Screening of complex fucoidans from four brown algae species as procoagulant agents

Autor: Catherine Quinn, Sabine Knappe, Zhenqing Zhang, Christina M. Szabo, Friedrich Scheiflinger, James Catarello, Susanne Till, G. Joseph Ray, Michael Dockal

Publikováno v: Carbohydrate Polymers. 115:677-685

Fucoidans are complex sulfated polysaccharides extracted from brown algae. Depending on the concentration, they have been shown to stimulate and inhibit blood coagulation in vitro. Promotion of coagulation is mediated by blocking tissue factor pathwa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06f287d0e870e05de92c23761349aac
https://doi.org/10.1016/j.carbpol.2014.09.001

The Application of Thrombin Generation Test Is Compromised By Antithrombin III Deficiency

Autor: Michael Dockal, Friedrich Scheiflinger, Susanne Till, Sabine Knappe, Gabriele Gerstenbauer

Publikováno v: Blood. 126:4663-4663

Background: Antithrombin III (ATIII) is a stoichiometric inhibitor of factor Xa and thrombin and a major physiological regulator of coagulation. Reduction of ATIII levels, for example in patients with congenital ATIII deficiency, causes a rise in act

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ddb84fda7d81ce6e9801f968bf66576
https://doi.org/10.1182/blood.v126.23.4663.4663

Combining affinity purification by ADP-ribose-binding macro domains with mass spectrometry to define the mammalian ADP-ribosyl proteome

Autor: Antonio Mario Tamburro, Daniela Corda, Nadia Dani, Annalisa Stilla, Adriano Marchegiani, Susanne Till, Andreas G. Ladurner, Maria Di Girolamo

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America 106 (2009): 4243–4248. doi:10.1073/pnas.0900066106
info:cnr-pdr/source/autori:Dani N.; Stilla A.; Marchegiani A.; Tamburro A.; Till S.; Ladurner A.G.; Corda D.; Di Girolamo M./titolo:Combining affinity purification by ADP-ribose-binding macro domains with mass spectrometry to define the mammalian ADP-ribosyl proteome/doi:10.1073%2Fpnas.0900066106/rivista:Proceedings of the National Academy of Sciences of the United States of America/anno:2009/pagina_da:4243/pagina_a:4248/intervallo_pagine:4243–4248/volume:106

Mono-ADP-ribosylation is a reversible posttranslational modification that modulates the function of target proteins. The enzymes that catalyze this reaction in mammalian cells are either bacterial pathogenic toxins or endogenous cellular ADP-ribosylt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0427f117b3ad524fc7734462fe8ecc5
http://www.cnr.it/prodotto/i/9160

RNA Pol IV plays catch with Argonaute 4

Autor: Susanne Till, Andreas G. Ladurner

Publikováno v: Cell. 131(4)

Small-interfering RNAs regulate gene expression by affecting chromatin structure, transcription, translation, and RNA stability. In a recent report in Genes & Development, El-Shami et al. (2007) show that in plants, Argonaute 4—which is involved in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4240f641c0bb726c9743f06c326f2fa6
https://pubmed.ncbi.nlm.nih.gov/18022355

PARP: a transferase by any other name

Autor: Susanne Till, Konstantina Diamantara, Andreas G. Ladurner

Publikováno v: Nature Structural & Molecular Biology. 15:1243-1244

A recent report shows that several 'poly-ADP-ribose-polymerases' may function exclusively as a family of endogenous mono-ADP-ribosyltransferases, providing a new, molecularly less complex and broadened cellular role for this elusive post-translationa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::69933f97ecba31861d57a671ad3985bb
https://doi.org/10.1038/nsmb1208-1243