Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Susanne V. Fleig"'
Autor:
Susanne V. Fleig, Franz F. Konen, Christoph Schröder, Jessica Schmitz, Stefan Gingele, Jan H. Bräsen, Svjetlana Lovric, Bernhard M. W. Schmidt, Hermann Haller, Thomas Skripuletz, Sibylle vonVietinghoff
Publikováno v:
Immunity, Inflammation and Disease, Vol 9, Iss 4, Pp 1479-1488 (2021)
Abstract Background Chronic kidney disease (CKD) is a common condition that increases mortality and the risk of cardiovascular and other morbidities regardless of underlying renal condition. Chronic inflammation promotes renal fibrosis. Recently, ren
Externí odkaz:
https://doaj.org/article/04b168f3baf14dcbb637959db0b05326
Autor:
Anne M. Hüsing, Vera C. Wulfmeyer, Svenja Gaedcke, Susanne V. Fleig, Song Rong, David DeLuca, Hermann Haller, Roland Schmitt, Sibylle von Vietinghoff
Publikováno v:
Journal of the American Society of Nephrology. 33:1487-1500
The risk of cardiovascular events rises after AKI. Leukocytes promote atherosclerotic plaque growth and instability. We established a model of enhanced remote atherosclerosis after renal ischemia-reperfusion (IR) injury and investigated the underlyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb6c98e8cb638476a64c5a29ae153db
https://doi.org/10.1681/asn.2022010048
https://doi.org/10.1681/asn.2022010048
Autor:
Adrian Goldspink, Jessica Schmitz, Olena Babyak, Nicolas Brauns, Julia Milleck, Anne M. Breloh, Susanne V. Fleig, Katarzyna Jobin, Lisa Schwarz, Hermann Haller, Florian Wagenlehner, Jan Hinrich Bräsen, Christian Kurts, Sibylle von Vietinghoff
Publikováno v:
Kidney International.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6d5ef07ccd35d9452567b7a1097a19a
https://doi.org/10.1016/j.kint.2023.03.034
https://doi.org/10.1016/j.kint.2023.03.034
Publikováno v:
Der Nephrologe. 17:3-10
Ernahrung spielt seit jeher eine bedeutende Rolle im Management chronischer Nierenerkrankungen (CKD). Allerdings wird das Outcome bei CKD, wie die Mortalitat, nicht nur vom fortschreitenden Verlust der Nierenfunktion, sondern mindestens ebenso stark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f04ea1b521a1f6cfc955925cd807148b
https://doi.org/10.1007/s11560-021-00539-6
https://doi.org/10.1007/s11560-021-00539-6
Autor:
Benjamin D. Humphreys, Flavia Gomes Machado, Benjamin L. Ebert, Susanne V. Fleig, Rebekka K. Schneider, Joel M. Henderson, Rafael Kramann, Derek P. DiRocco, Philip A. Bondzie
Publikováno v:
Cell Stem Cell. 16(1):51-66
Mesenchymal stem cells (MSCs) reside in the perivascular niche of many organs, including kidney, lung, liver, and heart, although their roles in these tissues are poorly understood. Here, we demonstrate that Gli1 marks perivascular MSC-like cells tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b6cc1ebe82635b921a06193f908442
Autor:
