Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Susanne Sprung"'
Autor:
Maria do Carmo Greier, Annette Runge, Jozsef Dudas, Roland Hartl, Matthias Santer, Daniel Dejaco, Teresa Bernadette Steinbichler, Julia Federspiel, Christof Seifarth, Marko Konschake, Susanne Sprung, Sieghart Sopper, Avneet Randhawa, Melissa Mayr, Benedikt Gabriel Hofauer, Herbert Riechelmann
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundHead and neck squamous cell carcinomas (HNSCC) are highly heterogeneous tumors. In the harsh tumor microenvironment (TME), metabolic reprogramming and mitochondrial dysfunction may lead to immunosuppressive phenotypes. Aerobic glycolysis is
Externí odkaz:
https://doaj.org/article/7e69a60e5eab45c68f556a77a7892fb6
Autor:
Stefan Koeck, Arno Amann, Johan Kern, Marit Zwierzina, Edith Lorenz, Sieghart Sopper, Heinz Zwierzina, Finn Mildner, Martina Sykora, Susanne Sprung, Hubert Hackl, Florian Augustin, Hubert T. Maier, Andreas Pircher, Georg Pall, Dominik Wolf, Gabriele Gamerith
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTCancer associated fibroblasts (CAF) are known to orchestrate multiple components of the tumor microenvironment, whereas the influence of the whole stromal-fibroblast compartment is less understood. Here, an extended stromal fibroblast signatu
Externí odkaz:
https://doaj.org/article/b8859450d2444344a0b717d8fca9bf03
Autor:
Ankur Chakravarthy, Ian Reddin, Stephen Henderson, Cindy Dong, Nerissa Kirkwood, Maxmilan Jeyakumar, Daniela Rothschild Rodriguez, Natalia Gonzalez Martinez, Jacqueline McDermott, Xiaoping Su, Nagayasau Egawa, Christina S. Fjeldbo, Vilde Eide Skingen, Heidi Lyng, Mari Kyllesø Halle, Camilla Krakstad, Afschin Soleiman, Susanne Sprung, Matt Lechner, Peter J. I. Ellis, Mark Wass, Martin Michaelis, Heidi Fiegl, Helga Salvesen, Gareth J. Thomas, John Doorbar, Kerry Chester, Andrew Feber, Tim R. Fenton
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Human papillomavirus (HPV) is a known cause of cervical cancer. Here, the authors perform a multi-omic analysis using published cervical squamous cell carcinoma cohorts from the USA, Europe, and SubSaharan Africa and identify two cervical squamous ce
Externí odkaz:
https://doaj.org/article/9a5c4607e718467ca9be497358a18ce0
Patient-derived head and neck tumor slice cultures: a versatile tool to study oncolytic virus action
Autor:
Annette Runge, Melissa Mayr, Theresa Schwaiger, Susanne Sprung, Paolo Chetta, Timo Gottfried, Jozsef Dudas, Maria C. Greier, Marlies C. Glatz, Johannes Haybaeck, Knut Elbers, Herbert Riechelmann, Patrik Erlmann, Monika Petersson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Head and neck cancer etiology and architecture is quite diverse and complex, impeding the prediction whether a patient could respond to a particular cancer immunotherapy or combination treatment. A concomitantly arising caveat is obviously t
Externí odkaz:
https://doaj.org/article/9be346a1f80d49898d19c4d438e8b102
Autor:
Aparna Gunda, Chetana Basavaraj, Chandra Prakash Serkad V, Manjula Adinarayan, Ramu Kolli, Mallikarjuna Siraganahalli Eshwaraiah, Cristina Saura, Fiorella Ruiz, Patricia Gomez, Vicente Peg, Jose Jimenez, Susanne Sprung, Heidi Fiegl, Christine Brunner, Daniel Egle, GS Bhattacharyya, Manjiri M Bakre
Publikováno v:
Breast, Vol 63, Iss , Pp 1-8 (2022)
CanAssist Breast (CAB), a prognostic test uses immunohistochemistry (IHC) approach coupled with artificial intelligence-based machine learning algorithm for prognosis of early-stage hormone-receptor positive, HER2/neu negative breast cancer patients.
