Zobrazeno 1 - 10 of 41 pro vyhledávání: '"Susanne Syberg"'
1
Akademický článek
Genetic Background Strongly Influences the Bone Phenotype of P2X7 Receptor Knockout Mice
Autor: Susanne Syberg, Solveig Petersen, Jens-Erik Beck Jensen, Alison Gartland, Jenni Teilmann, Iain Chessell, Thomas H. Steinberg, Peter Schwarz, Niklas Rye Jørgensen
Publikováno v: Journal of Osteoporosis, Vol 2012 (2012)
The purinergic P2X7 receptor is expressed by bone cells and has been shown to be important in both bone formation and bone resorption. In this study we investigated the importance of the genetic background of the mouse strains on which the P2X7 knock
Externí odkaz: https://doaj.org/article/8ff3cad7aa064479925ea51e018b83f2
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2
Akademický článek
Association between P2X7 Receptor Polymorphisms and Bone Status in Mice
Autor: Susanne Syberg, Peter Schwarz, Solveig Petersen, Thomas H. Steinberg, Jens-Erik Beck Jensen, Jenni Teilmann, Niklas Rye Jørgensen
Publikováno v: Journal of Osteoporosis, Vol 2012 (2012)
Macrophages from mouse strains with the naturally occurring mutation P451L in the purinergic receptor P2X7 have impaired responses to agonists (1). Because P2X7 receptors are expressed in bone cells and are implicated in bone physiology, we asked whe
Externí odkaz: https://doaj.org/article/ecf330bba2b646d69b8eb3f79dfc512f
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7
Hypophosphatemic Hypovitaminosis D Induces Osteomalacia in the Adult Female Rat
Autor: Niklas Rye Jørgensen, Klas S P Abelson, Jens Lykkesfeldt, Solveig Petersen, Darshana Durup, Erik Frandsen, Lars Thorbjørn Jensen, Anne-Marie Heegaard, Marta Diaz-delCastillo, Ming Ding, Lars Pedersen, Susanne Syberg, Jesper Morgenlykke
Publikováno v: Durup, D, Diaz-delCastillo, M, Morgenlykke, J, Jensen, LT, Frandsen, E, Abelson, KSP, Pedersen, L, Lykkesfeldt, J, Ding, M, Jørgensen, N R, Syberg, S, Petersen, S & Heegaard, AM 2020, ' Hypophosphatemic Hypovitaminosis D Induces Osteomalacia in the Adult Female Rat ', Endocrinology, vol. 161, no. 8 . https://doi.org/10.1210/endocr/bqaa100
Osteomalacia is a bone-demineralizing disease of adulthood, often caused by hypovitaminosis D. Current animal models of the disease mimic osteomalacia as a consequence of gastric bypass or toxic exposure to metals, but a relevant model of diet-induce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32bdc6590a1423fef18f9d751c623f7f
https://portal.findresearcher.sdu.dk/da/publications/90673c3c-d109-4ea0-b30f-1f5da7e11852
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8
The role of the P2X7 receptor on bone loss in a mouse model of inflammation-mediated osteoporosis
Autor: Solveig Petersen, Susanne Syberg, Niklas Rye Jørgensen, Ming Ding, T. M. Kvist, Peter Schwarz
Publikováno v: Bone Reports, Vol 7, Iss C, Pp 145-151 (2017)
Kvist, T M, Syberg, S, Petersen, S, Ding, M, Jørgensen, N R & Schwarz, P 2017, ' The role of the P2X7 receptor on bone loss in a mouse model of inflammation-mediated osteoporosis ', Bone Reports, vol. 7, pp. 145-151 . https://doi.org/10.1016/j.bonr.2015.09.003
Bone Reports
Kvist, T M, Syberg, S, Petersen, S, Ding, M, Rye Jørgensen, N & Schwarz, P 2017, ' The role of the P2X7 receptor on bone loss in a mouse model of inflammation-mediated osteoporosis ', Bone Reports, vol. 7, pp. 145-151 . https://doi.org/10.1016/j.bonr.2015.09.003
In inflammatory autoimmune diseases, bone loss is frequent. In most cases, secondary osteoporosis is caused by treatment with systemic glucocorticoid. However, the pathogenesis behind the bone loss is presumed multifactorial. We aimed to elucidate th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f434a29cfa5cf47e5d44d1c345c642fc
https://doi.org/10.1016/j.bonr.2015.09.003
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9
Fine-tuned ATP signals are acute mediators in osteocyte mechanotransduction
Autor: Ole Vang, Peter Schwarz, Susanne Syberg, Niklas Rye Jørgensen, Christina K.B. Andersen, Derya Aslan, Tina M. Kringelbach, Maria Ellegaard, Ivana Novak, Kim A. Kristiansen
Publikováno v: Cellular Signalling. 27:2401-2409
Osteocytes are considered the primary mechanosensors of bone, but the signaling pathways they apply in mechanotransduction are still incompletely investigated and characterized. A growing body of data strongly indicates that P2 receptor signaling amo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145e4a0474ce99ad4e89dda970599836
https://doi.org/10.1016/j.cellsig.2015.08.016
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10
Adipose derived mesenchymal stem cells – Their osteogenicity and osteoblast in vitro mineralization on titanium granule carriers
Autor: Niklas Rye Jørgensen, Morten Dahl, Else Marie Pinholt, Susanne Syberg
Publikováno v: Journal of Cranio-Maxillofacial Surgery. 41:e213-e220
Purpose Adipose derived mesenchymal stem cells (ADMSCs) may be osteogenic, may generate neoangiogenisis and may be progenitors for differentiated osteoblast mineralization. Titanium granules may be suitable as carriers for these cells. The aim was to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06942432dc890220a2523479b09e7ec4
https://doi.org/10.1016/j.jcms.2013.01.021
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