Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Susanne Zach"'
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102164- (2023)
Summary: Developing an in vitro platform to study neuron-oligodendrocyte interaction, particularly myelination, is essential to understand aberrant myelination in neuropsychiatric and neurodegenerative diseases. Here, we provide a controlled, direct
Externí odkaz:
https://doaj.org/article/33bd391e07d74d919dd6f5534637babb
Autor:
Mareike Caesar, Susanne Zach, Coby B. Carlson, Kathrin Brockmann, Thomas Gasser, Frank Gillardon
Publikováno v:
Neurobiology of Disease, Vol 54, Iss , Pp 280-288 (2013)
Recent studies indicate that the Parkinson's disease-linked leucine-rich repeat kinase 2 (LRRK2) modulates cytoskeletal functions by regulating actin and tubulin dynamics, thereby affecting neurite outgrowth. By interactome analysis we demonstrate th
Externí odkaz:
https://doaj.org/article/14cfffd8019d460fb9bef29499ea864d
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13191 (2010)
Dominant mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's disease, however, the underlying pathogenic mechanisms are poorly understood. Several in vitro studies have shown that the most frequent mutat
Externí odkaz:
https://doaj.org/article/799fe091c90d4d0e94353d49dea3ed6b
Autor:
German Preciat, Agnieszka B. Wegrzyn, Edinson Lucumi Moreno, Cornelius C.W. Willacey, Jennifer Modamio, Fatima L. Monteiro, Diana El Assal, Alissa Schurink, Miguel A.P. Oliveira, Zhi Zhang, Ben Cousins, Hulda S. Haraldsdóttir, Siham Hachi, Susanne Zach, German Leparc, Yin Tat Lee, Bastian Hengerer, Santosh Vempala, Michael A. Saunders, Amy Harms, Enrico Glaab, Jens C. Schwamborn, Ines Thiele, Thomas Hankemeier, Ronan M.T. Fleming
Patient-derived cellular models are a powerful approach to study human disease, especially neurode-generative diseases, such as Parkinson’s disease, where affected primary neurons, e.g., substantia nigra dopaminergic neurons, are almost inaccessibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bcc67eaf5b3fd1d397e56bcd6b6b301
https://doi.org/10.1101/2021.06.30.450562
https://doi.org/10.1101/2021.06.30.450562
Autor:
Susanne Zach, Sandra Felk, Mareike Caesar, Frank Gillardon, Gunnar Bronstad, Jan O. Aasly, Thomas Gasser
Publikováno v:
Glia. 62:1075-1092
Increasing evidence suggests that Parkinson's disease (PD)-linked Leucine-rich repeat kinase 2 (LRRK2) has a role in peripheral and brain-resident immune cells. Furthermore, dysregulation of the anti-inflammatory, neurotrophic protein progranulin (PG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bae61a87a0afead91f6d6dc71b785971
https://doi.org/10.1002/glia.22663
https://doi.org/10.1002/glia.22663
Autor:
Tim H. Sparks, Katarzyna Jatczak, Kerstin Alm-Kübler, Yannick Curnel, Andreja Sušnik, Agrita Briede, Helfried Scheifinger, Anto Aasa, Øyvind Nordli, Josep Peñuelas, Susanne Zach, Yolanda Filella, Arnold J. H. van Vliet, Martin Striz, Pentti Pirinen, Annette Menzel, Elisabeth Koch, Alison Donnelly, Claudio Defila, Zalika Črepinšek, Viera Remisová, Rein Ahas, Åslög Dahl, Finn Måge, Nicole Estrella, Frank-M. Chmielewski, Peter Bissolli, Ol 'ga Braslavská, Ana Zust, Antonio Mestre, F. E. Wielgolaski
Publikováno v:
Global Change Biology. 12:1969-1976
Global climate change impacts can already be tracked in many physical and biological systems; in particular, terrestrial ecosystems provide a consistent picture of observed changes. One of the preferred indicators is phenology, the science of natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c94ba6d7e5879b3cc03efffc448e4b0
https://doi.org/10.1111/j.1365-2486.2006.01193.x
https://doi.org/10.1111/j.1365-2486.2006.01193.x
Autor:
Mareike, Caesar, Sandra, Felk, Susanne, Zach, Gunnar, Brønstad, Jan O, Aasly, Thomas, Gasser, Frank, Gillardon
Publikováno v:
Glia. 62(7)
Increasing evidence suggests that Parkinson's disease (PD)-linked Leucine-rich repeat kinase 2 (LRRK2) has a role in peripheral and brain-resident immune cells. Furthermore, dysregulation of the anti-inflammatory, neurotrophic protein progranulin (PG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e522946729c37b2eaaa0e3a373564ba
https://pubmed.ncbi.nlm.nih.gov/24652679
https://pubmed.ncbi.nlm.nih.gov/24652679
Autor:
Kathrin Brockmann, Mareike Caesar, Thomas Gasser, Susanne Zach, Coby B. Carlson, Frank Gillardon
Publikováno v:
Neurobiology of Disease, Vol 54, Iss, Pp 280-288 (2013)
Recent studies indicate that the Parkinson's disease-linked leucine-rich repeat kinase 2 (LRRK2) modulates cytoskeletal functions by regulating actin and tubulin dynamics, thereby affecting neurite outgrowth. By interactome analysis we demonstrate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91595b44a97e0536d17c338d74ddbbf1
https://pubmed.ncbi.nlm.nih.gov/23318930
https://pubmed.ncbi.nlm.nih.gov/23318930
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13191 (2010)
PLoS ONE
PLoS ONE
Background Dominant mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's disease, however, the underlying pathogenic mechanisms are poorly understood. Several in vitro studies have shown that the most fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f50c66c13aad28dadc3bec6b99b002d
http://europepmc.org/articles/PMC2951910?pdf=render
http://europepmc.org/articles/PMC2951910?pdf=render
Autor:
Friedrich Lottspeich, Ingo Ohlenschläger, Nathalie Wacht, Nikolaus Bresgen, Paolo Arosio, Bettina Dunkelmann, Elisabeth Kuffner, Peter Eckl, Brigitte Fiedler, Susanne Zach
Previously we have demonstrated an apoptosis inducing activity for a rat hepatocyte conditioned medium (CM) presumably mediated by acidic isoferritins. Here, we present support for this assumption since isoferritins purified from different rat hepato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991fb0c84b52dbc32d5e706188029066
http://hdl.handle.net/11379/21426
http://hdl.handle.net/11379/21426