Externí odkaz:
https://doaj.org/article/bf93f3ec223f418db3bb9ab9cf75700c
The impact of G protein-coupled oestrogen receptor 1 on male breast cancer: a retrospective analysis
Autor:
Jan-Hendrik Maiwald, Susanne Sprung, Piotr Czapiewski, Wiebke Lessel, Anna Scherping, Dirk Schomburg, Markus Plaumann, Bartłomiej Tomasik, Gerhard Behre, Johannes Haybaeck, Atanas Ignatov, Holm Eggemann, Norbert Nass
Publikováno v:
Contemporary Oncology, Vol 25, Iss 3, Pp 204-212 (2021)
Externí odkaz:
https://doaj.org/article/179317c9bb75411180c0f5c3fddb17c1
Autor:
Konstantin R. Brawanski, Susanne Sprung, Christian F. Freyschlag, Romana Hoeftberger, Thomas Ströbel, Johannes Haybaeck, Claudius Thomé, Claudia Manzl, Anna M. Birkl-Toeglhofer
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6184 (2023)
Glioblastoma is the most common malignant brain tumor in adults. Standard treatment includes tumor resection, radio-chemotherapy and adjuvant chemotherapy with temozolomide (TMZ). TMZ methylates DNA, whereas O6-methylguanine DNA methyltransferase (MG
Externí odkaz:
https://doaj.org/article/5c3d9fd290e141dd8176f3b85a727e33
Autor:
Matt Lechner, Volker H. Schartinger, Christopher D. Steele, Wen Long Nei, Marc Lucas Ooft, Liesa-Marie Schreiber, Christodoulos P. Pipinikas, Grace Tin-Yun Chung, Yuk Yu Chan, Feng Wu, Ka-Fai To, Chi Man Tsang, Wayne Pearce, Daniele Morelli, Martin Philpott, Liam Masterson, Reshma Nibhani, Graham Wells, Christopher G. Bell, Julia Koller, Susanne Delecluse, Yim Ling Yip, Jacklyn Liu, Cillian T. Forde, Martin D. Forster, Amrita Jay, József Dudás, Annika Krapp, Simon Wan, Christian Uprimny, Susanne Sprung, Johannes Haybaeck, Tim R. Fenton, Kerry Chester, Christina Thirlwell, Gary Royle, Teresa Marafioti, Rajeev Gupta, Sagung Rai Indrasari, Camelia Herdini, Mohd Afiq Mohd Slim, I. Indrawati, Liam Sutton, Renske Fles, Bing Tan, Joe Yeong, Amit Jain, Shuting Han, Haitao Wang, Kelvin S. H. Loke, Wan He, Ruilian Xu, Hongtao Jin, Zhiqiang Cheng, David Howard, Peter H. Hwang, Quynh-Thu Le, Joshua K. Tay, Robert B. West, Sai Wah Tsao, Tim Meyer, Herbert Riechelmann, Udo Oppermann, Henri-Jacques Delecluse, Stefan M. Willems, Melvin L. K. Chua, Pierre Busson, Kwok Wai Lo, Guido Wollmann, Nischalan Pillay, Bart Vanhaesebroeck, Valerie J. Lund
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nasopharyngeal carcinoma (NPC) lacks effective diagnostic and therapeutic strategies, in particular at advanced stages. Here, the authors show that expression of the somatostatin receptor 2 is induced by Epstein-Barr virus in NPC and has a key role i
Externí odkaz:
https://doaj.org/article/ff5d4bfec0f74e349a04c2a36d9baae8
Autor:
Lisa Mayr, Felix Grabherr, Julian Schwärzler, Isabelle Reitmeier, Felix Sommer, Thomas Gehmacher, Lukas Niederreiter, Gui-Wei He, Barbara Ruder, Kai T. R. Kunz, Piotr Tymoszuk, Richard Hilbe, David Haschka, Clemens Feistritzer, Romana R. Gerner, Barbara Enrich, Nicole Przysiecki, Markus Seifert, Markus A. Keller, Georg Oberhuber, Susanne Sprung, Qitao Ran, Robert Koch, Maria Effenberger, Ivan Tancevski, Heinz Zoller, Alexander R. Moschen, Günter Weiss, Christoph Becker, Philip Rosenstiel, Arthur Kaser, Herbert Tilg, Timon E. Adolph
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Dietary lipids are linked to the development of inflammatory bowel diseases through unclear mechanisms. Here, the authors report that dietary polyunsaturated fatty acids trigger intestinal inflammation resembling aspects of Crohn’s disease, which i
Externí odkaz:
https://doaj.org/article/fc87842ee61c451c8bde60fdd9105dee
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2482 (2022)
This study aims to investigate the role of partial epithelial to mesenchymal transition (pEMT)-related proteins in modulating Cisplatin resistance in head and neck squamous cell carcinoma (HNSCC). SCC-25 cells were pre-treated with TGF-beta1 followed
Externí odkaz:
https://doaj.org/article/f71f328c5ae64684b0c1667f07a05df7