Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Susanne tom-Dieck"'
Autor:
Patricia Kreis, Christian Gallrein, Eugenia Rojas-Puente, Till G. A. Mack, Cristina Kroon, Viktor Dinkel, Claudia Willmes, Kai Murk, Susanne tom-Dieck, Erin M. Schuman, Janine Kirstein, Britta J. Eickholt
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Drebrin is an actin-binding protein known to play a role in neuronal dendritic spines but its precise regulation is unclear. Here, the authors report that DBN is activated by oxidative stress in an ATM-kinase dependent manner and increases resistance
Externí odkaz:
https://doaj.org/article/8f4a9676b36d4e899073e6805e0d669d
Autor:
Alexia Martínez de Paz, Leila Khajavi, Hélène Martin, Rafael Claveria-Gimeno, Susanne Tom Dieck, Manjinder S. Cheema, Jose V. Sanchez-Mut, Malgorzata M. Moksa, Annaick Carles, Nick I. Brodie, Taimoor I. Sheikh, Melissa E. Freeman, Evgeniy V. Petrotchenko, Christoph H. Borchers, Erin M. Schuman, Matthias Zytnicki, Adrian Velazquez-Campoy, Olga Abian, Martin Hirst, Manel Esteller, John B. Vincent, Cécile E. Malnou, Juan Ausió
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-16 (2019)
Abstract Background MeCP2—a chromatin-binding protein associated with Rett syndrome—has two main isoforms, MeCP2-E1 and MeCP2-E2, differing in a few N-terminal amino acid residues. Previous studies have shown brain region-specific expression of t
Externí odkaz:
https://doaj.org/article/77c2d4837dd042b6b9fd1383b11eace4
Autor:
Julio D Perez, Susanne tom Dieck, Beatriz Alvarez-Castelao, Georgi Tushev, Ivy CW Chan, Erin M Schuman
Publikováno v:
eLife, Vol 10 (2021)
Although mRNAs are localized in the processes of excitatory neurons, it is still unclear whether interneurons also localize a large population of mRNAs. In addition, the variability in the localized mRNA population within and between cell types is un
Externí odkaz:
https://doaj.org/article/c8d374d1a10a462a9c65dc2cb6f905c6
Autor:
Beatriz Alvarez-Castelao, Susanne tom Dieck, Claudia M Fusco, Paul Donlin-Asp, Julio D Perez, Erin M Schuman
Publikováno v:
eLife, Vol 9 (2020)
We examined the feedback between the major protein degradation pathway, the ubiquitin-proteasome system (UPS), and protein synthesis in rat and mouse neurons. When protein degradation was inhibited, we observed a coordinate dramatic reduction in nasc
Externí odkaz:
https://doaj.org/article/a2a91b9d6fb5494ea948d96533c2e08d
Autor:
Cyril Hanus, Lisa Kochen, Susanne tom Dieck, Victor Racine, Jean-Baptiste Sibarita, Erin M. Schuman, Michael D. Ehlers
Publikováno v:
Cell Reports, Vol 7, Iss 6, Pp 1771-1778 (2014)
Localized signaling in neuronal dendrites requires tight spatial control of membrane composition. Upon initial synthesis, nascent secretory cargo in dendrites exits the endoplasmic reticulum (ER) from local zones of ER complexity that are spatially c
Externí odkaz:
https://doaj.org/article/2d431758981d4e6b96da3be4ab721282
Autor:
Allison Kao, Ina Bartnik, Susanne tom Dieck, Belquis Nassim-Assir, Erin M. Schuman, Georgi Tushev, Caspar Glock, Anne Biever
Publikováno v:
Proceedings of the National Academy of Sciences (PNAS)
Proceedings of the National Academy of Sciences of the United States of America
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America
Proc Natl Acad Sci U S A
Significance Proteins are the key drivers of neuronal synaptic function. The regulation of gene expression is important for the formation and modification of synapses throughout the lifespan. The complexity of dendrites and axons imposes unique chall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04eaf26849ce88d4c516116b6c6bd5b5
https://doi.org/10.1073/pnas.2113929118
https://doi.org/10.1073/pnas.2113929118
Autor:
Viktor Dinkel, Janine Kirstein, Cristina Kroon, Christian Gallrein, Eugenia Rojas-Puente, Till G. A. Mack, Erin M. Schuman, Kai Murk, Susanne tom-Dieck, Claudia G Willmes, Britta J. Eickholt, Patricia Kreis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nat Commun
Nature Communications
Nat Commun
Nature Communications
Drebrin (DBN) regulates cytoskeletal functions during neuronal development, and is thought to contribute to structural and functional synaptic changes associated with aging and Alzheimer’s disease. Here we show that DBN coordinates stress signallin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d4c540e556cccb22fd2fcdcf1bb0ea
http://link.springer.com/article/10.1038/s41467-019-08420-w
http://link.springer.com/article/10.1038/s41467-019-08420-w
Autor:
Erin M. Schuman, Ivy C. W. Chan, Julio D Perez, Beatriz Alvarez-Castelao, Susanne tom Dieck, Georgi Tushev
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Although mRNAs are localized in the processes of excitatory neurons, it is still unclear whether interneurons also localize a large population of mRNAs. In addition, the variability in the localized mRNA population within and between cell types is un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc49f04f85555e62cfab31033ce78c19
https://doi.org/10.7554/elife.63092
https://doi.org/10.7554/elife.63092
Autor:
Jan S. Schuhmacher, Susanne tom Dieck, Savvas Christoforidis, Cedric Landerer, Lena Hersemann, Sarah Seifert, Angelika Giner, Agnes Toth-Petroczy, Yannis Kalaidzidis, Erin M. Schuman, Marino Zerial
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83d9d5b2a22c2089c6a97fafc5dc2dc5
https://doi.org/10.2139/ssrn.3877557
https://doi.org/10.2139/ssrn.3877557