Dianne B. McKay, Benjamin D. Humphreys, Sanjeev Noel, Michael Heung, Paul W. Sanders, Joseph C. Gigliotti, Maria N. Martina-Lingua, Sashi G. Kasimsetty, Lakhmir S. Chawla, Kathleen D. Liu, S. Noel, Antoine G. Schneider, Can Ince, Zheng Dong, Peter A. McCullough, Timothy Ball, Raghavan Murugan, Hamid Rabb, Zoltan H. Endre, Etienne Macedo, Isaah S. Vincent, Liyu He, Stuart L. Goldstein, Didier Portilla, Rosalinde Masereeuw, Emaad M. Abdel-Rahman, Peter Pickkers, Daniel A. Peterson, A.R.A. Hamad, Nattachai Srisawat, Monica Zanella, Andrew D. Shaw, Hyun-Joon Shin, Kelly K. Andringa, Satz Mengensatzproduktion, Francesco Garzotto, Susanne V. Fleig, Samatha Bandapalle, Anupam Agarwal, Prasad Devarajan, Aashish Sharma, Esther Peters, Jennifer L. Pluznick, Sean M. Bagshaw, Volker Vallon, Mark D. Okusa, Claudio Ronco, Druckerei Stückle, Richard A. Zager, Man J. Livingston, Sean E. DeWolf, Ravindra L. Mehta, H. Rabb, John A. Kellum, Abdel Rahim A. Hamad, Mélanie Godin, Alana A. Shigeoka, Joseph V. Bonventre, Aneley Hundae, Marìa Jimena Mucino, Patrick T. Murray, Samir M. Parikh, Prabhleen Singh, Noureddin Nourbakhsh, S. Bandapalle, Mei Tran, Frederic T. Billings, M.N. Martina, Ali C.M. Johnson
Publikováno v:
Nephron Clinical Practice. 127:I-IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70824201965e2ed120e960f859e035c0
https://doi.org/10.1159/000367960
https://doi.org/10.1159/000367960
Autor:
Andreas Hofmeister, Jing Liu, Andrew P. McMahon, Ivica Grgic, Benjamin D. Humphreys, Jeremy S. Duffield, A. Michaela Krautzberger, Derek P. DiRocco, Susanne V. Fleig, Matthew A. Lalli, Bruce J. Aronow
Publikováno v:
Journal of the American Society of Nephrology. 25:1979-1990
Myofibroblasts secrete matrix during chronic injury, and their ablation ameliorates fibrosis. Development of new biomarkers and therapies for CKD will be aided by a detailed analysis of myofibroblast gene expression during the early stages of fibrosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7308c0a7698bbfd8fe212e6f0979ebee
https://doi.org/10.1681/asn.2013101143
https://doi.org/10.1681/asn.2013101143
Autor:
Susanne V Fleig, Kevin Brown, Hua Mao, Jason K. Sicklick, Ying Wang, Liu Yang, Anna Mae Diehl, Alessia Omenetti, Yin-Xiong Li
Publikováno v:
Journal of Hepatology. 48:98-106
Background/Aims Factors released during liver injury, such as platelet derived growth factor-BB (PDGF), promote accumulation of myofibroblastic hepatic stellate cells (MFB) that drive the pathogenesis of cirrhosis. The hedgehog (Hh) pathway regulates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187a4f87f1818c8c5c56bcb13b7496f0
https://doi.org/10.1016/j.jhep.2007.07.032
https://doi.org/10.1016/j.jhep.2007.07.032
Autor:
Hendrika M.A. VanDongen, Susanne V Fleig, Liu Yang, Anna Mae Diehl, Steve S. Choi, Jiawen Huang, Jason K. Sicklick, Alessia Omenetti, Youngmi Jung
Publikováno v:
Laboratory Investigation. 87:1227-1239
Progenitors regenerate fatty livers but the mechanisms involved are uncertain. The Hedgehog pathway regulates mesendodermal progenitors and modulates mesenchymal-epithelial interactions during tissue remodeling. To determine if Hedgehog signaling inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab31ff13083239ebaa43886cb19b5f49
https://doi.org/10.1038/labinvest.3700689
https://doi.org/10.1038/labinvest.3700689
Publikováno v:
Nephron. Clinical practice. 127(1-4)
Hundreds of clinical trials are currently investigating the potential for mesenchymal stem cells (MSC) to treat human disease, including kidney disease. There is tremendous excitement over the therapeutic potential of this form of stem cell therapy a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6073f682c4c982bb124978be86e27d0
https://pubmed.ncbi.nlm.nih.gov/25343826
https://pubmed.ncbi.nlm.nih.gov/25343826