya A, Kenawy, Mark, Kakembo, Lu, Zhang, Vladimir, Shafirovich, Suse, Broyde, Nicholas E, Geacintov
Publikováno v:
International journal of molecular sciences. 23(24)
DNA helicase unwinding activity can be inhibited by small molecules and by covalently bound DNA lesions. Little is known about the relationships between the structural features of DNA lesions and their impact on unwinding rates and processivities. Em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::abab7553acf60e12e18ec05d4ce642d4
https://pubmed.ncbi.nlm.nih.gov/36555294
https://pubmed.ncbi.nlm.nih.gov/36555294
Autor:
Jung Hyun Min, Anjum Ansari, Jagannath Kuchlyan, Suse Broyde, Saroj Baral, Amirrasoul Tavakoli, Debamita Paul, Hong Mu
Publikováno v:
RSC Chemical Biology
Biomolecular structural changes upon binding/unbinding are key to their functions. However, characterization of such dynamical processes is difficult as it requires ways to rapidly and specifically trigger the assembly/disassembly as well as ways to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57ea70a3030fe199cbcadbe653c033c
http://europepmc.org/articles/PMC8142930
http://europepmc.org/articles/PMC8142930
Autor:
Suse Broyde, Debamita Paul, Sagnik Chakraborty, Qing Dai, Xuejing Chen, Amirrasoul Tavakoli, Hong Mu, Jung Hyun Min, Anjum Ansari, Chuan He
Publikováno v:
Nucleic Acids Research
XPC/Rad4 initiates eukaryotic nucleotide excision repair on structurally diverse helix-destabilizing/distorting DNA lesions by selectively ‘opening’ these sites while rapidly diffusing along undamaged DNA. Previous structural studies showed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1755e3a7102d2e27491b20e2c8e2625b
https://doi.org/10.1093/nar/gkaa909
https://doi.org/10.1093/nar/gkaa909
Autor:
Ana H. Sales, Vincent Zheng, Maya A. Kenawy, Mark Kakembo, Lu Zhang, Vladimir Shafirovich, Suse Broyde, Nicholas E. Geacintov
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 15654
DNA helicase unwinding activity can be inhibited by small molecules and by covalently bound DNA lesions. Little is known about the relationships between the structural features of DNA lesions and their impact on unwinding rates and processivities. Em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41a87bac868ce040b1768b0afae72d2
https://doi.org/10.3390/ijms232415654
https://doi.org/10.3390/ijms232415654