Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Susanne Witt"'
Autor:
Julia Reichelt, Wiebke Sachs, Sarah Frömbling, Julia Fehlert, Maja Studencka-Turski, Anna Betz, Desiree Loreth, Lukas Blume, Susanne Witt, Sandra Pohl, Johannes Brand, Maire Czesla, Jan Knop, Bogdan I. Florea, Stephanie Zielinski, Marlies Sachs, Elion Hoxha, Irm Hermans-Borgmeyer, Gunther Zahner, Thorsten Wiech, Elke Krüger, Catherine Meyer-Schwesinger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Little is known about the mechanistic significance of the ubiquitin proteasome system (UPS) in a kidney autoimmune environment. In membranous nephropathy (MN), autoantibodies target podocytes of the glomerular filter resulting in proteinuria
Externí odkaz:
https://doaj.org/article/cee0c8ae32e746e8ba523351dc7de044
Autor:
Nico Brkovic, Nikolas Ohl, Ronald Maitschke-Rajasekharan, Susanne Witt, Irene Fernandez-Cuesta, Enrico Patrono, Alessandra Picchiotti
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S168-S169 (2023)
Externí odkaz:
https://doaj.org/article/fdde0f78fe1542e1821eea0020ff9076
Autor:
Tania Szal, Shweta Singh Chauhan, Philipp Lewe, Fatima-Zahra Rachad, Marina Madre, Laura Paunina, Susanne Witt, Ramakrishnan Parthasarathi, Björn Windshügel
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 1000 (2023)
Efflux pumps are a relevant factor in antimicrobial resistance. In E. coli, the tripartite efflux pump AcrAB-TolC removes a chemically diverse set of antibiotics from the bacterium. Therefore, small molecules interfering with efflux pump function are
Externí odkaz:
https://doaj.org/article/b61ee0133e1e4f9d85b6ebd6a4171f79
Autor:
Stephan Niebling, Katharina Veith, Benjamin Vollmer, Javier Lizarrondo, Osvaldo Burastero, Janina Schiller, Angelica Struve García, Philipp Lewe, Carolin Seuring, Susanne Witt, María García-Alai
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Successful sample preparation is the foundation to any structural biology technique. Membrane proteins are of particular interest as these are important targets for drug design, but also notoriously difficult to work with. For electron cryo-microscop
Externí odkaz:
https://doaj.org/article/b0f17dbc4aac4036962350cb153663d5
Autor:
Julia Reichelt, Wiebke Sachs, Sarah Frömbling, Julia Fehlert, Maja Studencka-Turski, Anna Betz, Desiree Loreth, Lukas Blume, Susanne Witt, Sandra Pohl, Johannes Brand, Maire Czesla, Jan Knop, Bogdan I. Florea, Stephanie Zielinski, Marlies Sachs, Elion Hoxha, Irm Hermans-Borgmeyer, Gunther Zahner, Thorsten Wiech, Elke Krüger, Catherine Meyer-Schwesinger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/2ddf8a9a90b44a33b9442749e01f62a3
Autor:
Jessica Rauch, Jessica Barton, Marcel Kwiatkowski, Malte Wunderlich, Pascal Steffen, Kristin Moderzynski, Stefanie Papp, Katharina Höhn, Hella Schwanke, Susanne Witt, Ulricke Richardt, Ute Mehlhoop, Hartmut Schlüter, Verena Pianka, Bernhard Fleischer, Dennis Tappe, Anke Osterloh
Publikováno v:
PLoS ONE, Vol 16, Iss 6 (2021)
Rickettsioses are neglected and emerging potentially fatal febrile diseases that are caused by obligate intracellular bacteria, rickettsiae. Rickettsia (R.) typhi and R. prowazekii constitute the typhus group (TG) of rickettsiae and are the causative
Externí odkaz:
https://doaj.org/article/6ec89ed4fdab4f60a4dd6fbb67fd2814
Autor:
Nahla Galal Metwally, Ann-Kathrin Tilly, Pedro Lubiana, Lisa K. Roth, Michael Dörpinghaus, Stephan Lorenzen, Kathrin Schuldt, Susanne Witt, Anna Bachmann, Henning Tidow, Thomas Gutsmann, Thorsten Burmester, Thomas Roeder, Egbert Tannich, Iris Bruchhaus
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract The ability of the parasite Plasmodium falciparum to evade the immune system and be sequestered within human small blood vessels is responsible for severe forms of malaria. The sequestration depends on the interaction between human endotheli
Externí odkaz:
https://doaj.org/article/42d13ef73daf4ff6bfba0bf2fa7c2781
Autor:
J. Stephan Wichers, Judith A. M. Scholz, Jan Strauss, Susanne Witt, Andrés Lill, Laura-Isabell Ehnold, Niklas Neupert, Benjamin Liffner, Renke Lühken, Michaela Petter, Stephan Lorenzen, Danny W. Wilson, Christian Löw, Catherine Lavazec, Iris Bruchhaus, Egbert Tannich, Tim W. Gilberger, Anna Bachmann
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT During its intraerythrocytic development, the malaria parasite Plasmodium falciparum exposes variant surface antigens (VSAs) on infected erythrocytes to establish and maintain an infection. One family of small VSAs is the polymorphic STEVOR
Externí odkaz:
https://doaj.org/article/517410248da74ba7892762b5ae7fb344
Autor:
Matthew Burrell, Simon J Henderson, Anna Ravnefjord, Fritz Schweikart, Susan B Fowler, Susanne Witt, Kenny M Hansson, Carl I Webster
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158114 (2016)
Neprilysin (NEP) is an endogenous protease that degrades a wide range of peptides including amyloid beta (Aβ), the main pathological component of Alzheimer's disease (AD). We have engineered NEP as a potential therapeutic for AD but found in pre-cli
Externí odkaz:
https://doaj.org/article/e66447b42ce24666aee4005e9eeeb96b
Autor:
Igor V. Bodrenko, Tsedenia Alemu Zewdie, Jiajun Wang, Eshita Paul, Susanne Witt, Mathias Winterhalter
Publikováno v:
Biochimie. 205:102-109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::666162214e0237bf63bae6aac3269f0f
https://doi.org/10.1016/j.biochi.2023.01.004
https://doi.org/10.1016/j.biochi.2023.01.004