Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Susantha, Gomis"'
Autor:
Hemlata Gautam, Noor Ahmad Shaik, Babajan Banaganapalli, Shelly Popowich, Iresha Subhasinghe, Lisanework E. Ayalew, Rupasri Mandal, David S. Wishart, Suresh Tikoo, Susantha Gomis
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background Necrotic enteritis (NE) is an economically important disease of broiler chickens caused by Clostridium perfringens (CP). The pathogenesis, or disease process, of NE is still not clear. This study aimed to identify the alterations
Externí odkaz:
https://doaj.org/article/9422609d5d524344b8b276d56bf9b18b
Autor:
Iresha Subhasinghe, Khawaja Ashfaque Ahmed, Lisanework E. Ayalew, Hemlata Gautam, Shelly Popowich, Ayumi Matsuyama-Kato, Betty Chow-Lockerbie, Suresh K. Tikoo, Philip Griebel, Susantha Gomis
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Oligodeoxynucleotides containing CpG motifs (CpG-ODN) can promote antimicrobial immunity in chickens by enriching immune compartments and activating immune cells. Innate memory, or trained immunity, has been demonstrated in humans and mice,
Externí odkaz:
https://doaj.org/article/afe11101d1254218a19debb706f0c963
Autor:
Iresha Subhasinghe, Ayumi Matsuyama-Kato, Khawaja Ashfaque Ahmed, Lisanework E. Ayalew, Hemlata Gautam, Shelly Popowich, Betty Chow-Lockerbie, Suresh K. Tikoo, Philip Griebel, Susantha Gomis
Publikováno v:
Poultry Science, Vol 103, Iss 10, Pp 104078- (2024)
ABSTRACT: In the past, we demonstrated that oligodeoxynucleotides containing CpG motifs (CpG-ODN) mimicking bacterial DNA, stimulate the innate immune system of neonatal broiler chickens and protect them against Escherichia coli and Salmonella Typhim
Externí odkaz:
https://doaj.org/article/b7212529aa0147d0bba2bc1e0bc1a1a3
Autor:
Hemlata Gautam, Lisanework E. Ayalew, Noor Ahmad Shaik, Iresha Subhasinghe, Shelly Popowich, Betty Chow-Lockerbie, Alexa Dixon, Khawaja Ashfaque Ahmed, Suresh K. Tikoo, Susantha Gomis
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Necrotic enteritis (NE) is a severe intestinal infection that affects both humans and poultry. It is caused by the bacterium Clostridium perfringens (CP), but the precise mechanisms underlying the disease pathogenesis remain elusi
Externí odkaz:
https://doaj.org/article/82d2cd565d104942a103028bdfdba042
Autor:
Lisanework E. Ayalew, Shelly Popowich, Betty Chow-Lockerbie, Hemlata Gautam, Iresha Subhasinghe, Khawaja Ashfaque Ahmed, Suresh K. Tikoo, Davor Ojkic, Susantha Gomis
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Variant avian reoviruses (ARVs) are economically important emerging pathogens of poultry, which mainly affect young broiler chickens and cause significant production losses. Currently, there are no effective commercial vaccines available for control
Externí odkaz:
https://doaj.org/article/d4c23f0d5d004e58a8f7ac584943174a
Autor:
Ruwani Karunarathna, Khawaja Ashfaque Ahmed, Kalhari Goonewardene, Thushari Gunawardana, Shanika Kurukulasuriya, Mengying Liu, Ashish Gupta, Shelly Popowich, Lisanework Ayalew, Betty Chow- Lockerbie, Philip Willson, Musangu Ngeleka, Susantha Gomis
Publikováno v:
Poultry Science, Vol 101, Iss 8, Pp 101983- (2022)
Enterococci and Escherichia coli are opportunistic pathogens of poultry and are associated with embryo and neonatal chick mortality. We have recently demonstrated that 56% of dead broiler chicken embryos in commercial hatcheries in western Canada wer
Externí odkaz:
https://doaj.org/article/e022eda1980e4d6694fd39d7e79ec4be
Autor:
Kalhari Bandara Goonewardene, Naama Karu, Khawaja Ashfaque Ahmed, Shelly Popowich, Betty Chow-Lockerbie, Lisanework E. Ayalew, Ruwani Karunarathna, Thushari Gunawardana, Mengying Liu, Suresh K. Tikoo, Marianna Foldvari, Philip Willson, Rupasri Mandal, David S. Wishart, Susantha Gomis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Synthetic CpG-ODNs can promote antimicrobial immunity in neonatal chicks by enriching immune compartments and activating immune cells. Activated immune cells undergo profound metabolic changes to meet cellular biosynthesis and energy demands
Externí odkaz:
https://doaj.org/article/01719c93fa794b979262ca838bb4f452
Autor:
Dinesh H. Wellawa, Po-King S. Lam, Aaron P. White, Susantha Gomis, Brenda Allan, Wolfgang Köster
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The roles of TonB mediated Fe3+ (ferric iron) uptake via enterobactin (involving biosynthesis genes entABCDEF) and Fe2+ (ferrous iron) uptake through the FeoABC transporter are poorly defined in the context of chicken-Salmonella interactions. Both up
Externí odkaz:
https://doaj.org/article/984d637975d1488fbf398091ded0f4ca
Autor:
Lisanework E. Ayalew, Khawaja Ashfaque Ahmed, Shelly Popowich, Betty-Chow Lockerbie, Ashish Gupta, Suresh K. Tikoo, Davor Ojkic, Susantha Gomis
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Newly emerging arthrotropic avian reoviruses (ARVs) are genetically divergent, antigenically heterogeneous, and economically costly. Nevertheless, the mechanism of emerging ARV-induced disease pathogenesis and potential differences in virulence betwe
Externí odkaz:
https://doaj.org/article/0476410d13b24d64aadbf87db4fe1ec1
Autor:
Thushari Gunawardana, Khawaja Ashfaque Ahmed, Kalhari Goonewardene, Shelly Popowich, Shanika Kurukulasuriya, Ruwani Karunarathana, Lisanework E. Ayalew, Ashish Gupta, Betty Lockerbie, Marianna Foldvari, Suresh K. Tikoo, Philip Willson, Susantha Gomis
Publikováno v:
Journal of Immunology Research, Vol 2020 (2020)
Immunoprotective function of oligodeoxynucleotides containing CpG motifs (CpG-ODN) has been demonstrated in neonatal chickens against common bacterial pathogens such as E.coli and Salmonella sp. Our recent study reported that CpG-ODN administration e
Externí odkaz:
https://doaj.org/article/ba26294fc7074895b52c52eefc0e0555