Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Susbin Raj Wagle"'
Autor:
Armin Mooranian, Jacqueline Chester, Edan Johnston, Corina Mihaela Ionescu, Daniel Walker, Melissa Jones, Susbin Raj Wagle, Bozica Kovacevic, Thomas Foster, Momir Mikov, Hani Al-Salami
Publikováno v:
Biomolecules, Vol 12, Iss 7, p 877 (2022)
Recent preclinical studies in our laboratory have shown that the bile acid profile is altered during diabetes development and such alteration has been linked to the diabetes-associated inflammatory profile. Hence, this study aimed to investigate if t
Externí odkaz:
https://doaj.org/article/c2c2d55124b74b4b8101fd8263641d5c
Autor:
Bozica Kovacevic, Corina Mihaela Ionescu, Melissa Jones, Susbin Raj Wagle, Michael Lewkowicz, Maja Đanić, Momir Mikov, Armin Mooranian, Hani Al-Salami
Publikováno v:
Gels, Vol 8, Iss 6, p 358 (2022)
The pathophysiology of a multitude of diseases is influenced by bioenergetic dysfunction. Healthy mitochondria are presented as essential for the regulation and function of multiple cell types, including the cells of relevance for this research: panc
Externí odkaz:
https://doaj.org/article/4625368631034b6195009c55b636af99
Autor:
Armin Mooranian, Melissa Jones, Daniel Walker, Corina Mihaela Ionescu, Susbin Raj Wagle, Bozica Kovacevic, Jacqueline Chester, Thomas Foster, Edan Johnston, Jafri Kuthubutheen, Daniel Brown, Marcus D. Atlas, Momir Mikov, Hani Al-Salami
Publikováno v:
Nanomaterials, Vol 12, Iss 4, p 647 (2022)
Bile acids (BA)s are known surfactants and well-documented to play a major role in food digestion and absorption. Recently, potential endocrinological and formulation-stabilisation effects of BAs have been explored and their pharmacological effects o
Externí odkaz:
https://doaj.org/article/a345f24a9c93499ebc4322aacdde9a68
Autor:
Armin Mooranian, Corina Mihaela Ionescu, Susbin Raj Wagle, Bozica Kovacevic, Daniel Walker, Melissa Jones, Jacqueline Chester, Thomas Foster, Edan Johnston, Sanja Kojic, Goran Stojanovic, Momir Mikov, Hani Al-Salami
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 111 (2022)
A recent study showed an association between diabetes development and the bile acid lithocholic acid (LCA), while another study demonstrated positive biological effects of the conjugated bile acid, taurocholic acid (TCA), on pancreatic cells. Thus, t
Externí odkaz:
https://doaj.org/article/6e70703d17bd4e97bf1f7e3075cc6d55
Autor:
Armin Mooranian, Corina Mihaela Ionescu, Daniel Walker, Melissa Jones, Susbin Raj Wagle, Bozica Kovacevic, Jacqueline Chester, Thomas Foster, Edan Johnston, Jafri Kuthubutheen, Daniel Brown, Marcus D. Atlas, Momir Mikov, Hani Al-Salami
Publikováno v:
Biomolecules, Vol 12, Iss 1, p 73 (2022)
Recent studies in our laboratories have shown promising effects of bile acids in ➀ drug encapsulation for oral targeted delivery (via capsule stabilization) particularly when encapsulated with Eudragit NM30D® and ➁ viable-cell encapsulation and
Externí odkaz:
https://doaj.org/article/729f3ec7baed47fb98fe1400c7898c51
Autor:
Armin Mooranian, Melissa Jones, Corina Mihaela Ionescu, Daniel Walker, Susbin Raj Wagle, Bozica Kovacevic, Jacqueline Chester, Thomas Foster, Edan Johnston, Jafri Kuthubutheen, Daniel Brown, Momir Mikov, Hani Al-Salami
Publikováno v:
Journal of Functional Biomaterials, Vol 12, Iss 4, p 68 (2021)
Pancreatic β-cell loss and failure with subsequent deficiency of insulin production is the hallmark of type 1 diabetes (T1D) and late-stage type 2 diabetes (T2D). Despite the availability of parental insulin, serious complications of both types are
Externí odkaz:
https://doaj.org/article/4bf8056c3dae49d9b27fdb33ea79b8a2
Autor:
Armin Mooranian, Louise Carey, Corina Mihaela Ionescu, Daniel Walker, Melissa Jones, Susbin Raj Wagle, Bozica Kovacevic, Thomas Foster, Jacqueline Chester, Edan Johnston, Momir Mikov, Hani Al-Salami
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1667 (2021)
Introduction: Bile acid-based drug encapsulation for oral delivery has been recently explored in our laboratory and has shown to be beneficial in terms of drug-targeted delivery and release profile, but stability at various temperatures has not previ
Externí odkaz:
https://doaj.org/article/9734384b80a14ca9a3867de795c1234f
Autor:
Armin Mooranian, Corina Mihaela Ionescu, Susbin Raj Wagle, Bozica Kovacevic, Daniel Walker, Melissa Jones, Jacqueline Chester, Thomas Foster, Edan Johnston, Sanja Kojic, Goran Stojanovic, Momir Mikov, Hani Al-Salami
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1713 (2021)
Introduction. Several studies have shown that different biomaterials and hydrogels comprising various bile acids such as chenodeoxycholic acid (CDCA), as well as excipients such as poly-(styrene)-sulphonate (PSS) and poly-(allyl)-amine (PAA), exhibit
Externí odkaz:
https://doaj.org/article/0107377ee3ee49729065f82f7a5d577e
Autor:
Armin Mooranian, Corina Mihaela Ionescu, Susbin Raj Wagle, Bozica Kovacevic, Daniel Walker, Melissa Jones, Jacqueline Chester, Edan Johnston, Maja Danic, Momir Mikov, Crispin Dass, Hani Al-Salami
Publikováno v:
Cells, Vol 10, Iss 9, p 2437 (2021)
Introduction. Primary bile acids (PBAs) are produced and released into human gut as a result of cholesterol catabolism in the liver. A predominant PBA is chenodeoxycholic acid (CDCA), which in a recent study in our laboratory, showed significant exci
Externí odkaz:
https://doaj.org/article/b739788dae964d53b59149731f3721e2
Autor:
Susbin Raj Wagle, Bozica Kovacevic, Corina Mihaela Ionescu, Daniel Walker, Melissa Jones, Louise Carey, Ryusuke Takechi, Momir Mikov, Armin Mooranian, Hani Al-Salami
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1223 (2021)
Probucol (PB) is a highly lipophilic drug with potential protective effects on pancreatic β-cells from inflammation and oxidation. PB has poor bioavailability and solubility, and despite many attempts, significant improvement in antidiabetic effects
Externí odkaz:
https://doaj.org/article/965576ba32264499a84beb4640f971f9